Condition

Lower Urinary Tract Symptoms clinical trials and research

• 17Clinical trials
• 5NIH research projects
• 26Countries

Newest Lower Urinary Tract Symptoms clinical trials

All recruiting trials (17)

• Tamsulosin alone vs. tamsulosin with tadalafil for troublesome urinary symptoms from enlarged prostate

  This study tests whether adding tadalafil to tamsulosin helps men with BPH see better urinary symptoms and quality of life, using two tadalafil doses over 12 weeks.

  Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT07722884

• Water Vapor Therapy vs Ejaculation-Sparing Enucleation for Benign Prostatic Hyperplasia

  This study tests whether Water Vapor Thermal Therapy (Rezum) or an ejaculation-sparing enucleation procedure better helps sexually active men with bothersome BPH symptoms.

  Recruiting Beni-Suef University · Banī Suwayf, Beni Suweif Governorate · NCT07648888

• Water Vapor Therapy versus Ejaculation-Preserving HoLEP for Benign Prostatic Hyperplasia

  This study compares Rezum water vapor therapy to ejaculation-preserving HoLEP in sexually active men with moderate-to-severe symptoms from BPH to see which preserves ejaculation better while easing urinary symptoms.

  Recruiting Beni-Suef University · Banī Suwayf, Beni Suweif Governorate · NCT07648875

• Ejaculation-Preserving Bipolar Prostate Enucleation for BPH

  This randomized trial tests whether a modified ejaculation-preserving bipolar TUEP can maintain ejaculation while still relieving urinary symptoms in sexually active men with BPH who didn’t improve with meds.

  Recruiting Beni-Suef University · Banī Suwayf, Beni Suweif Governorate · NCT07629479

• Melatonin and Solifenacin for stent-related symptoms after ureteroscopy

  This study tests whether solifenacin, melatonin, or both can reduce stent-related urinary symptoms and improve sleep after ureteroscopic stone treatment.

  Recruiting Phase 2 Beni-Suef University · Banī Suwayf, BeniSuef · NCT07617922

• Urine, perineal, and stool microbiota in children and adolescents

  We will test whether the bacteria in voided urine, around the genitals, and in stool differ between children with overactive bladder or daytime wetting and healthy children of the same age and gender.

  Recruiting at 2 sites Aalborg University Hospital · Aalborg and 3 other locations · NCT07535619

• Effect of Bariatric Surgery on Urinary Symptoms

  This study is testing how bariatric surgery affects urinary symptoms in people with severe obesity compared to those who don't have the surgery.

  Recruiting Chinese University of Hong Kong · Hong Kong · NCT06464822

• Understanding lower urinary tract symptoms in Chinese men

  This study looks at how common lower urinary tract symptoms are in Chinese men and what factors might be linked to these symptoms, while also checking how many men are getting treated for them.

  Recruiting Chinese PLA General Hospital · Beijing · NCT06352736

• Ultrasound imaging to assess lower urinary tract symptoms

  This study is testing a new, cost-effective ultrasound method to see how well it can measure bladder function in men with lower urinary tract symptoms and benign prostatic hyperplasia.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06323109

• Effect of stem cell transplantation on urinary function in MS patients

  This study looks at whether stem cell transplantation can improve urinary problems and quality of life for people with multiple sclerosis compared to those receiving other treatments.

  Recruiting University Hospital Ostrava · Ostrava, Moravian-Silesian Region · NCT06218927

• Investigating brain activity in children with overactive bladder and urinary incontinence

  This study is testing how brain activity differs in children with overactive bladder and urinary incontinence compared to healthy kids, to see if a new treatment can help improve their bladder control.

  Recruiting Aalborg University Hospital · Aalborg and 3 other locations · NCT05989646

• Using Tadalafil to Improve Urinary and Sexual Function After Prostate Surgery

  This study is testing if Tadalafil can help men over 40 improve their urinary and sexual function after having prostate surgery for an enlarged prostate.

  Recruiting Phase 2/3 Mansoura University · Al Mansurah, Dakahlia Governorate · NCT05955001

• Comparing two treatments for severe urinary symptoms in men with prostate enlargement

  This study is testing whether a new heat treatment or a blood vessel blocking procedure can help men with prostate enlargement feel better and improve their urinary symptoms.

  Recruiting at 3 sites Copenhagen University Hospital, Rigshospitalet · Copenhagen, Copenhagen N and 2 other locations · NCT05686525

• Global registry for benign prostatic hyperplasia treatments

  This study is collecting information from men with benign prostatic hyperplasia to see how different treatments work and to help improve future care.

  Recruiting at 22 sites Société Internationale d'Urologie · Los Angeles, California and 29 other locations · NCT05543200

• Daily transcutaneous tibial nerve stimulation to improve bladder emptying in multiple sclerosis

  This trial will test whether daily transcutaneous tibial neurostimulation for 30 minutes over 12 weeks can improve bladder emptying in people with multiple sclerosis who use clean intermittent self-catheterization.

  Recruiting University Hospital, Lille · Lille · NCT04573673

• Holmium laser treatment for prostate cancer patients with urinary symptoms

  This study tests if using a special laser treatment for prostate issues can help men with prostate cancer who have bothersome urinary symptoms feel better before they start radiation therapy.

  Recruiting University of Kansas Medical Center · Kansas City, Kansas · NCT03802851

• Registry for assessing treatments of benign prostatic hyperplasia

  This study is collecting information to see how well different treatments for enlarged prostate symptoms work, comparing new options with traditional ones for men aged 18 and older.

  Recruiting Cantonal Hospital of St. Gallen · Sankt Gallen, Canton of St. Gallen · NCT03521648

NIH-funded research (5)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Nitric Oxide Pathway as a Target for Male BPH and LUTS in Aging

  A patient-facing program exploring how a nitric oxide pathway might help men with aging-related urinary symptoms from enlarged prostate.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11365206

• Understanding a key pathway for bladder issues in aging men

  This research explores a specific body pathway to find new ways to help aging men with common bladder problems like frequent urination and difficulty emptying their bladder.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11170437

• Investigating a new treatment pathway for bladder issues in aging men

  This study is looking at how a specific pathway in the body can help improve treatment for men dealing with bladder issues caused by an enlarged prostate, especially as they get older, and aims to find new options that work better and have fewer side effects.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-10910129

• Investigating how life stress affects bladder health and urinary symptoms

  This study looks at how different life stresses can affect bladder health and urinary issues in both men and women, aiming to find ways to keep your bladder healthy and prevent problems.

  NIH research University of Minnesota · Minneapolis, United States · NIH-10906163

• Investigating the role of urinary bacteria and inflammation in bladder symptoms

  This study is looking at how the tiny germs in your urinary system might be linked to issues like needing to go to the bathroom often, feeling an urgent need to go, or experiencing pain when you urinate, and it aims to find better ways to help people with these symptoms.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-10689024

Related topics

Quick answers

How many Lower Urinary Tract Symptoms clinical trials are recruiting right now?

17, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 26 countries. The most sites are in Egypt (6 trials), Denmark (3 trials), United States (3 trials), China (2 trials), Hong Kong (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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