Condition

Prediabetic State clinical trials and research

• 17Clinical trials
• 16Countries

Newest Prediabetic State clinical trials

All recruiting trials (17)

• Orforglipron in adults with overweight at risk for obesity-related problems

  This study tests whether orforglipron can help people who are overweight and have early signs of metabolic or cardiovascular risk.

  Recruiting at 88 sites Phase 3 Eli Lilly and Company · Anniston, Alabama and 179 other locations · NCT07794579

• High-Intensity Interval Training vs. Continuous Endurance Training in Prediabetes

  This study tests whether short bursts of intense exercise or steady, longer workouts can improve blood sugar control and fitness in people with prediabetes.

  Recruiting Riphah International University · Lahore, Punjab Province · NCT07713030

• Metabolic Health Trajectories in Overweight Chinese Adults

  This observational study follows overweight and obese Chinese adults to see how metabolic health changes over five years and whether people stay healthy, develop diabetes, or have complications.

  Recruiting Zhujiang Hospital · Guangzhou, Guangdong · NCT07584330

• Lowering insulin to reduce liver fat production

  This study will try a short course of diazoxide to lower insulin and see if it reduces the liver's creation of new fat in adults with obesity, insulin resistance, and MASLD.

  Recruiting Phase 1 Columbia University · New York, New York · NCT07403604

• Hands-on nutrition demonstrations added to the Diabetes Prevention Program for people with prediabetes

  This project will test whether adding a 7-week series of healthy cooking and nutrition demos to the Diabetes Prevention Program helps adults at risk for prediabetes stay engaged and put healthy eating into daily life.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT06897982

• Effect of Olive Pomace Oil on Blood Sugar Levels

  This study is testing if adding olive pomace oil to meals can help people with type 2 diabetes or those at risk manage their blood sugar levels better.

  Recruiting Instituto de Ciencia y Tecnología de Alimentos y Nutrición · Madrid, Madrid · NCT06723886

• Couple-based lifestyle intervention to prevent type 2 diabetes

  This study is testing if a lifestyle program for couples can help high-risk adults prevent type 2 diabetes by encouraging healthy changes together.

  Recruiting University of Utah · Salt Lake City, Utah · NCT06690788

• Heat pads versus high-intensity interval training to improve muscle and blood sugar in older adults with prediabetes

  This project will test whether daily thigh heat pads can improve muscle health, physical function, and blood sugar control as well as high-intensity interval training in older adults with prediabetes.

  Recruiting Texas Tech University · Lubbock, Texas · NCT06580964

• Preventing type 2 diabetes in high-risk adults in Brazil

  This study is testing a diabetes prevention program in Brazil to see if it can help high-risk adults avoid developing type 2 diabetes over three years.

  Recruiting at 2 sites Beneficência Portuguesa de São Paulo · Goiânia, Goiás and 1 other locations · NCT06426277

• Investigating insulin resistance using alpelisib in adults

  This study is testing if a drug called alpelisib can help us understand how insulin works in healthy adults compared to those at risk for type 2 diabetes.

  Recruiting Phase 1 Columbia University · New York, New York · NCT06354088

• Eating window timing to improve blood sugar in adults with obesity and type 2 diabetes or at risk

  This study tests whether eating only during one of three nine-hour daily windows can improve blood sugar control in adults with obesity who have or are at risk for type 2 diabetes.

  Recruiting University of Toronto · Toronto, Ontario · NCT06118931

• Zinc supplementation's effect on blood sugar levels in prediabetics

  This study is testing if taking zinc supplements can help lower blood sugar levels in people with prediabetes.

  Recruiting Phase 4 University of Maryland, Baltimore · Lancaster, Pennsylvania · NCT05835037

• Effects of Exercise on Fat Metabolism in Postmenopausal Women

  This study tests whether resistance training or endurance training helps postmenopausal women who are obese and prediabetic improve their fat metabolism over 12 weeks.

  Recruiting Florida State University · Tallahassee, Florida · NCT05351476

• Investigating how genetics affect response to oral semaglutide in prediabetes and obesity

  This study is testing how genetics affect how well people with prediabetes and obesity respond to a three-month treatment with oral semaglutide.

  Recruiting Medical University of Bialystok · Bialystok, Podlaskie Voivodeship · NCT05340868

• Improving blood sugar control through timed high-intensity exercise

  This study tests if doing high-intensity exercise at certain times of the day can help people with prediabetes better control their blood sugar and improve their insulin sensitivity.

  Recruiting Université de Sherbrooke · Sherbrooke, Quebec · NCT05123963

• Observational study on Alzheimer's disease and cognitive impairment

  This study is trying to gather important information and samples from adults aged 55 and older, with or without memory problems, to help improve early detection and treatment of Alzheimer's disease.

  Recruiting Wake Forest University Health Sciences · Winston-Salem, North Carolina · NCT03140865

• Using Metformin to Reduce Heart Risks in Veterans with Prediabetes

  This study tests if the diabetes drug metformin can help reduce the risk of heart attacks, strokes, and death in Veterans with prediabetes and heart disease.

  Recruiting at 37 sites Phase 4 VA Office of Research and Development · Phoenix, Arizona and 39 other locations · NCT02915198

Related topics

Quick answers

How many Prediabetic State clinical trials are recruiting right now?

17, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 16 countries. The most sites are in United States (10 trials), Canada (2 trials), China (2 trials), Spain (2 trials), Brazil (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 2, Phase 4: 2, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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