Screening for nasopharyngeal carcinoma using Epstein-Barr virus tests

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of Epstein-Barr virus (EBV) antibody and DNA screening methods in first-degree relatives of patients with nasopharyngeal carcinoma. The investigators will conduct tests on various EBV antibodies and DNA using techniques such as ELISA and quantitative polymerase chain reaction. The goal is to identify the most effective screening method for detecting nasopharyngeal carcinoma in a high-risk population. Participants will be residents of Southern China who meet specific age and health criteria.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* residents in Southern China
* 30-62 years old
* male
* a first-degree relative of at least one nasopharyngeal carcinoma patient
* no medical record of nasopharyngeal carcinoma
* Eastern Cooperative Oncology Group score of 0-2
* be able to comprehend, sign, and date the written informed consent document to participate in the study

Exclusion Criteria:

* history of nasopharyngeal carcinoma
* heavy cardiovascular, liver or kidney disease
* on systemic steroid or immunosuppressant treatment or active autoimmune disease

Where it's running

• Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center
  Guangzhou, Guangdong, China Recruiting

Study contacts

• Study coordinator: Ming-Yuan Chen, MD, PhD
• Email: chmingy@mail.sysu.edu.cn
• Phone: 86-20-8734-3361

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.