Condition

Old Age clinical trials and research

• 16Clinical trials
• 13NIH research projects
• 9Countries

Newest Old Age clinical trials

All recruiting trials (16)

• Fall Prevention Pathways: A digital program to help older adults reduce fall risk

  A digital, remotely monitored 8-week program is being tested to see if it can reduce fall risk in community-dwelling adults aged 65–85 who are at low to moderate risk.

  Recruiting Emory University · Atlanta, Georgia · NCT07824141

• Mental effort with light resistance training for older adults

  This study tests whether adding a mental effort cue to light resistance training helps older adults build more strength and improve neuromuscular function than light training alone.

  Recruiting Kennesaw State University · Kennesaw, Georgia · NCT07687316

• Combined NMES and Low-Intensity Resistance Training in Older Adults

  This study tests whether pairing electrical stimulation with light resistance training helps older adults gain muscle strength and endurance.

  Recruiting Riphah International University · Lahore, Punjab Province · NCT07646405

• Inspiring Seniors to Exercise More with Personalized Music

  This study tests whether personalized tempo-matched music playlists help sedentary adults age 65 and older exercise more and feel better about physical activity.

  Recruiting Emory University · Atlanta, Georgia · NCT07629739

• Home safety modifications to prevent falls in older adults in Guangzhou

  This project will try simple home changes like anti-slip mats, better lighting, and minor hazard fixes to see if they reduce falls among community-dwelling people aged 60–80 in Guangzhou over 12 months.

  Recruiting Guangzhou Center for Disease Control and Prevention · Guangzhou, Guangdong · NCT07458958

• Blood biomarkers to predict cognitive/functional decline and mortality in hospitalized older adults

  This project will test whether specific blood biomarkers can help predict dementia-related decline, rehospitalization, and one-year mortality in older adults hospitalized with neurological or other medical problems.

  Recruiting at 3 sites Istituto Nazionale di Ricovero e Cura per Anziani · Ancona and 2 other locations · NCT07435467

• CDK4/6 drugs for older women with breast cancer

  This project will test whether CDK4/6 drugs work as well and are as safe in women aged 70 and older with breast cancer as they are in younger women, using real-world medical records and follow-up.

  Recruiting Fondazione IRCCS Policlinico San Matteo di Pavia · Pavia, Pavia · NCT07399808

• Sexuality and mental health in people aged 60 and over

  This project will see if aspects of sexuality are linked with mental health in people aged 60 and over who live in the community.

  Recruiting University Hospital, Clermont-Ferrand · Clermont-Ferrand · NCT07252583

• Examining blood pressure variability and frailty in older adults

  This study is trying to see how changes in blood pressure affect frailty in older adults with high blood pressure who are 75 and older.

  Recruiting Istituto Auxologico Italiano · Milan · NCT06868069

• Physical exercise program for older adults in a rural area

  This project tests whether a community exercise program increases weekly moderate-to-vigorous physical activity measured by an accelerometer in adults over 59 compared with new participants and active controls.

  Recruiting University of Valencia · Valencia · NCT06842849

• Extended-release tacrolimus to improve thinking and memory in older kidney transplant recipients

  This will try switching older kidney transplant recipients from immediate-release tacrolimus to an extended-release formulation to see if it improves thinking, memory, or other cognitive symptoms.

  Recruiting Phase 4 Massachusetts General Hospital · Boston, Massachusetts · NCT06751992

• Impact of Adult Day Programs on Dementia Patients and Their Caregivers

  This study is trying to see how attending adult day programs affects the well-being of people with dementia and their family caregivers compared to those who don’t attend these programs.

  Recruiting York University · Edmonton & Calgary, Alberta and 3 other locations · NCT06496945

• Improving physical performance in older hospitalized patients through personalized nutrition and exercise

  This study is testing if personalized nutrition and exercise can help older patients in the hospital improve their physical performance and stay active after they go home.

  Recruiting Radboud University Medical Center · Nijmegen, Gelderland · NCT05413616

• Training to improve balance and cognitive function in older adults with mild cognitive impairment

  This study is testing a new training program that helps older adults with mild cognitive impairment improve their balance and thinking skills to reduce their risk of falling.

  Recruiting University of Illinois Chicago · Chicago, Illinois · NCT04938349

• Improving recovery in elderly patients with frailty undergoing surgery for digestive cancer

  This study tests whether a special program that includes nutrition and exercise can help older patients with frailty recover better after surgery for digestive cancer.

  Recruiting Peking University First Hospital · Beijing, Beijing Municipality · NCT04715581

• Health promotion for frail older people using eHealth

  This study is testing a new digital support program to help frail older adults manage their health better with the help of healthcare providers and personalized resources.

  Recruiting Göteborg University · Gothenburg, Gothenburg · NCT04416815

NIH-funded research (13)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Neural factors behind age-related breathing problems

  This grant studies why breathing control gets weaker with age and how nerve cells that control strong breaths deteriorate, aiming to improve airway clearance and reduce pneumonia risk in older adults.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11425689

• Menopause, aging, and everyday functioning in women

  A long-term study following 3,302 diverse women to understand how the menopause transition affects health and daily functioning as they age.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11421739

• A druggable mito-nuclear feedback mechanism that preserves mitochondrial and synaptic function in old age

  A new NIH-funded program aims to understand a brain mechanism that links mitochondria to gene control, with the goal of keeping brain cells happy in aging and Alzheimer's-related dementias.

  NIH research Scripps Research Institute, the · La Jolla, United States · NIH-11411346

• Respiratory control in aging: keeping breathing muscles healthy

  A Mayo Clinic team is testing ways to protect the breathing muscles in people as they age, aiming to keep seniors breathing well longer.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11384755

• How aging affects natural antibodies from a special B cell type and why it matters for older adults

  This NIH grant explores how aging changes a specific B cell type that makes natural antibodies, which could influence how well older people are protected from infections.

  NIH research Western Michigan Univ School of Medicine · Kalamazoo, United States · NIH-11361634

• Understanding how natural immunity changes with age in men and women

  This project looks at how our natural defenses, called B1 cells, stay strong or weaken as we get older, especially noticing differences between men and women.

  NIH research Western Michigan Univ School of Medicine · Kalamazoo, United States · NIH-11192909

• How aging affects breathing control

  Testing treatments that protect the nerve cells that control breathing in older adults to reduce age-related respiratory weakness.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11135475

• How Goals Help Older Adults Remember Important Things

  This project looks at how setting goals can help older adults remember important information, especially when they feel rushed or stressed.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11109712

• Understanding Eye Repair in Older Age

  This work explores how eye cells repair themselves in older age, hoping to find ways to boost natural healing.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11097273

• Removing p21-high aging cells to improve healthy lifespan

  This project sees whether removing a specific type of aging cell called 'p21-high' can help older adults stay healthier and live longer.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11039923

• Understanding how aging affects movement in the spinal cord

  This study is looking at how aging affects the nerve cells in the spinal cord that control movement in people over 65, with the hope of finding ways to help older adults keep or regain their ability to move easily.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11007164

• Understanding how long-term cannabis use affects aging in older adults

  This study is looking at how long-term cannabis use affects the health and memory of older adults who have used it regularly for many years, especially as they get older and face risks like Alzheimer's disease.

  NIH research Duke University · Durham, United States · NIH-10764226

• How midlife health and menopause affect aging in women

  This study looks at how women's health during midlife, especially around menopause, affects how well they age later in life, and it's for women who want to understand the connection between their health now and their future well-being.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-10698181

Related topics

Quick answers

How many Old Age clinical trials are recruiting right now?

16, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (5 trials), Italy (3 trials), China (2 trials), France (1 trial), Netherlands (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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