Investigating the effects of low-dose vitamin D on kidney failure patients
Comparative Safety and Efficacy of Low-dose Vitamin D in Kidney Failure
['FUNDING_OTHER'] · UNIVERSITY OF WASHINGTON · NIH-11081703
This study is looking at how small amounts of vitamin D might help people with kidney failure who are on dialysis, especially in keeping their hearts healthy, and it aims to find the safest and most effective way to use vitamin D for managing bone and mineral issues in these patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WASHINGTON (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-11081703 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how low doses of vitamin D can impact patients with kidney failure, particularly those undergoing dialysis. It examines the relationship between vitamin D receptor agonists and cardiovascular disease, which is a significant risk for these patients. The study aims to evaluate the long-term safety and efficacy of vitamin D treatments, addressing potential risks associated with high doses. By analyzing patient outcomes, the research seeks to determine the best approach to manage mineral and bone disorders in kidney failure.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with chronic kidney disease who are on dialysis and experiencing mineral and bone disorders.
Not a fit: Patients with kidney failure who are not on dialysis or those without mineral and bone disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective vitamin D treatment protocols for patients with kidney failure, potentially reducing cardiovascular risks.
How similar studies have performed: Previous research has indicated that vitamin D receptor agonists can improve cardiovascular outcomes in kidney failure patients, suggesting a promising avenue for this investigation.
Where this research is happening
SEATTLE, UNITED STATES
- UNIVERSITY OF WASHINGTON — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HSU, SIMON — UNIVERSITY OF WASHINGTON
- Study coordinator: HSU, SIMON
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.