Comparing standard care to early palliative care for advanced lung cancer patients
Official title: Randomized Controlled Trial of Standard Care With or Without Early Palliative Care Provided by Palliative Care Specialist in Advanced Non-small Cell Lung Cancer Patients
Run by Mahidol University · NCT06786468 · Data updated 2026-11-12
This study tests if adding early palliative care to standard treatment can help improve the quality of life and survival for people with advanced lung cancer.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 104 (estimated) |
| Sponsor | Mahidol University Academic / other |
| Drugs / interventions | chemotherapy, immunotherapy |
| Locations | 1 site (Bangkok) |
| Status | Recruiting |
| Started | April 2, 2024 |
| Main results expected | April 2026 |
| Study ends | April 2027 |
| Registry record updated | January 22, 2025 |
| Trial ID | NCT06786468 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older with pathologically confirmed advanced non-small cell lung cancer who are about to start systemic treatment.
✕Probably not a fit
Patients who have previously received systemic treatment for advanced lung cancer may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the impact of early palliative care provided by specialists on the quality of life and survival of patients with advanced non-small cell lung cancer. Participants will be randomly assigned to receive either standard oncology care or early palliative care alongside their treatment. The early palliative care group will attend monthly palliative care appointments for the first three months, while the control group will only attend oncology appointments. Patients will complete various questionnaires to assess their quality of life, mental health, and pain levels throughout the study.
Why it matters
Potential benefit: If successful, this study could enhance the quality of life and potentially improve survival rates for patients with advanced lung cancer.
How similar studies have gone: Previous studies have shown that early palliative care can improve outcomes for advanced lung cancer patients, but this study aims to evaluate its effectiveness in the context of modern treatment options.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age at least 18 years old * Pathologically confirmed advanced non-small cell lung cancer * Plan to receive systemic treatment for lung cancer within three weeks * ECOG performance status 0-2 with estimated life expectancy \> 24 weeks * Having at least 4 scores according to Edmonton Symptom Assessment System (ESAS) * Able to complete the questionnaires Exclusion Criteria: * Had received systemic treatment for advanced lung cancer before
Where it's running
-
Siriraj Hospital
Bangkok, Thailand Recruiting
Study contacts
- Principal investigator: Lucksamon Thamlikitkul, MD, PhD — Mahidol University
- Study coordinator: Lucksamon Thamlikitkul, MD, PhD
- Email: lucksamon.tha@mahidol.edu
- Phone: +6624194489
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.