Clinical trial Recruiting at 1 site Interventional Ages 65 to 85

Mental effort with light resistance training for older adults

Official title: The Effect of Maximal Mental Effort During Resistance Training on Physical Function and Motor Unit Behavior in Older Adults

Run by Kennesaw State University · NCT07687316 · Data updated 2026-11-12

This study tests whether adding a mental effort cue to light resistance training helps older adults build more strength and improve neuromuscular function than light training alone.

Quick facts

Study typeInterventional
Ages65 Years to 85 Years
SexAll
Enrollment75 (estimated)
SponsorKennesaw State University
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Kennesaw, Georgia)
StatusRecruiting
StartedJune 6, 2026
Main results expectedDecember 2027
Study endsDecember 2027
Registry record updatedJuly 8, 2026
Trial IDNCT07687316 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged in the senior range who are otherwise ambulatory and not engaging in regular structured exercise in the past 2 years.

Probably not a fit

Individuals with high risk cardiovascular or other disqualifying conditions or those unable to participate in even light resistance training may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Older adults will be randomized to one of three groups: light-intensity resistance training, light-intensity resistance training with maximal mental effort, or a non-training control. The 8-week program includes supervised, whole-body exercises twice weekly, with progressive sets and rest periods. The primary focus is on changes in strength, neuromuscular function, physical function, and body composition. Outcomes are measured before and after the program to compare the training groups against the control.

Why it matters

Potential benefit: If successful, this approach could enhance strength and neuromuscular adaptations with low physical demand for older adults.

How similar studies have gone: Prior research supports using targeted mental strategies to augment training adaptations, with mixed but promising results for neuromuscular gains.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Body mass index between 18.5 - 33 kg·m2
* No structured physical activity in past 2 years
* Any unstable condition contradicting exercise
* Independently walk with or without assistive device
* No significant cognitive impairment

Exclusion Criteria:

* Score of 22 or lower on Montreal Cognitive Assessment
* Missing more than 3 training sessions (training groups only)
* Pacemaker
* Unstable angina
* Symptomatic heart failure
* Uncontrolled arrythmias
* Uncontrolled hypertension (greater or equal to 160/90)
* Myocardial infarction in the past 6 months
* Uncontrolled type 2 diabetes
* Type 1 diabetes
* Severe or unstable pulmonary conditions,
* Currently on supplemental oxygen therapy
* Severe hearing loss or visual impairment
* Alzheimer's Disease or significant cognitive impairment
* Stroke in the past 6 months or ongoing stroke-induced motor impairment
* Any neurological (e.g., Parkinson's) condition affecting motor control
* Undergoing chemotherapy
* Surgery in past 6 months
* Musculoskeletal injury in the past 6 months
* Terminal illness
* Stage 3 or greater chronic kidney disease

Where it's running

  • Kennesaw State University
    Kennesaw, Georgia, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.