Condition
Nasopharyngeal Carcinoma clinical trials and research
As of November 12, 2026, Find a Trial lists 74 Nasopharyngeal Carcinoma clinical trials that are recruiting, at sites in 4 countries (most in China (65), Singapore (5), United States (4)). By phase: Phase 3 (28), Phase 2 (19), Phase 1 (2), Phase 1/2 (1). The most active sponsors are Sun Yat-sen University (36), Fudan University (4), Jiangxi Provincial Cancer Hospital (3). There are also 3 NIH-funded research projects on Nasopharyngeal Carcinoma, with $1.1 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 74Clinical trials
- 3NIH research projects
- 4Countries
Newest Nasopharyngeal Carcinoma clinical trials
All recruiting trials (74)
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Docetaxel and SX-682 in head and neck cancers and prostate cancer
This trial tests a new drug SX-682 together with docetaxel in adults whose head and neck cancers or prostate cancer have returned or spread.
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Becotatug Vedotin for EGFR-positive relapsed, refractory, or metastatic pediatric solid tumors
This trial will test Becotatug Vedotin, an EGFR-targeted antibody-drug conjugate, to see if it is safe and helps children aged 2–18 with EGFR-positive relapsed, refractory, or metastatic solid tumors.
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Induction and maintenance with MRG003, Tislelizumab, and Capecitabine for locally recurrent nasopharyngeal cancer
This study tests a treatment combo of MRG003 and a PD-1 blocker first, then continues with Capecitabine plus the PD-1 blocker to see if it helps patients with locally recurrent NPC.
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Lower-dose (40.2 Gy) versus standard-dose (49.2 Gy) radiotherapy to low‑risk areas for chemosensitive Stage II nasopharyngeal cancer
This trial will try a lower radiotherapy dose (40.2 Gy) instead of the standard 49.2 Gy for people with stage II nasopharyngeal cancer who had a strong response to induction chemo and have undetectable EBV DNA.
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Screening for early nasopharyngeal (nose) cancer
This project tests whether blood and saliva markers can find nasopharyngeal cancer early in adults aged 35 to 60 who are at higher risk because of ethnicity or family history.
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Proton versus photon radiation for nasopharyngeal cancer
This trial will test whether proton radiation works at least as well as standard photon radiation for adults newly diagnosed with nasopharyngeal cancer that has not spread.
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Treatment for operable recurrent nasopharyngeal carcinoma
This study is testing a new combination of medications for patients with operable recurrent nasopharyngeal cancer to see if it helps them live longer without the cancer coming back.
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ImmunoPET imaging for detecting malignant cancers
This study is testing a new imaging method to see if it can better detect certain types of cancer in patients who have or might have these diseases.
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Treatment for advanced nasopharyngeal carcinoma using targeted therapy and immunotherapy.
This study is testing a new combination of targeted therapy and immunotherapy with chemotherapy to see if it helps people with advanced nasopharyngeal cancer live longer without their disease getting worse.
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Optimizing radiotherapy to protect thyroid function in nasopharyngeal carcinoma patients
This study is testing whether a new way of giving radiotherapy can better protect the thyroid gland in patients with nasopharyngeal cancer compared to the standard treatment.
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Using a dental stent to protect taste in nasopharyngeal cancer patients during treatment
This study is testing if a special dental stent can help people with nasopharyngeal cancer keep their sense of taste while they undergo chemotherapy and radiation treatment.
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Comparing surgery alone to surgery with low-dose radiotherapy for early-stage nasopharyngeal cancer
This study is testing whether adding low-dose radiotherapy to surgery can help people with early-stage nasopharyngeal cancer live longer and have fewer side effects compared to surgery alone.
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Induction chemotherapy followed by guided radiation for EBV-related nasopharyngeal cancer
This study is testing a new way to treat EBV-related nasopharyngeal cancer by using a special type of chemotherapy followed by targeted radiation to see if it can reduce side effects while still being effective.
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Comparing two types of radiotherapy for advanced nasopharyngeal carcinoma after chemotherapy
This study is testing whether a new type of radiotherapy that lowers the dose in certain areas can help people with advanced nasopharyngeal cancer who have responded to chemotherapy feel better compared to standard treatment.
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Combination treatment for advanced Epstein-Barr Virus associated nasopharyngeal carcinoma
This study is testing a new combination of treatments for people with advanced Epstein-Barr Virus related nasopharyngeal cancer to see if it works better than the usual options.
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Comparing endoscopic surgery and radiotherapy for early-stage nasopharyngeal cancer
This study is testing whether endoscopic surgery or radiotherapy works better for people with early-stage nasopharyngeal cancer and how each treatment affects their recovery.
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Comparing two treatment methods for operable nasopharyngeal carcinoma
This study is testing which treatment method works better for people with operable nasopharyngeal carcinoma: surgery with a specific type of chemoradiotherapy or surgery with a different dose of chemoradiotherapy.
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Online adaptive radiotherapy for nasopharyngeal carcinoma
This study is testing if a new type of online adaptive radiotherapy can help people with nasopharyngeal carcinoma live longer and feel better compared to traditional radiotherapy.
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Targeted alpha therapy [212Pb]VMT-Alpha-NET for SSTR-positive metastatic or inoperable GI neuroendocrine, pheochromocytoma/paraganglioma, small cell lung, kidney, and head & neck cancers
This trial will try an experimental targeted alpha-particle drug called [212Pb]VMT-Alpha-NET in adults whose metastatic or inoperable tumors show somatostatin receptor (SSTR) expression.
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Combining BL-B01D1 and PD-1 Antibody for Advanced Lung and Nasopharyngeal Cancers
This study is testing a new combination of two cancer treatments to see if it can help people with advanced lung and nasopharyngeal cancers feel better and live longer.
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Deep learning model for diagnosing skull-base osteonecrosis in nasopharyngeal carcinoma patients
This study is testing a new computer program to see if it can better diagnose a serious condition called skull-base osteonecrosis in people who have had treatment for nasopharyngeal cancer.
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Comparing GP chemotherapy with and without adebrelimab for nasopharyngeal carcinoma
This study is testing if adding a new immune treatment called adebrelimab to standard chemotherapy can help people with advanced nasopharyngeal cancer respond better to treatment and live longer.
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Evaluating a new test for diagnosing nasopharyngeal carcinoma
This study is testing a new kit that checks for a specific virus in patients to see if it can help doctors better diagnose nasopharyngeal carcinoma.
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Comparing two treatment regimens for high-risk nasopharyngeal carcinoma
This study is testing a new combination of treatments for patients with high-risk nasopharyngeal cancer to see if it works better than the standard treatment.
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Using HCQ before treatment for advanced nasopharyngeal carcinoma
This study is testing if giving hydroxychloroquine to patients with advanced nasopharyngeal cancer before their treatment can help prevent cancer from coming back.
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Combining Tislelizumab with chemotherapy for treating advanced nasopharyngeal cancer with bone metastasis
This study is testing two different treatment combinations for people with advanced nasopharyngeal cancer that has spread to the bones to see which one works better and is safer.
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Combining Adebrelimab with Chemotherapy and Radiation for Advanced Nasopharyngeal Cancer
This study is testing if adding a new drug called Adebrelimab to standard chemotherapy and radiation can help people with advanced nasopharyngeal cancer feel better and improve their chances of recovery.
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Combining targeted therapies and chemotherapy for advanced nasopharyngeal carcinoma
This study is testing a new treatment that combines targeted therapies and chemotherapy to see if it helps people with advanced nasopharyngeal carcinoma feel better and live longer.
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Counting Epstein-Barr Virus DNA in Blood for Nasopharyngeal Carcinoma Patients
This study is testing a new blood test to see if counting Epstein-Barr Virus DNA can help doctors better monitor treatment responses in patients with nasopharyngeal carcinoma.
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Reducing radiation for nasopharyngeal cancer after immunotherapy and chemotherapy
This study is testing if giving less radiation to patients with nasopharyngeal cancer who have responded well to immunotherapy and chemotherapy can help them feel better while reducing side effects.
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Assessing SAA1 Levels to Predict Oral Mucositis from Radiotherapy
This study is testing if measuring a specific protein in the blood can help predict how severe mouth sores will be for patients with head and neck cancer who are getting radiation treatment.
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Comparing two chemotherapy regimens for nasopharyngeal carcinoma
This study is testing whether a new chemotherapy treatment for nasopharyngeal carcinoma can work better and cause fewer side effects than the standard treatment.
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Combining Toripalimab with Capecitabine for High-Risk Nasopharyngeal Carcinoma
This study is testing if combining toripalimab with capecitabine can help high-risk nasopharyngeal cancer patients avoid cancer coming back after their initial treatment.
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Personalized neck radiation for nasopharyngeal cancer patients
This study is testing if personalized neck radiation for nasopharyngeal cancer patients can reduce side effects and improve quality of life while still keeping survival rates high.
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Reduced-dose radiotherapy for stage III nasopharyngeal carcinoma
This study is testing whether a lower dose of radiation combined with chemotherapy and immunotherapy can help people with stage III nasopharyngeal carcinoma do just as well as those receiving the standard radiation dose.
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Using multi-omics to predict treatment outcomes for advanced nasopharyngeal cancer
This study is testing if new biological methods can help predict how well a combination of chemotherapy and immunotherapy will work for people with advanced nasopharyngeal cancer.
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Evaluating the impact of chemotherapy response in nasopharyngeal carcinoma
This study is trying to see if how well patients with advanced nasopharyngeal carcinoma respond to the first round of chemotherapy can give clues about their future health and immune system changes.
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Combining tislelizumab with different treatment regimens for nasopharyngeal carcinoma
This study is testing two different treatment combinations with tislelizumab to see which one works better for patients with recurrent or metastatic nasopharyngeal carcinoma.
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Using Tislelizumab and Metronomic Capecitabine for High-risk Nasopharyngeal Carcinoma
This study is testing if a combination of two treatments can help people with high-risk nasopharyngeal cancer who still have detectable Epstein-Barr virus after their initial chemotherapy stay cancer-free longer.
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Reduced-dose radiotherapy options for high-risk nasopharyngeal carcinoma patients
This study is testing if giving less radiation, with or without chemotherapy, can be just as effective for patients with high-risk nasopharyngeal cancer who have already responded well to initial treatment.
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Combining envafolimab with chemoradiotherapy for advanced nasopharyngeal carcinoma
This study is testing if adding a new drug called envafolimab to standard chemotherapy and radiation can help people with advanced nasopharyngeal cancer do better in their treatment.
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Comparing two treatments for advanced nasopharyngeal carcinoma
This study is testing a new combination treatment for advanced nasopharyngeal cancer to see if it works better than the standard treatment.
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Using Nivolumab with chemotherapy for nasopharyngeal carcinoma in children and adults
This study tests if adding the drug Nivolumab to regular chemotherapy can help children and adults with nasopharyngeal carcinoma respond better to treatment.
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Reducing radiation target volumes in nasopharyngeal carcinoma treatment
This study is testing if reducing the radiation area for patients with newly diagnosed nasopharyngeal cancer can improve their treatment outcomes and quality of life compared to the standard approach.
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Testing a new drug combination for advanced lung and nasopharyngeal cancers
This study is testing a new combination of drugs to see if it can help people with advanced lung cancer and nasopharyngeal cancer feel better and tolerate the treatment well.
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Induction chemotherapy with low-dose radiation and cadonilimab for locally advanced nasopharyngeal carcinoma
This study will try adding low-dose radiation and the immune drug cadonilimab to induction chemotherapy before standard concurrent chemoradiotherapy in adults with newly diagnosed locally advanced nasopharyngeal carcinoma.
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Dual-energy CT combined with nasopharyngeal endoscopy to detect nasopharyngeal carcinoma
This project will test whether doing dual-energy CT first and then nasopharyngeal endoscopy can better find nasopharyngeal carcinoma in adults who have high EBV-related blood markers.
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Comparing two surgical approaches for recurrent nasopharyngeal carcinoma after chemotherapy
This study is testing whether a less extensive surgery for recurrent nasopharyngeal cancer after chemotherapy can be just as effective as a more extensive surgery while reducing risks for patients.
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New treatment approach for advanced nasopharyngeal carcinoma
This study tests a new treatment combination for people with advanced nasopharyngeal cancer to see if it works better and is less harmful than the usual chemotherapy.
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New treatments for advanced nasopharyngeal cancer with detectable EBV DNA after chemotherapy
This study is testing if adding two new treatments, camrelizumab or nimotuzumab, to standard chemotherapy can help people with advanced nasopharyngeal cancer who still have detectable EBV DNA after their first round of treatment.
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Combining Sintilimab with Chemoradiotherapy for High-risk Nasopharyngeal Cancer
This study is testing a new treatment plan that combines a cancer drug called Sintilimab with chemotherapy and radiation to see if it helps people with high-risk nasopharyngeal cancer.
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Comparing radiotherapy alone to concurrent chemoradiotherapy for nasopharyngeal carcinoma patients with undetectable EBV DNA after chemotherapy
This study is testing if patients with nasopharyngeal cancer and undetectable EBV DNA after chemotherapy can safely receive just radiotherapy instead of the usual combination of chemotherapy and radiotherapy.
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Using EBV CAR-T and TCR-T cells to treat nasopharyngeal carcinoma
This study is testing two types of specially engineered immune cells to see if they can safely help people with nasopharyngeal carcinoma.
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Induction chemotherapy followed by radiation for advanced nasopharyngeal carcinoma
This study is testing if starting treatment with chemotherapy followed by radiation helps people with advanced nasopharyngeal cancer live longer and feel better compared to just radiation alone.
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Personalized treatment for nasopharyngeal carcinoma based on EBV DNA levels
This study is testing if tailoring chemotherapy for people with advanced nasopharyngeal carcinoma based on their EBV DNA levels can improve their chances of staying cancer-free.
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Combining radiotherapy with endostatin and capecitabine for nasopharyngeal carcinoma
This study is testing if combining radiotherapy with two medications, endostatin and capecitabine, can help people with nasopharyngeal cancer who didn't respond to initial chemotherapy.
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Treatment for locally advanced nasopharyngeal carcinoma using Nituzumab
This study is testing if adding a new drug called Nituzumab to standard chemotherapy can help people with locally advanced nasopharyngeal cancer live longer and have better treatment results.
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Screening for nasopharyngeal carcinoma using Epstein-Barr virus tests
This study is testing whether certain blood tests for the Epstein-Barr virus can help find nasopharyngeal cancer earlier in family members of patients who have it.
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Combining surgery with targeted chemoradiotherapy for nasopharyngeal cancer
This study is testing if combining surgery with a special type of chemotherapy and targeted radiation can help people with newly diagnosed nasopharyngeal cancer do better and have fewer side effects.
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Combining metronomic capecitabine with PD-1 antibody for high-risk nasopharyngeal carcinoma
This study is testing if adding a PD-1 antibody to a cancer drug called capecitabine can help people with high-risk nasopharyngeal carcinoma live longer after their initial treatment.
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Combining chemoradiotherapy with an anti-PD1 treatment for recurrent nasopharyngeal carcinoma
This study is testing if adding a new immune treatment to standard chemotherapy and radiation can help people with recurrent nasopharyngeal cancer feel better compared to just using chemotherapy and radiation alone.
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Combining toripalimab with radiotherapy for treating nasopharyngeal carcinoma
This study is testing if combining a new immunotherapy drug called toripalimab with radiotherapy can help people with nasopharyngeal cancer that has spread, and improve their chances of living longer and feeling better.
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Using immune scores and radiomics to improve staging in nasopharyngeal carcinoma
This study is testing a new way to stage nasopharyngeal cancer by combining immune system scores with imaging data to see if it can give a better understanding of patient outcomes and treatment options.
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Combining camrelizumab with targeted radiotherapy for advanced nasopharyngeal cancer
This study is testing if combining a new cancer drug with targeted radiation can help people with advanced nasopharyngeal cancer live longer and possibly be cured compared to just using the drug alone.
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Reduced-dose radiotherapy guided by PET/CT for nasopharyngeal cancer
This study is testing if giving a lower dose of radiation therapy, guided by special imaging, can still help people with nasopharyngeal cancer live longer while causing fewer side effects.
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Combining Toripalimab with Surgery for Recurrent Nasopharyngeal Carcinoma
This study is testing whether adding a new drug called Toripalimab to surgery can help people with recurrent nasopharyngeal cancer live longer and have better outcomes than surgery alone.
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Detecting how well chemotherapy works in patients with metastatic nasopharyngeal carcinoma using blood tests.
This study is testing if blood tests can help doctors see how well chemotherapy is working for people with metastatic nasopharyngeal carcinoma.
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Combining Toripalimab with Chemo-radiotherapy for Advanced Nasopharyngeal Cancer
This study is testing if adding a new drug called Toripalimab to standard chemo-radiotherapy can help people with advanced nasopharyngeal cancer live longer and feel better.
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Comparing reduced and conventional radiotherapy doses for nasopharyngeal carcinoma
This study is testing whether a lower dose of radiotherapy is just as effective and safe as the standard dose for patients with stage II-III nasopharyngeal cancer who have already received chemotherapy.
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Comparing nedaplatin and cisplatin for treating nasopharyngeal carcinoma
This study is testing whether a new chemotherapy drug called nedaplatin is as effective and safe as the standard drug cisplatin for treating advanced nasopharyngeal cancer.
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Standardized nutrition treatment to improve nutrition and outcomes in advanced nasopharyngeal cancer with malnutrition
This trial tests whether a standardized nutrition program during chemoradiation helps adults (18–65) with locally advanced nasopharyngeal cancer who have malnutrition.
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Concurrent chemotherapy with IMRT for recurrent nasopharyngeal carcinoma
This study is testing if adding chemotherapy with cisplatin to radiation therapy helps people with recurrent nasopharyngeal cancer do better and experience fewer side effects compared to just radiation alone.
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Screening for Nasopharyngeal Carcinoma Using EBV Biomarkers in Zhongshan City
This study is testing if certain blood tests for Epstein-Barr virus can help find nasopharyngeal cancer early in men and certain women living in Zhongshan and Wuzhou cities.
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Endoscopic surgery for early-stage nasopharyngeal cancer
This study tests if a new type of endoscopic surgery, combined with targeted radiation, can help people with early-stage nasopharyngeal cancer have better outcomes and fewer side effects than traditional surgery.
NIH-funded research (3)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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EBV-targeting immune T cells and checkpoint immunotherapy in nasopharyngeal cancer
This project looks at how EBV-specific T cells change during combination checkpoint immunotherapy and whether those changes relate to outcomes for people with EBV-driven nasopharyngeal cancer.
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Identifying a blood marker for nasopharyngeal cancer risk
This project looks for a specific antibody in blood that could tell us who might be at higher risk for developing nasopharyngeal cancer, especially in certain communities.
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Using a blood test to predict the risk of nasopharyngeal carcinoma linked to Epstein-Barr virus
This study is looking at a specific antibody in the blood that might help identify people at high risk for nasopharyngeal cancer, especially in Southeast Asians and immigrant Chinese communities, so we can catch the disease earlier and improve treatment outcomes.
Related topics
Quick answers
How many Nasopharyngeal Carcinoma clinical trials are recruiting right now?
74, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 4 countries. The most sites are in China (65 trials), Singapore (5 trials), United States (4 trials), Germany (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 28, Phase 2: 19, Phase 1: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.