Investigating how life stress affects bladder health and urinary symptoms
Official title: CARDIA-PLUS: A Life Course Investigation of Biopsychosocial Pathways to Bladder Health and Lower Urinary Tract Symptoms
Funded at University of Minnesota · NIH-10906163 · Data updated 2026-11-12
This study looks at how different life stresses can affect bladder health and urinary issues in both men and women, aiming to find ways to keep your bladder healthy and prevent problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | August 15, 2021 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $566,131 |
| NIH project number | 5R01DK125274-04 |
| Project ID | NIH-10906163 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults experiencing lower urinary tract symptoms or those interested in bladder health, particularly women and men from diverse socioeconomic backgrounds.
✕Less likely to help
Patients who do not experience any urinary symptoms or have no interest in bladder health may not benefit from this research.
What this research studies
This research explores how various psychosocial and socioeconomic stressors impact bladder health and lower urinary tract symptoms (LUTS) in both women and men throughout their lives. It examines four key pathways: affective, cognitive, behavioral, and physiological, using data from the long-term CARDIA study and the PLUS Research Consortium. By understanding these connections, the research aims to identify factors that promote bladder health and well-being, which can help in developing preventive strategies for LUTS.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing and managing bladder health issues, enhancing the quality of life for affected individuals.
How similar studies have gone: Previous research has shown success in understanding the impact of psychosocial factors on health outcomes, suggesting that this approach may yield valuable insights.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Brady, Sonya S — University of Minnesota
- Study coordinator: Brady, Sonya S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.