Condition

Kawasaki Disease clinical trials and research

• 10Clinical trials
• 11NIH research projects
• 15Countries

Newest Kawasaki Disease clinical trials

All recruiting trials (10)

• Atorvastatin in Chinese children with Kawasaki disease and coronary artery abnormalities

  This phase 3 study tests whether atorvastatin is safe and helpful for children with Kawasaki disease who have coronary artery abnormalities.

  Recruiting Phase 3 Children's Hospital of Fudan University · Shanghai · NCT07530640

• Kawasaki MATCH decision support for suspected Kawasaki disease

  This study will test a machine-learning tool called Kawasaki MATCH to help providers decide if febrile children might have Kawasaki disease.

  Recruiting University of California, San Diego · San Diego, California · NCT07291245

• Cardiovascular health in children and young adults with chronic conditions

  This project will see if children and young adults (ages 6-25) with chronic health conditions show early signs of aging in large and small blood vessels using noninvasive imaging and clinical tests.

  Recruiting Semmelweis University · Budapest and 2 other locations · NCT07086989

• Analyzing Rivaroxaban in Chinese Children with Kawasaki Disease

  This study is testing how well the blood thinner rivaroxaban works in children with Kawasaki disease who have serious heart problems.

  Recruiting Children's Hospital of Fudan University · Shanghai, Shanghai Municipality · NCT06993636

• Optimizing Rivaroxaban Dosing for Children with Giant Coronary Aneurysms After Kawasaki Disease

  This study is testing a new way to dose a blood thinner called rivaroxaban for Chinese children with giant coronary aneurysms after Kawasaki disease to see if it helps prevent heart problems.

  Recruiting Phase 4 Children's Hospital of Fudan University · Shanghai, Shanghai Municipality · NCT06978439

• Observing Kawasaki disease in European and North Indian children

  This study looks at children with Kawasaki disease to see if certain scoring systems can help identify those who don't respond to standard treatment, focusing on kids from Europe and North India.

  Recruiting at 17 sites Meyer Children's Hospital IRCCS · Rio de Janeiro and 26 other locations · NCT06305611

• Rivaroxaban for children over 2 with giant coronary artery aneurysms after Kawasaki disease

  This trial will test whether rivaroxaban given with an antiplatelet medicine is a safe and practical alternative to warfarin for preventing clots in children aged 2 and older with giant coronary artery aneurysms after Kawasaki disease.

  Recruiting Phase 4 Children's Hospital of Fudan University · Shanghai, Shanghai Municipality · NCT05643651

• Comparing Anakinra and IVIG for Kawasaki Disease Treatment

  This study is testing if Anakinra can help children with Kawasaki Disease who didn't get better with the usual IVIG treatment by reducing fever and improving their health within two days.

  Recruiting Phase 3 Assistance Publique - Hôpitaux de Paris · Le Kremlin-Bicêtre, Val De Marne · NCT04656184

• Understanding how drugs work in children

  This study is trying to find the best and safest doses of certain medications for children and young adults under 21 who are being treated for conditions like COVID-19 and pulmonary arterial hypertension.

  Recruiting at 5 sites Duke University · Phoenix, Arizona and 51 other locations · NCT04278404

• Registry for patients with rare diseases

  This study is creating a central registry for people with rare diseases to help connect them with researchers and improve treatments.

  Recruiting Sanford Health · Sioux Falls, South Dakota · NCT01793168

NIH-funded research (11)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Gut bacteria and permeability linked to Kawasaki disease in kids

  A pediatric-focused study exploring how the gut microbiome and intestinal barrier may influence Kawasaki disease and its inflammation.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11414974

• Cell-free RNA test to quickly diagnose Kawasaki disease in children

  A new blood test using cell-free RNA will help doctors diagnose Kawasaki disease in kids faster, leading to earlier treatment.

  NIH research Romix Biosciences INC. · Waltham, United States · NIH-11405945

• Role of sex in immune-stromal cell interactions driving Kawasaki disease vasculitis

  This project looks at why Kawasaki disease causes heart problems in kids and how sex differences affect the immune cell interactions that lead to artery inflammation.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11394203

• Cell-free RNA signature to diagnose Kawasaki disease and guide personalized treatment in kids

  A new blood test using tiny fragments of RNA found in the blood is being studied to help diagnose Kawasaki disease in children and tailor treatments to prevent heart complications.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11294040

• Sex differences in immune–vessel cell interactions in Kawasaki disease

  This project looks at how being male or female changes immune and blood-vessel cell behavior that leads to coronary artery damage in people with Kawasaki disease.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11189694

• Gut bacteria and 'leaky' gut in Kawasaki disease

  This research looks at whether changes in gut bacteria and a 'leaky' gut make Kawasaki disease worse in young children.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11133777

• Investigating how sex affects immune interactions in Kawasaki disease

  This study is looking at how Kawasaki disease affects kids and how the immune system interacts with blood vessels differently in boys and girls, with the goal of finding better treatments for those who don’t respond to regular therapies.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-10990212

• Finding specific targets related to Kawasaki Disease

  This study is looking at Kawasaki Disease in kids to find out what triggers the immune response, which could help doctors diagnose it earlier and prevent serious heart problems.

  NIH research Lurie Children's Hospital of Chicago · Chicago, United States · NIH-10894818

• Investigating how Sirt-1 affects inflammation in Kawasaki Disease

  This study is looking at Kawasaki Disease in kids and how a specific pathway in the body might help reduce inflammation in their blood vessels, with hopes of finding better treatments to keep their hearts healthy.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-10890070

• Identifying and managing a serious inflammatory syndrome in children linked to COVID-19.

  This study is looking at a condition called Multisystem Inflammatory Syndrome in Children (MIS-C), which has come up during the COVID-19 pandemic, and aims to create helpful tools for doctors to better diagnose and treat kids with MIS-C or Kawasaki disease by using data from past cases.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-10847802

• Using data science to improve diagnosis and management of MIS-C in children

  This study is looking at a condition called multisystem inflammatory syndrome in children (MIS-C), which has come up during the COVID-19 pandemic, and it aims to create helpful tools for doctors to better diagnose and treat kids who show signs of MIS-C or Kawasaki disease.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-10733695

Related topics

Quick answers

How many Kawasaki Disease clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 15 countries. The most sites are in China (4 trials), United States (3 trials), France (2 trials), Canada (1 trial), Hungary (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Phase 4: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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