NIH-funded research Sbir 2 grant

Mindfulness and breathing feedback to help distressed young adults feel better

Official title: Mindfulness Meditation and Respiration Biosignal Feedback

Funded at Equa Health, INC. · NIH-11411494 · Data updated 2026-11-12

A small program will test a mindfulness app for young adults (18–30) that adds real-time breathing feedback to help reduce anxiety and loneliness.

More Mindfulness research and trials

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionEqua Health, INC.
NIH-funded
Lab location1 site (Pittsburgh, United States)
Project startJuly 15, 2024
Project endAugust 31, 2027
Funding year2026
Award (this year)$907,396
NIH project number5R44MH134709-03
Project IDNIH-11411494 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are adults 18–30 who are distressed, seeking digital mental health support, and willing to use a mindfulness app.

Less likely to help

Participants without interest in digital mindfulness tools or those who do not engage with the app may see limited benefit.

What this research studies

This project builds on earlier trials of a digital mindfulness app called Equa and tests a new breathing-biosignal feedback feature to help users stay engaged and improve mental health. In Phase I, researchers will validate the respiration feedback tool within the Equa app among distressed young adults. In Phase II, they will evaluate whether the breathing feedback boosts engagement and improves mental health outcomes in this same population. The study uses a 3-arm clinical trial design to compare variants of the app with and without feedback and standard care, conducted by EQUA HEALTH, INC. and led by John David Creswell.

Why it matters

Potential benefit: If successful, the enhanced Equa app could sustain mindfulness practice longer and reduce depressive symptoms, anxiety, and loneliness in young adults.

How similar studies have gone: Previous trials suggest engagement with digital mindfulness programs correlates with better outcomes, but this respiration-feedback addition is a novel enhancement.

Where this research is happening

  • Equa Health, INC.
    Pittsburgh, United States
    Active

Researchers

  • Principal investigator: Creswell, John David — Equa Health, INC.
  • Study coordinator: Creswell, John David

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.