Condition

Atypical Hemolytic Uremic Syndrome clinical trials and research

• 9Clinical trials
• 22Countries

Newest Atypical Hemolytic Uremic Syndrome clinical trials

All recruiting trials (9)

• Ravulizumab Outcomes in Polish Patients with aHUS

  This observational study in Poland follows patients with atypical hemolytic uremic syndrome who are treated with ravulizumab to see how they do over time in real-world clinical care.

  Recruiting at 5 sites AstraZeneca · Gdansk and 9 other locations · NCT07399730

• Ravulizumab for people with clinical aHUS

  This study will test whether ravulizumab raises platelet counts in people diagnosed with clinical atypical hemolytic uremic syndrome (aHUS), including those with certain infections (excluding pneumococcal and STEC), pregnancy/postpartum, recent kidney transplant, malignant hypertension, or autoimmune conditions.

  Recruiting at 3 sites Phase 4 Alexion Pharmaceuticals, Inc. · Bunkyō City and 11 other locations · NCT07308574

• National Registry for Rare Kidney Diseases

  This study is collecting health information from people with rare kidney diseases to help improve treatments and create better care guidelines.

  Recruiting UK Kidney Association · Bristol, South West · NCT06065852

• Using RNA sequencing to diagnose rare genetic diseases

  This study is testing if a new RNA sequencing method can help find the genetic causes of rare diseases in people who haven't been diagnosed after other tests.

  Recruiting Mario Negri Institute for Pharmacological Research · Ranica, BG · NCT05996731

• Switching from anti-C5 antibody treatment to iptacopan for aHUS patients

  This study is testing if switching to a new treatment called iptacopan can help people with atypical hemolytic uremic syndrome (aHUS) feel better after using a different medication.

  Recruiting at 26 sites Phase 3 Novartis · Nanjing, Jiangsu and 30 other locations · NCT05935215

• Understanding rare gene mutations in atypical hemolytic uremic syndrome for personalized therapy

  This study is testing how rare gene mutations in people with atypical hemolytic uremic syndrome can help doctors create personalized treatments to improve their health.

  Recruiting Mario Negri Institute for Pharmacological Research · Ranica, BG · NCT05805202

• Long-term evaluation of iptacopan for patients with atypical hemolytic uremic syndrome

  This study is testing how well the medication iptacopan works and how safe it is for people with atypical hemolytic uremic syndrome over a longer period of time.

  Recruiting at 7 sites Phase 3 Novartis · São Paulo, São Paulo and 8 other locations · NCT05795140

• Registry for patients with rare diseases

  This study is creating a central registry for people with rare diseases to help connect them with researchers and improve treatments.

  Recruiting Sanford Health · Sioux Falls, South Dakota · NCT01793168

• Registry for patients with Atypical Hemolytic-Uremic Syndrome

  This study is collecting information from people with Atypical Hemolytic-Uremic Syndrome to see how the disease progresses in those treated with eculizumab or ravulizumab and those who aren't treated at all.

  Recruiting at 118 sites Alexion Pharmaceuticals, Inc. · Aurora, Colorado and 140 other locations · NCT01522183

Related topics

Quick answers

How many Atypical Hemolytic Uremic Syndrome clinical trials are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 22 countries. The most sites are in Italy (4 trials), Japan (3 trials), Turkey (Türkiye) (3 trials), United Kingdom (3 trials), France (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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