Mindful-Breath program for people with COPD

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an assessor-blinded, two-arm randomized controlled trial enrolling 60 people with COPD who report moderate stress. Participants are randomized 1:1 to an intervention arm that receives eight weekly 60-minute hybrid group sessions combining mindfulness-based pulmonary rehabilitation and lifestyle modification plus personalized chat-based messaging, ecological momentary interventions, and activity monitoring, or to a control arm that receives a single in-person general education session. Outcomes will be measured before and after the 8-week intervention with blinded assessors and include stress, physical activity, and related wellbeing measures. The program is delivered in Chinese and requires participants to have a mobile device with internet access for the telehealth and messaging components.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age: 50-80 years
* Sex: Male or female
* Education level: Primary or above
* Diagnosis: COPD (Baseline FEV1 \<80% and FEV1/FVC \<70% of predicted normal values)
* Severity of COPD: Stage I to IV
* Group of COPD: Group B, or E, based on 2024 GOLD guideline (36)
* Clinical stability: No acute exacerbation in the past 4 weeks. Patients with recent acute exacerbation in the past 4 weeks will be screened again in subsequent follow-up.
* Moderate stress: PSS score ≥14 (28)
* Access to a mobile device (e.g., a smartphone, tablet, or laptop) with internet connectivity
* Ability to read, communicate, and provide written consent in Chinese.

Exclusion Criteria:

* Engaging in \>60 minutes/week of moderate PA based on American Lung Association guidelines
* Recent or ongoing receipt of other pharmacological/behavioral trials within the past 3 months
* Contraindications or severe comorbidities that may limit full participation (mental diseases, deafness, limb activity disorder, coronary heart disease, arterial aneurysm, uncontrolled hypertension, pregnancy, etc)
* Co-existing respiratory diseases (Asthma/interstitial lung disease/bronchiectasis) or active malignancies
* Very severe COPD requiring long-term oxygen therapy or home non-invasive ventilation

Where it's running

• School of Nursing, The University of Hong Kong, Hong Kong
  Hong Kong, Hong Kong Recruiting

Study contacts

• Study coordinator: Jojo Yan Yan Kwok
• Email: jojoyyk@hku.hk
• Phone: 85239176644

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.