Clinical trial Recruiting at 3 sites Observational Ages 18 and up

Evaluating sleeve lobectomy techniques for lung cancer treatment

Official title: Sleeve Lobectomy for Lung Cancer in Minimally Invasive Surgical Techniques: a Multicenter Cohort Study

Run by Second Affiliated Hospital, Zhejiang University, School of Medicine · NCT06687408 · Data updated 2026-11-12

This study is testing if a robotic-assisted surgery for lung cancer can help patients live longer and have better recovery compared to a different type of minimally invasive surgery.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment450 (estimated)
SponsorSecond Affiliated Hospital, Zhejiang University, School of Medicine
Academic / other
Locations3 sites (Hangzhou and 2 other locations)
StatusRecruiting
StartedMarch 1, 2025
Main results expectedDecember 31, 2027
Study endsDecember 31, 2027
Registry record updatedApril 24, 2026
Trial IDNCT06687408 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults aged 18 and older with clinically suspected NSCLC who are likely to undergo sleeve lobectomy.

Probably not a fit

Patients who cannot undergo surgical resection due to contraindications or those with a different type of lung cancer may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter observational study aims to assess the long-term survival and perioperative outcomes of sleeve lobectomy performed using robotic-assisted thoracic surgery (RATS) compared to video-assisted thoracic surgery (VATS) for patients with centrally located non-small cell lung cancer (NSCLC). The study will analyze data from participants who underwent these minimally invasive surgical techniques between January 2015 and September 2024. By focusing on a high-volume cohort, the researchers seek to determine if RATS offers similar or improved outcomes compared to VATS in this patient population.

Why it matters

Potential benefit: If successful, this study could provide insights into the most effective surgical approach for improving survival rates in lung cancer patients.

How similar studies have gone: Previous studies have shown comparable outcomes between RATS and VATS, but this study aims to validate those findings in a larger, multicenter cohort.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years;
* Clinically suspected lung cancer with a high likelihood of undergoing sleeve lobectomy;
* Postoperative histopathological diagnosis confirms non-small cell lung cancer (NSCLC);
* No history of malignancy within the past 5 years;
* Signed informed consent agreeing to participate in this study.

Exclusion Criteria:

* Unable to undergo surgical resection due to surgical contraindications;
* Postoperative pathology does not confirm non-small cell lung cancer (NSCLC), including but not limited to benign lesions, small cell lung cancer, metastatic tumors, or an insufficient or indeterminate histopathology report;
* History of malignancy within the past 5 years;
* Unable to obtain follow-up data;
* Refusal to sign the informed consent or withdrawal of consent.

Where it's running

  • The Second Affiliated Hospital Zhejiang University School of Medicine
    Hangzhou, China
    Recruiting
  • Sir Run Run Shaw Hospital, Medical College, Zhejiang University
    Hangzhou, China
    Recruiting
  • Shanghai Chest Hospital, Shanghai Jiao Tong University
    Shanghai, China
    Recruiting

Study contacts

  • Principal investigator: Haifeng Shen, M.D. — Second Affiliated Hospital, Zhejiang University, School of Medicine
  • Study coordinator: Haifeng Shen, M.D.
  • Email: shenhaifeng@zju.edu.cn
  • Phone: +86 13634197989

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.