Mindful-Breath program for people with COPD
Effects of a Hybrid, Personalised Mindfulness-optimised Pulmonary Rehabilitation (Mindful-Breath) Programme for Active Living for People With Chronic Obstructive Pulmonary Disease: A Pilot Randomised Controlled Trial
This program will test if a personalized Mindful-Breath telehealth and mindfulness approach helps adults aged 50–80 with COPD feel less stressed and become more active.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 50 Years to 80 Years |
| Sex | All |
| Sponsor | The University of Hong Kong Academic / other |
| Locations | 1 site (Hong Kong) |
| Trial ID | NCT07195838 on ClinicalTrials.gov |
What this trial studies
This is an assessor-blinded, two-arm randomized controlled trial enrolling 60 people with COPD who report moderate stress. Participants are randomized 1:1 to an intervention arm that receives eight weekly 60-minute hybrid group sessions combining mindfulness-based pulmonary rehabilitation and lifestyle modification plus personalized chat-based messaging, ecological momentary interventions, and activity monitoring, or to a control arm that receives a single in-person general education session. Outcomes will be measured before and after the 8-week intervention with blinded assessors and include stress, physical activity, and related wellbeing measures. The program is delivered in Chinese and requires participants to have a mobile device with internet access for the telehealth and messaging components.
Who should consider this trial
Good fit: Ideal candidates are Chinese-speaking adults aged 50–80 with COPD (FEV1 <80% and FEV1/FVC <70%), classified as GOLD group B or E, clinically stable for at least 4 weeks, with moderate stress (PSS ≥14) and access to a mobile device and internet.
Not a fit: Patients who already do >60 minutes/week of moderate physical activity, have recent acute exacerbations, severe comorbidities or cognitive/mental conditions that limit participation, or who cannot use a mobile device or read Chinese are unlikely to benefit from this program.
Why it matters
Potential benefit: If successful, this approach could reduce stress and increase physical activity and overall wellbeing for people with COPD.
How similar studies have performed: Previous mindfulness and pulmonary rehabilitation programs have shown modest benefits for stress and activity in COPD, but combining telehealth, ecological momentary interventions, and personalized chat support is relatively novel and less well tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age: 50-80 years * Sex: Male or female * Education level: Primary or above * Diagnosis: COPD (Baseline FEV1 \<80% and FEV1/FVC \<70% of predicted normal values) * Severity of COPD: Stage I to IV * Group of COPD: Group B, or E, based on 2024 GOLD guideline (36) * Clinical stability: No acute exacerbation in the past 4 weeks. Patients with recent acute exacerbation in the past 4 weeks will be screened again in subsequent follow-up. * Moderate stress: PSS score ≥14 (28) * Access to a mobile device (e.g., a smartphone, tablet, or laptop) with internet connectivity * Ability to read, communicate, and provide written consent in Chinese. Exclusion Criteria: * Engaging in \>60 minutes/week of moderate PA based on American Lung Association guidelines * Recent or ongoing receipt of other pharmacological/behavioral trials within the past 3 months * Contraindications or severe comorbidities that may limit full participation (mental diseases, deafness, limb activity disorder, coronary heart disease, arterial aneurysm, uncontrolled hypertension, pregnancy, etc) * Co-existing respiratory diseases (Asthma/interstitial lung disease/bronchiectasis) or active malignancies * Very severe COPD requiring long-term oxygen therapy or home non-invasive ventilation
Where this trial is running
Hong Kong
- School of Nursing, The University of Hong Kong, Hong Kong — Hong Kong, Hong Kong (Recruiting)
Study contacts
- Study coordinator: Jojo Yan Yan Kwok
- Email: jojoyyk@hku.hk
- Phone: 85239176644
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.