Using multi-omics to predict treatment outcomes for advanced nasopharyngeal cancer
Official title: Investigation of Multi-omics Technique to Predict the Efficacy of Chemoradiotherapy Combined With Immunotherapy for Recurrent and/or Metastatic Nasopharyngeal Carcinoma
Run by Sun Yat-sen University · NCT06197776 · Data updated 2026-11-12
This study is testing if new biological methods can help predict how well a combination of chemotherapy and immunotherapy will work for people with advanced nasopharyngeal cancer.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Sun Yat-sen University Academic / other |
| Drugs / interventions | immunotherapy |
| Locations | 1 site (Guangzhou, Guangdong) |
| Status | Recruiting |
| Started | July 15, 2024 |
| Main results expected | December 2026 |
| Study ends | December 2028 |
| Registry record updated | May 11, 2026 |
| Trial ID | NCT06197776 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 to 70 with recurrent or metastatic nasopharyngeal carcinoma and an ECOG performance status of 0 to 1.
✕Probably not a fit
Patients with other malignant tumors, severe complications, or those who are pregnant or lactating may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to recruit 50 patients with recurrent or metastatic nasopharyngeal carcinoma to explore how multi-omics techniques can predict the effectiveness of a treatment regimen that combines chemoradiotherapy with immunotherapy. The study will analyze various biological data to identify potential biomarkers that correlate with treatment response. By understanding these predictive values, the research seeks to enhance personalized treatment strategies for patients suffering from this aggressive cancer.
Why it matters
Potential benefit: If successful, this study could lead to more effective and tailored treatment options for patients with recurrent and metastatic nasopharyngeal carcinoma.
How similar studies have gone: While the use of multi-omics in cancer treatment prediction is an emerging field, similar studies have shown promise in other cancer types, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Recurrent or metastatic nasopharyngeal carcinoma patients * All genders,range from 18~70 years old * ECOG score 0 \~ 1 * Inform consent form Exclusion Criteria: * Have or are suffering from other malignant tumors; * Participating in other clinical trials; * Drug or alcohol addition; * Do not have full capacity for civil acts; * Mental disorder; * Pregnancy or lactation; * Severe complication, eg, uncontrolled hypertension.
Where it's running
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Cancer Center, Sun Yat-sen University
Guangzhou, Guangdong, China Recruiting
Study contacts
- Principal investigator: Chong Zhao, M.D — Sun Yat-Sen University Cancer Center
- Study coordinator: Jingjing Miao, M.D
- Email: miaojingjing90@163.com
- Phone: 86-13631355201
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.