NIH-funded research Sbir 2 grant

Mindfulness meditation with breathing biofeedback

Official title: Mindfulness Meditation and Respiration Biosignal Feedback

Funded at Equa Health, INC. · NIH-11393482 · Data updated 2026-11-12

This project sees if adding real-time breathing feedback to a mindfulness app helps young adults with anxiety, depression, or loneliness stick with the app and feel less distressed.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionEqua Health, INC.
NIH-funded
Lab location1 site (Pittsburgh, United States)
Project startJuly 15, 2024
Project endAugust 31, 2027
Funding year2025
Award (this year)$918,146
NIH project number4R44MH134709-02
Project IDNIH-11393482 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are young adults (about 18–30 years) experiencing anxiety, depressive symptoms, or loneliness who are willing to use a smartphone app and a breathing sensor.

Less likely to help

People outside the target age range, those with severe unmanaged psychiatric illness, or those unwilling to use a smartphone or wearable breathing sensor may not benefit from or be eligible for this project.

What this research studies

You would use the Equa smartphone app and a small breathing sensor that shows your breathing in real time so you can see how your skills change. Participants are randomized into three different groups to compare versions of the app and the new respiration-feedback feature. The project first checks that the breathing-feedback tool works well for distressed young adults, then runs a larger test to see if it increases engagement and improves feelings of loneliness, anxiety, or depression. Your app use, breathing signals, and self-reported mood will be tracked over the follow-up period.

Why it matters

Potential benefit: If successful, this could help young adults stay engaged with mindfulness practice and reduce symptoms of anxiety, depression, and loneliness.

How similar studies have gone: Earlier controlled trials of this digital mindfulness training have shown benefits for mental distress, but adding respiration biosignal feedback is a new feature being tested.

Where this research is happening

  • Equa Health, INC.
    Pittsburgh, United States
    Active

Researchers

  • Principal investigator: Creswell, John David — Equa Health, INC.
  • Study coordinator: Creswell, John David

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.