Condition

Malignant Melanoma clinical trials and research

• 19Clinical trials
• 12Countries

Newest Malignant Melanoma clinical trials

All recruiting trials (19)

• Social prescriptions and micro-learning to improve cancer care

  This study tests a multicomponent program using social prescriptions and short online learning to help cancer patients and their chosen support persons in Germany.

  Recruiting University of Regensburg · Augsburg, Bavaria and 7 other locations · NCT07788729

• TCC1727 combined with other cancer medicines for adults with advanced solid tumors

  This phase Ib/II trial tests TCC1727 given with benmelstobart, olaparib, or topotecan in adults with advanced solid tumors to find safe doses and see if the combinations help control tumors.

  Recruiting Phase 1/2 Beijing Tide Pharmaceutical Co., Ltd · Beijing, Beijing Municipality and 2 other locations · NCT07371663

• Regular supervised exercise to reduce symptoms in melanoma

  This trial tests whether a 12-week supervised exercise program can reduce fatigue and improve quality of life for adults with stage IIb–IV melanoma who are receiving immunotherapy or targeted therapy.

  Recruiting Universität Duisburg-Essen · Essen · NCT06985056

• Video consultations for cancer treatment recommendations

  This study is testing if video consultations can help patients with malignant melanoma get better treatment recommendations by connecting them with cancer experts from different specialties, no matter where they live.

  Recruiting University Hospital Muenster · Bonn and 2 other locations · NCT06980740

• Testing a new antibody treatment for advanced solid tumors and liver cancer

  This study is testing a new antibody treatment for people with advanced solid tumors and liver cancer to see if it is safe and how well it works.

  Recruiting at 5 sites Phase 1 Chiome Bioscience Inc. · Kashiwa, Chiba and 4 other locations · NCT06636435

• Using PSMA-PET to guide melanoma surgery planning

  We will see if a PSMA PET/CT scan can find melanoma spread more clearly than the standard FDG PET/CT in adults with palpable lymph nodes or limited metastatic melanoma who are scheduled for surgery.

  Recruiting Phase 2 Royal Marsden NHS Foundation Trust · London · NCT06560905

• Evaluating LB-LR1109 for treating solid tumors

  This study is testing a new treatment called LB-LR1109 to see how safe it is and how well it works for people with advanced solid tumors that can't be treated with standard options.

  Recruiting Phase 1 LG Chem · Fairfax, Virginia · NCT06332755

• Intratumoral injection of GM103 for advanced solid tumors

  This study is testing a new virus treatment called GM103, alone and with another drug, to see if it can help people with advanced solid tumors that are hard to treat.

  Recruiting Phase 1/2 GeneMedicine Co., Ltd. · Goyang-si, Gyeonggi-do and 3 other locations · NCT06265025

• AMT-253 treatment for advanced solid tumors

  This study is testing a new treatment called AMT-253 to see if it can help people with advanced melanoma and other solid tumors who have run out of other treatment options.

  Recruiting Phase 1/2 Multitude Therapeutics Inc. · Beijing, Beijing Municipality · NCT06209580

• Using fecal microbiota transplantation to treat diarrhea and colitis from cancer immunotherapy

  This study tests if a stool transplant can help people with melanoma or kidney cancer who are having severe diarrhea and colitis from their immunotherapy treatment.

  Recruiting University of Aarhus · Aarhus N · NCT06206707

• Testing CTX-8371 in patients with advanced cancers

  This study is testing a new treatment called CTX-8371 in patients with advanced cancers to see if it can help them when other treatments haven't worked.

  Recruiting at 11 sites Phase 1 Compass Therapeutics · Birmingham, Alabama and 11 other locations · NCT06150664

• Carbon ion radiation therapy for treating mucous melanomas in the female lower genital tract

  This study is testing if carbon ion radiation therapy can help women with non-metastatic mucosal melanoma in the lower genital tract who can't have surgery, to see if it works better than standard treatments.

  Recruiting CNAO National Center of Oncological Hadrontherapy · Pavia · NCT05478876

• RAPA-201 therapy for solid tumors

  This study is testing a new type of immune therapy using specially modified T cells from patients' own blood to see if it can help people with advanced solid tumors that haven't improved with other treatments.

  Recruiting Phase 1/2 Rapa Therapeutics LLC · Hackensack, New Jersey · NCT05144698

• Exploring the gut microbiome's role in cancer treatment response

  This study is testing how the bacteria in the gut might affect how well cancer patients respond to a specific type of treatment called immune checkpoint inhibitors.

  Recruiting VastBiome · Elizabethtown, Kentucky · NCT05037825

• Intradermal treatment for advanced melanoma

  This study is testing a new immune booster called IMO-2125 to see if it helps people with advanced melanoma feel better after surgery.

  Recruiting Phase 2 Amsterdam UMC, location VUmc · Amsterdam · NCT04126876

• Treatment for melanoma that has spread to the brain using immune therapy and steroids

  This study is testing if a combination of immune therapies can help patients with melanoma that has spread to the brain while they are also taking steroids.

  Recruiting Phase 2 Herlev Hospital · Herlev, Capital Region and 2 other locations · NCT03563729

• Assessing the role of imaging in follow-up after surgery for high-risk melanoma

  This study is testing if adding imaging tests like CT or PET scans during follow-up after surgery can help people with high-risk melanoma live longer compared to just regular doctor visits.

  Recruiting at 15 sites Uppsala University · Borås and 19 other locations · NCT03116412

• Follow-up of patients with advanced melanoma

  This study is tracking patients with advanced melanoma to see how different factors affect their treatment outcomes and to understand the costs and side effects of new therapies.

  Recruiting at 20 sites Assistance Publique - Hôpitaux de Paris · Amiens and 26 other locations · NCT02828202

• Modified melanoma cell-line vaccine for people at high risk of recurrence or with a small amount of remaining disease

  This will test a modified melanoma cell-line vaccine that boosts immune recognition to see if it helps people who are disease-free after surgery or who have only a small amount of remaining melanoma but are at high risk of recurrence.

  Recruiting Phase 1/2 Hadassah Medical Organization · Jerusalem · NCT01898039

Related topics

Quick answers

How many Malignant Melanoma clinical trials are recruiting right now?

19, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 12 countries. The most sites are in United States (4 trials), Germany (3 trials), China (2 trials), Denmark (2 trials), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 5, Phase 2: 3, Phase 1: 3. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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