Ejaculation-Preserving Bipolar Prostate Enucleation for BPH

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective randomized trial compares an ejaculation-preserving modification of bipolar transurethral enucleation of the prostate (B-TUEP) to the standard B-TUEP in sexually active men with benign prostatic hyperplasia and lower urinary tract symptoms after failure of medical therapy. Participants are assigned 1:1 to either the ejaculation-preserving technique or the standard procedure, and outcomes include ejaculatory and erectile function, urinary symptom scores, urine flow metrics, residual urine, perioperative complications, and need for retreatment over follow-up. The ejaculation-preserving approach maintains paracollicular tissue and nearby structures to try to preserve ejaculation, while the control uses the conventional enucleation approach. Validated questionnaires and objective urinary parameters assess functional outcomes. The study aims to determine if the modified technique can achieve similar relief of symptoms with better preservation of sexual function.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Male patients with lower urinary tract symptoms secondary to benign prostatic obstruction after failed medical treatment for at least 3 months.
* Sexually active patients with a continuous relationship with the same partner.
* International Prostate Symptom Score of 8 or greater.
* Transrectal ultrasound-estimated prostate size between 40 and 100 cc.
* Eligible for bipolar transurethral enucleation of the prostate.
* Ability to complete the required sexual and urinary function questionnaires.
* Ability to provide written informed consent.

Exclusion Criteria:

* Preoperative sexual dysfunction.
* Preoperative ejaculatory dysfunction.
* Diagnosis or suspicion of prostate cancer.
* Neurological disorders affecting lower urinary tract or sexual function.
* Detrusor hypocontractility.
* Catheter-dependent patients.
* Patients with bladder stones.
* Inability or refusal to provide informed consent.

Where it's running

• Department of Urology- Beni-Suef University Hospitals
  Banī Suwayf, Beni Suweif Governorate, Egypt Recruiting

Study contacts

• Principal investigator: Hany F Badawy, MD — Faculty of medicine Beni-Suef University
• Study coordinator: Hany F Badawy, MD
• Email: HANYFATHY86@GMAIL.COM
• Phone: +201149525028

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.