Investigating the effects of low-dose vitamin D on kidney failure patients
Official title: Comparative Safety and Efficacy of Low-dose Vitamin D in Kidney Failure
Funded at University of Washington · NIH-11081703 · Data updated 2026-11-12
This study is looking at how small amounts of vitamin D might help people with kidney failure who are on dialysis, especially in keeping their hearts healthy, and it aims to find the safest and most effective way to use vitamin D for managing bone and mineral issues in these patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | August 1, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $186,516 |
| NIH project number | 5K23DK136930-03 |
| Project ID | NIH-11081703 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with chronic kidney disease who are on dialysis and experiencing mineral and bone disorders.
✕Less likely to help
Patients with kidney failure who are not on dialysis or those without mineral and bone disorders may not benefit from this research.
What this research studies
This research focuses on understanding how low doses of vitamin D can impact patients with kidney failure, particularly those undergoing dialysis. It examines the relationship between vitamin D receptor agonists and cardiovascular disease, which is a significant risk for these patients. The study aims to evaluate the long-term safety and efficacy of vitamin D treatments, addressing potential risks associated with high doses. By analyzing patient outcomes, the research seeks to determine the best approach to manage mineral and bone disorders in kidney failure.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective vitamin D treatment protocols for patients with kidney failure, potentially reducing cardiovascular risks.
How similar studies have gone: Previous research has indicated that vitamin D receptor agonists can improve cardiovascular outcomes in kidney failure patients, suggesting a promising avenue for this investigation.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Hsu, Simon — University of Washington
- Study coordinator: Hsu, Simon
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.