NIH-funded research NIH-funded research

Mindfulness-based Support for Pain and Sleep in Young People with Sickle Cell Disease

Official title: Mindfulness-based Intervention for Pain and Sleep in Adolescents and Young Adults with Sickle Cell Disease

Funded at University of Illinois at Chicago · NIH-11583056 · Data updated 2026-11-12

A digital mindfulness program is being tailored for adolescents and young adults with sickle cell disease to help with pain and sleep and is being tested for practicality and early effectiveness.

More Sickle Cell Disease research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Illinois at Chicago
NIH-funded
Lab location1 site (Chicago, UNITED STATES)
Project startJune 20, 2025
Project endMay 31, 2029
Funding year2026
Award (this year)$248,999
NIH project number4R00NR021195-03
Project IDNIH-11583056 on NIH RePORTER

Who could benefit from this research

Could help

Adolescents and young adults with sickle cell disease who experience chronic pain and sleep disturbances.

Less likely to help

Patients without access to digital devices or with extremely severe symptoms not addressed by MBIs may see limited benefit.

What this research studies

This project focuses on adapting a digital mindfulness program specifically for adolescents and young adults with sickle cell disease to address their chronic pain and sleep problems. The team will test whether the digital program is easy to use, acceptable to users, and shows signs of helping with pain and sleep in a small, early study. Slower, careful development will involve listening to patients to tailor content and delivery, then piloting the program in a way that could lead to a larger trial. The work combines user-centered design with mixed-methods research and randomized elements to gather feedback and preliminary signals of benefit. The ultimate goal is to create a scalable, patient-friendly tool that could improve quality of life for young people living with SCD.

Why it matters

Potential benefit: If successful, patients could experience better pain management and sleep, translating to improved daily functioning and mood.

How similar studies have gone: Prior mindfulness research shows promise in adults; this study adapts the approach for a younger SCD population and is early in development.

Where this research is happening

  • University of Illinois at Chicago
    Chicago, United States
    Active

Researchers

  • Principal investigator: Wi, Dahee — University of Illinois at Chicago
  • Study coordinator: Wi, Dahee

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.