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Lung Cancer, Non-Small Cell clinical trials and research

• 27Clinical trials
• 9Countries

Newest Lung Cancer, Non-Small Cell clinical trials

All recruiting trials (27)

• Personalized exercise plan for cancer survivors

  This study tests a personalized, physician-guided exercise program for adults who have completed cancer treatment, to see if a safe, structured plan can be implemented in routine care.

  Recruiting Kaohsiung Medical University Chung-Ho Memorial Hospital · Kaohsiung, Taiwan · NCT07751783

• Abdominal pressure device to control breathing during stereotactic radiotherapy for peripheral non-small cell lung cancer

  This project tries an abdominal pressure device to reduce breathing-related tumor movement during stereotactic radiotherapy for people with solitary peripheral non-small cell lung cancer.

  Recruiting Tianjin Medical University Cancer Institute and Hospital · Tianjin · NCT07561567

• Combining nutrition checks and muscle measurements to predict outcomes after lung cancer surgery

  This project will test whether combining nutrition tests and muscle scans can predict recovery, complications, and short-term outcomes in adults having lung cancer surgery.

  Recruiting Ondokuz Mayıs University · Samsun, Samsun · NCT07500376

• Ivonescimab alone or with carboplatin/pemetrexed for advanced NSCLC with actionable alterations

  This trial tests if ivonescimab, alone or with chemotherapy, can shrink tumors in advanced NSCLC patients who have actionable genomic alterations after prior targeted therapies.

  Recruiting at 2 sites Phase 2 Massachusetts General Hospital · Boston, Massachusetts and 2 other locations · NCT07405190

• Ivonescimab alone or with carboplatin/pemetrexed for advanced NSCLC with actionable alterations

  This trial tests if ivonescimab, alone or with chemotherapy, can shrink tumors in advanced NSCLC patients who have actionable genomic alterations after prior targeted therapies.

  Recruiting at 2 sites Phase 2 Massachusetts General Hospital · Boston, Massachusetts and 2 other locations · NCT07405190

• Ivonescimab alone or with carboplatin/pemetrexed for advanced NSCLC with actionable alterations

  This trial tests if ivonescimab, alone or with chemotherapy, can shrink tumors in advanced NSCLC patients who have actionable genomic alterations after prior targeted therapies.

  Recruiting at 2 sites Phase 2 Massachusetts General Hospital · Boston, Massachusetts and 2 other locations · NCT07405190

• SL-28 for Advanced Solid Tumours

  A new allogeneic cell therapy called SL-28 is being tested in adults with advanced solid tumors to see if it is safe and can help shrink tumors.

  Recruiting Phase 1/2 Second Life Therapeutics · Sydney, New South Wales and 2 other locations · NCT07341737

• Phase II test of SKB571 for advanced non-small cell lung cancer

  This study will test SKB571 given alone in adults with advanced non-small cell lung cancer to see if it is safe and can shrink tumors.

  Recruiting Phase 2 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. · Guangzhou and 1 other locations · NCT07230405

• Support for Veterans with lung cancer.

  This study will test whether weekly phone support from a trained lay health worker can improve quality of life for Veterans who are newly diagnosed with lung cancer or who finished treatment within the past year.

  Recruiting Palo Alto Veterans Institute for Research · Palo Alto, California · NCT07219251

• Exercise and the tumor microenvironment in non-small cell lung cancer

  This project will test whether a pre-surgery exercise program changes the tumor microenvironment and improves peri-operative outcomes for people with early-stage non-small cell lung cancer.

  Recruiting University of Arizona · Tucson, Arizona · NCT07216209

• IBI351 with cetuximab β for previously untreated advanced KRAS G12C non-small cell lung cancer

  This trial tests whether combining IBI351 with cetuximab β helps people with untreated advanced non-small cell lung cancer that has a KRAS G12C mutation.

  Recruiting at 5 sites Phase 2 Guangdong Association of Clinical Trials · Guangzhou, Guangdong and 6 other locations · NCT07198841

• Neoadjuvant immunotherapy before surgery for non-small cell lung cancer

  This project will see if giving immunotherapy before surgery helps adults with non‑small cell lung cancer and whether pneumonectomy, lobectomy, or non‑surgical treatments lead to better long‑term outcomes.

  Recruiting Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Beijing · NCT07166003

• MBRC-201 dose-finding and safety in advanced metastatic solid tumors

  We will test different doses of an antibody-drug conjugate called MBRC-201 in adults whose advanced metastatic cancers (including prostate, breast, colorectal, lung, and pancreatic cancer) have not responded to standard treatments.

  Recruiting at 7 sites Phase 1/2 MBrace Therapeutics · San Francisco, California and 6 other locations · NCT07145255

• Analysis of circulating tumor markers in blood in lung cancer patients

  This study tests whether blood-based tumor markers can help understand and monitor lung cancer in adults to complement tissue tests.

  Recruiting Institut du Cancer de Montpellier - Val d'Aurelle · Montpellier, France · NCT07060950

• Detecting lung cancer through blood tests using DNA analysis

  This study is testing a new blood test that looks for signs of lung cancer by analyzing DNA from dying cancer cells to see if it can help with early detection and treatment.

  Recruiting JaxBio Ltd · Ramat Gan · NCT06963307

• Combination of nivolumab and ipilimumab before surgery for lung cancer

  This study is testing a combination of two immunotherapy drugs, nivolumab and ipilimumab, before surgery to see if it helps people with advanced lung cancer do better than traditional treatments.

  Recruiting Phase 2 The First Affiliated Hospital of Guangzhou Medical University · Guangzhou · NCT06926790

• Using liquid biopsy from EBUS-TBNA fluid to diagnose lung cancer

  This study is testing if analyzing fluid from a specific lung procedure can help diagnose lung cancer in patients who are suspected to have it but have had negative test results.

  Recruiting Barzilai Medical Center · Ashkelon · NCT06889467

• Comparing standard care to early palliative care for advanced lung cancer patients

  This study tests if adding early palliative care to standard treatment can help improve the quality of life and survival for people with advanced lung cancer.

  Recruiting Mahidol University · Bangkok · NCT06786468

• Combining AK112 with chemotherapy for advanced lung cancer

  This study is testing if a new treatment called AK112, when combined with chemotherapy, can help people with advanced lung cancer feel better and improve their health.

  Recruiting Phase 2 Sichuan University · Chengdu, Sichuan · NCT06769295

• Investigating KQB365 for treating advanced solid tumors

  This study tests if a new treatment called KQB365, alone or with another drug, can help adults with advanced solid tumors that have specific genetic mutations.

  Recruiting at 11 sites Phase 1 Kumquat Biosciences Inc. · Phoenix, Arizona and 10 other locations · NCT06720987

• Evaluating sleeve lobectomy techniques for lung cancer treatment

  This study is testing if a robotic-assisted surgery for lung cancer can help patients live longer and have better recovery compared to a different type of minimally invasive surgery.

  Recruiting at 3 sites Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou and 2 other locations · NCT06687408

• Using tislelizumab and chemotherapy for lung cancer surgery

  This study is testing if combining a new drug called tislelizumab with chemotherapy can help people with a specific type of lung cancer respond better before surgery.

  Recruiting Phase 2 Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT06659042

• Radiolabelled Nectin-4 Targeted LMW Probe PET/CT in Patients With Lung Lesions

  This study is testing a new imaging method using a special probe to see if it can help doctors better identify lung lesions in patients.

  Recruiting Peking University Cancer Hospital & Institute · Beijing, Beijing Municipality · NCT06648317

• Combining TIL Therapy and Pembrolizumab for Advanced Lung Cancer

  This study is testing a new treatment that combines a special type of immune cells from patients' tumors with an existing cancer drug to see if it helps people with advanced lung cancer feel better and live longer.

  Recruiting Phase 1/2 Essen Biotech · Beijing, Beijing Municipality · NCT06538012

• Treatment of advanced lung cancer using KB707

  This study is testing a new treatment called KB707 to see if it can help adults with advanced lung cancer by boosting their immune response, especially for those who haven't had success with standard therapies.

  Recruiting at 10 sites Phase 1/2 Krystal Biotech, Inc. · Dothan, Alabama and 13 other locations · NCT06228326

• Tracking lung cancer evolution through therapy

  This study is trying to see how lung cancer changes during treatment in people with different types of the disease by collecting health information and samples over two years.

  Recruiting University College, London · London · NCT05628376

• Understanding why some lung cancer patients don't respond to new treatments

  This study is trying to understand why some patients with advanced lung cancer don't respond to new treatments so that doctors can better tailor therapies to help them.

  Recruiting Second Xiangya Hospital of Central South University · Changsha, Hunan · NCT05598528

Related topics

Quick answers

How many Lung Cancer, Non-Small Cell clinical trials are recruiting right now?

27, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in China (11 trials), United States (8 trials), Israel (2 trials), Turkey (Türkiye) (1 trial), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 8, Phase 1/2: 4, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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