Condition

Mindfulness clinical trials and research

• 13Clinical trials
• 183NIH research projects
• 4Countries

Newest Mindfulness clinical trials

All recruiting trials (13)

• Brief audio-guided mindfulness for pain in orthopedic waiting rooms

  This trial tests whether listening to short mindfulness audio clips can help reduce pain for adults waiting for orthopedic care.

  Recruiting Florida State University · Tallahassee, Florida · NCT07562412

• Flexible online mindfulness program for pediatric residents

  This program will test whether letting pediatric residents choose a 3-, 5-, or 7-week online mindfulness course improves engagement, satisfaction, and completion compared with being assigned a length.

  Recruiting Northwestern University · Chicago, Illinois · NCT07542769

• Mindfulness training to reduce childbirth fear and strengthen bonding and breastfeeding in pregnant teens

  This program will try mindfulness-based stress reduction (MBSR) with pregnant teens and their partners to see if it lowers fear of childbirth, improves parent–infant bonding, and increases breastfeeding success.

  Recruiting Inonu University · Malatya, Malatya · NCT07540923

• Mindfulness and meditation lactation education for mothers of premature NICU infants

  This will test whether mindfulness and meditation training for mothers who are pumping for their premature NICU infants changes components of their breastmilk.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT07351799

• iWalk: an eight-week mindfulness walking program to build resilience

  This program tests whether an eight-week guided walking meditation can help adults with neurodegenerative conditions (like MS) improve resilience, mood, and self-regulation.

  Recruiting University of Illinois at Urbana-Champaign · Urbana, Illinois · NCT07285954

• Mindful-Breath program for people with COPD

  This program will test if a personalized Mindful-Breath telehealth and mindfulness approach helps adults aged 50–80 with COPD feel less stressed and become more active.

  Recruiting The University of Hong Kong · Hong Kong · NCT07195838

• Mindfulness and brain stimulation to improve thinking and mood in older adults in Taiwan

  This trial will test whether mindfulness programs or noninvasive brain stimulation can improve thinking skills and mood in older adults living in urban and rural Taiwan.

  Recruiting National Health Research Institutes, Taiwan · New Taipei City and 1 other locations · NCT07186023

• Recovering Together After Cardiac Arrest: a mind-body resilience program for survivors and caregivers.

  This project will try two brief mind-body programs to help cardiac arrest survivors and their caregivers reduce anxiety, depression, and emotional distress.

  Recruiting Icahn School of Medicine at Mount Sinai · Boston, Massachusetts and 1 other locations · NCT07143357

• Culturally adapted mindfulness to support thinking and memory in Latino older adults

  This study will test whether an 8-week culturally adapted mindfulness program can improve cognitive function, daily mindfulness, and brain/blood markers related to Alzheimer’s in Latino adults aged 65 and older.

  Recruiting Washington University School of Medicine · St Louis, Missouri · NCT07040904

• Bedtime mindfulness meditation for chronic trouble falling asleep

  This pilot will test whether a 4-week bedtime mindfulness app helps adults with chronic trouble falling asleep compared with an unguided meditation app or sleep hygiene education.

  Recruiting Phase 1/2 Brigham and Women's Hospital · Boston, Massachusetts · NCT06972303

• Mindfulness program for people with Parkinson's and their caregivers

  This study tests whether a mindfulness program can help people with Parkinson's and their caregivers feel better emotionally and improve their relationship.

  Recruiting The University of Hong Kong · Hong Kong · NCT06821230

• Eastern Principles Therapy for Injury Prevention in Nurses

  This study is testing if a new therapy based on Eastern mindfulness can help nurses and nursing aides in the U.S. and Thailand prevent work-related injuries and reduce stress better than traditional therapy or no treatment at all.

  Recruiting Bowling Green State University · Bowling Green, Ohio · NCT06813495

• Guanfacine plus mindfulness to support buprenorphine treatment for opioid use disorder.

  This trial will test whether adding the medication guanfacine and a mindfulness program to buprenorphine helps adults with opioid use disorder reduce cravings and stay in treatment.

  Recruiting Phase 1 Rutgers, The State University of New Jersey · Newark, New Jersey · NCT06642181

NIH-funded research (newest 40 of 183)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Mindfulness and Self-Hypnosis for Pain in Older Adults

  This grant tests non-drug ways like mindfulness and self-hypnosis to help people over 60 manage chronic pain.

  NIH research University of Washington · Seattle, United States · NIH-11599794

• Mindfulness-based Support for Pain and Sleep in Young People with Sickle Cell Disease

  A digital mindfulness program is being tailored for adolescents and young adults with sickle cell disease to help with pain and sleep and is being tested for practicality and early effectiveness.

  NIH research University of Illinois at Chicago · Chicago, UNITED STATES · NIH-11583056

• Mindfulness training to lower cardiovascular risk for moms and babies during pregnancy

  A mindfulness program is being tested during pregnancy to help prevent high blood pressure and heart problems for mothers and their babies.

  NIH research Rhode Island Hospital · Providence, United States · NIH-11582959

• Mindfulness-enhanced brain stimulation for depression

  This project tests whether combining a breath-focused attention training with targeted brain stimulation helps people with treatment-resistant depression think more clearly and feel better.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11516191

• Optimizing Opioid Tapering with Mindfulness for Chronic Pain

  A patient-friendly program tests a mindfulness-based approach to help adults with chronic pain reduce long-term opioid use safely.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11454728

• Prenatal mindfulness and inflammatory pathways to support mom and baby health

  A study from Oregon Health & Science University will explore how mindfulness during pregnancy might influence inflammatory signals and improve emotional well-being for mothers and healthy development for their children.

  NIH research Oregon Health & Science University · Portland, United States · NIH-11451269

• Mindfulness and psilocybin for chronic back pain

  A clinical study will explore how mindfulness training combined with a guided psilocybin experience may reduce pain for adults with chronic low back pain.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11449894

• Feasibility of a Mindfulness Program for Sheltered Homeless Youth

  A multi-site plan to test a trauma-informed mindfulness program for youth staying in shelters to help them stay calm, focused, and better able to handle stress.

  NIH research University of Texas Hlth Sci Ctr Houston · Houston, United States · NIH-11443738

• Mindfulness-based digital aftercare to support addiction recovery

  A digital mindfulness program delivered via a smartphone app to help adults stay sober after intensive addiction treatment.

  NIH research Yale University · New Haven, United States · NIH-11443402

• Remote mindfulness and coaching to boost activity after stroke

  A fully remote three-arm program tests whether adding mindful health coaching and gamified social support helps people stay active after stroke.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11440457

• Mobile mindfulness app to help spinal cord injury patients manage chronic pain

  A widely available mindfulness app is being tested to help people with spinal cord injury reduce chronic pain and improve mood and daily functioning.

  NIH research Mayo Clinic Jacksonville · Jacksonville, United States · NIH-11438627

• Minimal digital mindfulness dose for improving attention and stress response

  A study will test how little digital mindfulness training is needed for adults to gain better attention and lower stress responses.

  NIH research Carnegie-Mellon University · Pittsburgh, United States · NIH-11433465

• Promoting better glucose control for gestational diabetes with mindfulness during pregnancy

  A mindfulness-based program called EMPOWER will be developed and tested to help pregnant women with gestational diabetes manage glucose and improve health for both mom and baby.

  NIH research Brown University · Providence, United States · NIH-11425566

• Telehealth Mindful Exercise for Knee Osteoarthritis (TEMPO)

  A 10-week, at-home telehealth program blends mindfulness with exercise to help adults with knee osteoarthritis manage pain and improve function.

  NIH research Boston University (Charles River Campus) · Boston, United States · NIH-11412932

• Mindfulness and breathing feedback to help distressed young adults feel better

  A small program will test a mindfulness app for young adults (18–30) that adds real-time breathing feedback to help reduce anxiety and loneliness.

  NIH research Equa Health, INC. · Pittsburgh, United States · NIH-11411494

• Reinforced mindfulness program to help Hispanic young adults drink less

  A culturally tailored mindfulness-based program is being tested to help Hispanic emerging adults who drink reduce problematic drinking and stay engaged with healthy habits.

  NIH research Florida International University · Miami, United States · NIH-11408706

• Live coaching in a mindfulness app for IBS in young adults

  A digital mindfulness program for IBS in young adults will add live coaching to see if it keeps people engaged and helps reduce symptoms.

  NIH research Equa Health, INC. · Pittsburgh, United States · NIH-11405169

• Mindfulness program in clinics to help mood and diabetes management for teens with Type 1 diabetes

  A practical mindfulness-based program delivered in clinics aims to help mood problems and improve diabetes management for young people with Type 1 diabetes.

  NIH research Children's Research Institute · Washington, United States · NIH-11401454

• LEAP: a youth leadership and mindfulness program to support well-being

  A two-arm study will test whether a 7-week LEAP program that combines leadership training with mindfulness can improve mental, emotional, and behavioral well-being for adolescents aged 12–20.

  NIH research Boston University (Charles River Campus) · Boston, United States · NIH-11395595

• Mindfulness and Self-Hypnosis for Pain in Older Adults

  A non-drug program using mindfulness meditation and self-hypnosis is being studied to help Americans aged 60 and up manage chronic pain.

  NIH research University of Washington · Seattle, United States · NIH-11395520

• Mindfulness meditation with breathing biofeedback

  This project sees if adding real-time breathing feedback to a mindfulness app helps young adults with anxiety, depression, or loneliness stick with the app and feel less distressed.

  NIH research Equa Health, INC. · Pittsburgh, United States · NIH-11393482

• Couple-Based Mindfulness for Metastatic Colorectal Cancer Distress

  A mindfulness program designed for patients with metastatic colorectal cancer and their partners to help them cope with distress and strengthen their relationship.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11393077

• Mindfulness-based help for people on methadone for opioid use

  A program tests an 8-week mindfulness-based therapy added to methadone treatment to help people with opioid use disorder reduce cravings, pain, and emotional distress.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11392281

• Improving physical activity for Latinas using mindfulness

  A program designed for Latina women to help them become more physically active through mindfulness-based strategies delivered remotely.

  NIH research Brown University · Providence, United States · NIH-11387763

• Mindfulness-Based Relapse Prevention via Video Calls for Long-Term Recovery from Alcohol Use Disorder

  A funded program tests video-delivered mindfulness-based relapse prevention to support adults with alcohol use disorder in achieving long-term recovery.

  NIH research University of New Mexico · Albuquerque, United States · NIH-11387731

• Using social networks to improve sleep and mindfulness for older adults in low-income housing

  A woman or man aged 55+ living in low-income housing will get a Sleep Health and Mindfulness program to help sleep better and reduce stress.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11384736

• Motivational Interviewing and Mindfulness-Only Recovery for Tobacco and Other Drug Use in Methadone Treatment

  A new program combines motivational interviewing and mindfulness-based therapy to help people on methadone treatment quit tobacco and other drugs at the same time.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11382249

• Mindfulness program with a multi-method support for college students to handle stress

  A program combines mindfulness training with a smart multi-method support to help college students manage stress and anxiety.

  NIH research Colorado State University · Fort Collins, United States · NIH-11380554

• Mindfulness and self-hypnosis to ease chronic pain in older adults

  This project tests whether mindfulness meditation and self-hypnosis can reduce chronic pain and change brain activity in people aged 60 and older.

  NIH research University of Washington · Seattle, United States · NIH-11378908

• eHealth Mindfulness-based Music Therapy for stem cell transplant patients

  A remote mindfulness-based music therapy program delivered online to people who have had an allogeneic stem cell transplant, aimed at reducing distress and improving quality of life.

  NIH research University of Miami Coral Gables · Coral Gables, United States · NIH-11377516

• Virtual reality mindfulness to reduce aggression in schizophrenia

  A VR mindfulness program is being tested to help reduce aggressive outbursts in people with schizophrenia.

  NIH research Nathan S. Kline Institute for Psych Res · Orangeburg, United States · NIH-11369803

• Mindfulness and motivational coaching to help people on methadone quit smoking and reduce other drug use

  This program offers group mindfulness training plus motivational coaching for people on methadone to help them stop smoking and cut down other drug use.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11364696

• Online Mindfulness-Based Dance/Movement Therapy to boost activity and well-being in older adults

  A new online program combines mindfulness with dance/movement therapy to help adults 65+ stay physically active and feel better overall.

  NIH research Drexel University · Philadelphia, United States · NIH-11359288

• Mindfulness for Sleep and Symptom Relief in Hematologic Cancer Patients During Hospital Stay

  A physician-led mindfulness program delivered via a mobile app during hospitalization aims to improve sleep and reduce fatigue, distress, and pain for patients with blood cancers receiving high-dose chemotherapy.

  NIH research Duke University · Durham, United States · NIH-11349727

• Mindfulness app to support youth in the legal system

  A multi-site, youth-focused trial tests a mindfulness meditation smartphone app to boost wellbeing and reduce distress for young people on probation.

  NIH research University of Illinois at Chicago · Chicago, UNITED STATES · NIH-11349688

• Mindfulness-based brain science to reduce pain and opioid use in chronic back pain

  A study at UC San Diego tests how Mindfulness-Oriented Recovery Enhancement may help people with chronic low back pain use fewer opioids by changing brain activity.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11348866

• Music Therapy and Mindfulness for Stem Cell Transplant Patients

  This project explores how an online program combining music therapy and mindfulness can help patients feel better after a stem cell transplant.

  NIH research University of Miami Coral Gables · Coral Gables, United States · NIH-11347362

• Mindfulness meditation programs for younger breast cancer survivors

  Two short digital mindfulness programs will be offered to younger breast cancer survivors to help reduce depression, fatigue, insomnia, and cancer-related stress.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11329239

• Brief mindfulness training in VA primary care for Veterans

  Four short mindfulness classes offered in VA primary care to help Veterans manage distress, anxiety, and improve overall well‑being.

  NIH research Syracuse VA Medical Center · Syracuse, United States · NIH-11327299

• Ketamine-assisted mindfulness to help people on buprenorphine who keep relapsing

  This project tests whether adding ketamine to a mindfulness-based program (MORE) can help people on buprenorphine who continue to struggle with opioid use.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11323785

Related topics

Quick answers

How many Mindfulness clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in United States (9 trials), Hong Kong (2 trials), Turkey (Türkiye) (1 trial), Taiwan (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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