Clinical trial Recruiting at 1 site Observational Ages 1 Year to 25

Examining the NUDT15 gene's role in inflammatory bowel disease in Taiwan

Official title: The Prevalence and Impacts of Nudix Hydrolase 15 (NUDT15) Gene Variants in Taiwanese Inflammatory Bowel Disease

Run by National Taiwan University Hospital · NCT06913998 · Data updated 2026-11-12

This study looks at how the NUDT15 gene affects children with inflammatory bowel disease in Taiwan to see if it can help improve their treatment.

More Inflammatory Bowel Diseases trials

Quick facts

Study typeObservational
Ages1 Year to 25 Years
SexAll
Enrollment65 (estimated)
SponsorNational Taiwan University Hospital
Academic / other
Locations1 site (Taipei)
StatusRecruiting
StartedDecember 27, 2023
Main results expectedJanuary 2026
Study endsNovember 2026
Registry record updatedApril 8, 2025
Trial IDNCT06913998 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals diagnosed with inflammatory bowel disease who are willing to undergo a blood test for genetic evaluation.

Probably not a fit

Patients who refuse to participate in the blood test for NUDT15 gene evaluation will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients diagnosed with inflammatory bowel disease (IBD) at National Taiwan University Children's Hospital. Participants will undergo a blood test to evaluate the NUDT15 gene, which is known to influence the risk of neutropenia when using thiopurines for treatment. The study aims to summarize the prevalence and impacts of NUDT15 gene variants in the context of IBD in Taiwan, analyzing the gene test results alongside other clinical data to improve treatment strategies.

Why it matters

Potential benefit: If successful, this study could lead to more personalized and safer treatment options for patients with inflammatory bowel disease.

How similar studies have gone: Previous studies have indicated the significance of NUDT15 gene variants in Asian populations, suggesting that this approach is both relevant and potentially impactful.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participants who are diagnosed with inflammatory bowel disease.

Exclusion Criteria:

* Participants who refused to have blood test for NUDT15 gene evaluation.

Where it's running

  • National Taiwan University Hospital
    Taipei, Taiwan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.