Evaluating sleeve lobectomy techniques for lung cancer treatment
Sleeve Lobectomy for Lung Cancer in Minimally Invasive Surgical Techniques: a Multicenter Cohort Study
This study is testing if a robotic-assisted surgery for lung cancer can help patients live longer and have better recovery compared to a different type of minimally invasive surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 450 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Second Affiliated Hospital, School of Medicine, Zhejiang University Academic / other |
| Locations | 3 sites (Hangzhou and 2 other locations) |
| Trial ID | NCT06687408 on ClinicalTrials.gov |
What this trial studies
This multicenter observational study aims to assess the long-term survival and perioperative outcomes of sleeve lobectomy performed using robotic-assisted thoracic surgery (RATS) compared to video-assisted thoracic surgery (VATS) for patients with centrally located non-small cell lung cancer (NSCLC). The study will analyze data from participants who underwent these minimally invasive surgical techniques between January 2015 and September 2024. By focusing on a high-volume cohort, the researchers seek to determine if RATS offers similar or improved outcomes compared to VATS in this patient population.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older with clinically suspected NSCLC who are likely to undergo sleeve lobectomy.
Not a fit: Patients who cannot undergo surgical resection due to contraindications or those with a different type of lung cancer may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into the most effective surgical approach for improving survival rates in lung cancer patients.
How similar studies have performed: Previous studies have shown comparable outcomes between RATS and VATS, but this study aims to validate those findings in a larger, multicenter cohort.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years; * Clinically suspected lung cancer with a high likelihood of undergoing sleeve lobectomy; * Postoperative histopathological diagnosis confirms non-small cell lung cancer (NSCLC); * No history of malignancy within the past 5 years; * Signed informed consent agreeing to participate in this study. Exclusion Criteria: * Unable to undergo surgical resection due to surgical contraindications; * Postoperative pathology does not confirm non-small cell lung cancer (NSCLC), including but not limited to benign lesions, small cell lung cancer, metastatic tumors, or an insufficient or indeterminate histopathology report; * History of malignancy within the past 5 years; * Unable to obtain follow-up data; * Refusal to sign the informed consent or withdrawal of consent.
Where this trial is running
Hangzhou and 2 other locations
- The Second Affiliated Hospital Zhejiang University School of Medicine — Hangzhou, China (Recruiting)
- Sir Run Run Shaw Hospital, Medical College, Zhejiang University — Hangzhou, China (Recruiting)
- Shanghai Chest Hospital, Shanghai Jiao Tong University — Shanghai, China (Recruiting)
Study contacts
- Principal investigator: Haifeng Shen, M.D. — Second Affiliated Hospital, School of Medicine, Zhejiang University
- Study coordinator: Haifeng Shen, M.D.
- Email: shenhaifeng@zju.edu.cn
- Phone: +86 13634197989
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.