NIH-funded research Career grant

Couple-Based Mindfulness for Metastatic Colorectal Cancer Distress

Official title: Addressing Colorectal Cancer-Related Distress: Developing and Evaluating a Couple-Based Mindfulness Intervention

Funded at University of Colorado Denver · NIH-11393077 · Data updated 2026-11-12

A mindfulness program designed for patients with metastatic colorectal cancer and their partners to help them cope with distress and strengthen their relationship.

More Colorectal Cancer research and trials

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver
NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project startAugust 12, 2022
Project endAugust 31, 2027
Funding year2026
Award (this year)$169,512
NIH project number5K08CA267313-06
Project IDNIH-11393077 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are adults with metastatic colorectal cancer and their intimate partners.

Less likely to help

Patients or partners not experiencing distress or who have limited access to video conferencing may experience less direct benefit.

What this research studies

This grant aims to create a four-session mindfulness program delivered by video for couples facing metastatic colorectal cancer. It starts by gathering input from 12 couples and 12 clinicians to tailor the content to real needs, then develops the program called MIND-Together. The team will pilot the intervention and refine it based on feedback to support mindful coping and reduce distress for both patients and their partners. The project focuses on practical, relationship-centered strategies that can be accessed remotely.

Why it matters

Potential benefit: If successful, couples facing mCRC could experience lower distress and better emotional connection, even during challenging treatments.

How similar studies have gone: Past studies show mindfulness can reduce distress in cancer patients and partners, but this couple-focused adaptation for mCRC is novel.

Where this research is happening

  • University of Colorado Denver
    Aurora, United States
    Active

Researchers

  • Principal investigator: Zimmaro, Lauren a. — University of Colorado Denver
  • Study coordinator: Zimmaro, Lauren a.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.