High-protein egg white pudding for people on dialysis
Official title: A High Protein Egg White Pudding for People With Kidney Failure (HiPE KF)
Run by Seven Oaks Hospital Chronic Disease Innovation Centre · NCT06343727 · Data updated 2026-11-12
This trial will try whether giving an egg white protein pudding to adults on in-center hemodialysis with low albumin helps their nutrition compared with a standard supplement (Ensure Plus).
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 54 (estimated) |
| Sponsor | Seven Oaks Hospital Chronic Disease Innovation Centre Research network |
| Drugs / interventions | chemotherapy |
| Locations | 2 sites (Winnipeg, Manitoba and 1 other locations) |
| Status | Recruiting |
| Started | July 25, 2025 |
| Main results expected | August 11, 2026 |
| Study ends | October 1, 2026 |
| Registry record updated | April 22, 2026 |
| Trial ID | NCT06343727 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (≥18) on chronic in-center hemodialysis for more than three months with serum albumin below 35 g/L who can consume the product and give informed consent.
✕Probably not a fit
People with egg allergy, recent transplant history, active cancer, pregnancy, current chemotherapy, inability to eat the product, or normal serum albumin (≥35 g/L) are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study compares an egg white protein pudding to a standard oral nutritional supplement (Ensure Plus) in adults on chronic in-center hemodialysis who have low serum albumin. Participants receive the assigned supplement at the end of their dialysis sessions three times per week for 12 weeks. The trial will test feasibility of delivering the pudding and whether it raises serum albumin similarly to Ensure Plus, with secondary measures including frailty tests, dietary intake, and blood analytes. The study is run at two Winnipeg hospitals and enrolls adults who can consent, have been on dialysis for over three months, and have serum albumin under 35 g/L.
Why it matters
Potential benefit: If successful, the pudding could provide an affordable, egg-based protein option that improves serum albumin and physical frailty in dialysis patients.
How similar studies have gone: Oral protein supplements such as Ensure have shown modest benefits in dialysis populations in prior studies, but the specific egg white pudding formulation is a novel approach without large prior trials.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participant is willing and able to give informed consent for participation in the trial * Male or female aged ≥18 years with CKD * On chronic in-center hemodialysis for \> 3 months * Serum albumin \<35 g/L * No expected change in dialysis modality or relocation outside of Winnipeg during the intervention period (12 weeks) Exclusion Criteria: * Allergy to eggs * History of renal transplant * Serum albumin ≥ 35 g/L * Bowel diseases * Cancer * Pregnancy * Receiving chemotherapy treatment * Inability to consume treatment product * Allergy to study treatment ingredients * Planning on starting an exercise program during the duration of the trial * Inability to obtain written informed consent
Where it's running
-
Seven Oaks General Hospital
Winnipeg, Manitoba, Canada Recruiting -
Health Science Centre
Winnipeg, Manitoba, Canada Recruiting
Study contacts
- Study coordinator: Navdeep Tangri, MD, PhD
- Email: ntangri@sogh.mb.ca
- Phone: 2046313834
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.