Condition

Mental Disorders clinical trials and research

• 21Clinical trials
• 21NIH research projects
• 11Countries

Newest Mental Disorders clinical trials

All recruiting trials (21)

• Trauma-focused group therapy for adults with trauma symptoms in primary care

  A group-based trauma therapy delivered in primary care to see if it helps adults with trauma-related symptoms more than usual care.

  Recruiting University Ramon Llull · Barcelona, Barcelona · NCT07757334

• Does extra family income improve child mental health and brain biology in low-income families?

  This study tests whether three years of extra income for parents can improve their child’s mental health and neuroimmune function.

  Recruiting Northwestern University · Evanston, Illinois · NCT07641244

• Understanding and Targeting Self-Regulatory Control in Bulimia Nervosa

  In women with bulimia nervosa, this study tests whether real-time brain feedback during eating, paired with a 4-week text-message program, can help improve self-control and reduce symptoms.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT07581158

• Ear acupressure plus nicotine replacement to ease withdrawal in psychiatric inpatients

  This study will test whether adding ear acupressure (ear seeds) to standard nicotine replacement therapy helps psychiatric inpatients who must stop smoking reduce withdrawal symptoms, cravings, and anxiety.

  Recruiting TsaoTun Psychiatric Center, Department of Health, Taiwan · Nantou City · NCT07466875

• Psychosocial factors linked to outcomes in people with dual diagnosis in a hospital

  This study tests how psychosocial protective factors relate to clinical and functional outcomes in adults hospitalized with both a mental health disorder and substance use disorder.

  Recruiting Hospital Virgen del Puerto · Plasencia, Caceres · NCT07443033

• SMART treatment for youth with complex trauma

  This trial tests whether Sensory Motor Arousal Regulation Treatment (SMART) helps kids aged 7–17 with developmental trauma more than usual therapy.

  Recruiting at 4 sites Vestre Viken Hospital Trust · Asker, Akershus and 3 other locations · NCT07200713

• Virtual training for psychotherapists to improve patient mental health

  The study will test whether a virtual professional-development program helps psychotherapists in North America spot and fix problems in the therapist–patient relationship and improve adult patients' mental health.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT07087730

• Education program for quitting smoking

  This study is testing an education program to help people with mental health disorders who smoke to quit by providing support from nurses.

  Recruiting Erzurum Technical University · Erzurum, Erzurum · NCT06930547

• Detecting immune inflammation and brain changes in schizophrenia

  This study looks at how inflammation in the immune system might be linked to schizophrenia by comparing patients with the condition to healthy individuals over three months.

  Recruiting Central South University · Changsha, Hunan · NCT06673966

• Exploring brain structure and gene expression in mental disorders

  This study looks at how brain structure and genes relate to schizophrenia and other mental disorders in young people to better understand these conditions.

  Recruiting Second Xiangya Hospital of Central South University · Changsha, Hunan · NCT06580860

• Group treatment for self-stigma in people with mental disorders in Northeast Italy

  This study is testing a group therapy called Narrative Enhancement and Cognitive Therapy to see if it can help people with mental disorders in Northeast Italy feel better about themselves and reduce feelings of self-stigma.

  Recruiting Universita di Verona · Verona · NCT06567145

• Testing a new drug for treatment-resistant depression

  This study is testing a new drug called HNK to see if it can help people with treatment-resistant depression feel better when other medications haven't worked.

  Recruiting Phase 2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT06511908

• Improving chronic pain care with mindfulness and management visits

  This study is testing if combining mindfulness practices with personalized pain management visits can help people with chronic pain feel better and reduce their reliance on opioids.

  Recruiting at 3 sites Phase 3 University of Utah · La Jolla, California and 2 other locations · NCT06387290

• Investigating brain activity in children with overactive bladder and urinary incontinence

  This study is testing how brain activity differs in children with overactive bladder and urinary incontinence compared to healthy kids, to see if a new treatment can help improve their bladder control.

  Recruiting Aalborg University Hospital · Aalborg and 3 other locations · NCT05989646

• Understanding brain emotion processing in epilepsy patients

  This study is trying to understand how people with epilepsy process emotions in their brains to see if new treatments can help improve their emotional health.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT05854160

• Training mental health teams to improve patient recovery

  This study is testing a training program for mental health teams to see if it helps them support patients with mental disorders in their recovery better.

  Recruiting Hôpital le Vinatier · Lyon, Rhône · NCT05824234

• Improving PTSD treatment for veterans with serious mental illness

  This study is testing if a new therapy called Written Exposure Therapy can help veterans with PTSD and serious mental illness feel better, especially focusing on the experiences of Black, Indigenous, and other people of color.

  Recruiting VA Office of Research and Development · Baltimore, Maryland · NCT05674617

• A study on brain health and aging in Bordeaux.

  This study is trying to understand how different factors, like diet and health, affect brain aging and the risk of dementia in people aged 55 and older living in Bordeaux.

  Recruiting University Hospital, Bordeaux · Bordeaux, Bordeaux · NCT05322343

• Observing the use of ElectroConvulsive Therapy in France

  This study looks at how ElectroConvulsive Therapy is currently used to treat mental disorders in France to see if it can be improved for patients who need it.

  Recruiting at 15 sites Centre Hospitalier Henri Laborit · Angers and 29 other locations · NCT04477434

• Effects of Dexmedetomidine on cognitive recovery after cardiac surgery

  This study is testing if a medication called Dexmedetomidine can help people recover their thinking skills better after having heart surgery.

  Recruiting at 3 sites Phase 4 Sunnybrook Health Sciences Centre · Vancouver, British Columbia and 7 other locations · NCT04289142

• Home-use treatment for autism using Autowave technology

  This study is testing a home device that uses special wave technology to see if it can help improve the behavior and thinking skills of people with autism.

  Recruiting at 2 sites American Federation of Medical Synergetics · Louisville, Kentucky and 1 other locations · NCT03222375

NIH-funded research (21)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Personalized chatbot to help community health workers deliver interpersonal counseling in Mozambique

  A low-cost, chatbot-assisted program in Mozambique helps community health workers provide better interpersonal counseling for common mental disorders.

  NIH research University of Texas at Austin · Austin, United States · NIH-11535845

• Stepped mental health care within HIV services for Mozambican youth living with HIV

  A new approach tests how to integrate mental health care into HIV services for young people living with HIV in Mozambique using a stepped-care model.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11505799

• Reducing diagnostic differences to keep mental health patients safer

  A nationwide project at RAND aims to harmonize how clinicians diagnose mental disorders to prevent misdiagnoses and reduce harm from wrong medications.

  NIH research Rand Corporation · Santa Monica, United States · NIH-11424510

• Integrated peer-delivered mental health and HIV support for Mozambican youth with HIV

  A new program tests a stepped-care model where peers help deliver mental health and HIV care to Mozambican youth living with HIV.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11401816

• Causes and consequences of mental disorders: how parents shape their children

  A parent-focused study uses genetic and environmental data to understand how parental traits influence children’s mental health and behavior.

  NIH research University of Colorado · Boulder, UNITED STATES · NIH-11374811

• Early Life Adversity and Brain Development in Children at Risk for Mental Disorders

  This project follows children from birth to age 8 to understand how early social disadvantage and immune and gut health relate to brain development and later mental health risk.

  NIH research Washington University · Saint Louis, United States · NIH-11368504

• Personalized AI Chatbot to Improve Delivery of Interpersonal Counseling for Common Mental Disorders in Mozambique

  A custom AI chatbot is being tested to help non-specialist health workers deliver better, more affordable interpersonal counseling for depression, anxiety, and PTSD in Mozambique.

  NIH research University of Texas at Austin · Austin, United States · NIH-11307427

• Making mental health diagnoses more consistent to keep patients safer

  This project will make psychiatric diagnoses more consistent so people receiving mental health care are less likely to get the wrong medications.

  NIH research Rand Corporation · Santa Monica, United States · NIH-11193917

• Bringing proven mental health care into HIV clinics in Ukraine

  This project will adapt a short, practical mental health therapy plus a one-session adherence program to help adults with HIV in Ukraine feel better and stay on their HIV medicines.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11180185

• Understanding How Early Life Challenges Affect Children's Mental Health

  This project looks at how tough experiences early in life, like financial hardship, might change a child's brain and increase their chances of developing mental health challenges.

  NIH research Washington University · Saint Louis, United States · NIH-11131017

• Understanding how parents' genes and environment shape their children's mental health

  This project aims to understand how genetic and environmental factors passed down from parents influence mental health and other traits in children.

  NIH research University of Colorado · Boulder, UNITED STATES · NIH-11112351

• Exploring mental health treatment approaches in Ukraine's primary healthcare.

  This study is looking at how doctors and healthcare providers in Ukraine understand and use the best treatments for mental health issues like depression, anxiety, and substance use, with the goal of finding ways to make mental health care better and more accessible for everyone.

  NIH research Kyevo-Mogylyanska Akademiya, Natsionalny Universytet · Kyiv, Ukraine · NIH-11088273

• Improving the accuracy of mental disorder diagnoses to enhance patient safety

  This study is looking at how doctors and mental health providers can agree more on diagnosing mental health conditions so that patients get the right medications and better care.

  NIH research Rand Corporation · Santa Monica, United States · NIH-11016288

• Improving mental health treatment for people with HIV in Ukraine

  This study is looking to improve mental health support for people living with HIV in Ukraine by using a special program to help with feelings of depression, anxiety, and stress, so that they can stick to their HIV treatment better.

  NIH research Harvard School of Public Health · Boston, United States · NIH-10909344

• Using online therapy to help college students with mental health issues in Latin America

  This study is looking to help college students in Colombia and Mexico who are dealing with depression and anxiety by offering them online therapy, so they can get support right away while waiting for traditional services.

  NIH research National Institute of Psychiatry · Ciudad de Mexico, Mexico · NIH-10891384

• Understanding how synaptic dysfunction contributes to mental disorders

  This study is looking at how problems with brain connections might contribute to conditions like autism and schizophrenia, using special techniques to create brain cells from patients' own stem cells, with the hope of finding new ways to help improve mental health.

  NIH research University of Massachusetts Amherst · Hadley, United States · NIH-10767812

• Helping women displaced by war in Ukraine avoid mental health issues

  This study is looking at how to help women who have been displaced by the war in Ukraine to prevent mental health issues by using a supportive therapy that focuses on acceptance and mindfulness, with the goal of making them feel better and more flexible in their thinking.

  NIH research Boston Medical Center · Boston, United States · NIH-10730622

• Understanding mental health risks and protections for migrants in Mexico

  This study looks at the mental health struggles of migrants and asylum seekers in Mexico to understand what makes their mental health better or worse, and it aims to gather information over time through surveys and interviews to help improve support for them.

  NIH research Columbia University Health Sciences · New York, United States · NIH-10730324

• Investigating effective mental health treatments in Kenya

  This study is looking at how regular healthcare workers in Kenya can help people with depression and anxiety get the right treatments they need, making mental health care easier to access for everyone.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-10681458

• Improving mental health treatment for opioid addiction in Ukraine

  This study is looking to improve mental health care for people in Ukraine who are getting treatment for opioid addiction, like methadone or buprenorphine, by helping them get better support for depression and other mental health issues.

  NIH research Ukrainian Institute on Public Health Policy · Kyiv, UKRAINE · NIH-10415055

• Finding new drugs for mental disorders from traditional plants

  This study is exploring how traditional plants from Peru might help find new treatments for mental health issues like anxiety and depression by looking for helpful compounds in their extracts.

  NIH research Universidad Peruana Cayetano Heredia · Lima, Peru · NIH-10224360

Related topics

Quick answers

How many Mental Disorders clinical trials are recruiting right now?

21, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in United States (7 trials), France (3 trials), Spain (2 trials), China (2 trials), Canada (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 1, Phase 2: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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