Condition
Hearing Loss clinical trials and research
As of November 12, 2026, Find a Trial lists 51 Hearing Loss clinical trials that are recruiting, at sites in 15 countries (most in United States (29), France (5), United Kingdom (4)). By phase: Phase 2 (2), Phase 1 (1), Phase 1/2 (1). The most active sponsors are National Institutes of Health Clinical Center (CC) (4), University of Arkansas (2), University of Pretoria (2). There are also 155 NIH-funded research projects on Hearing Loss, with $86.2 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 51Clinical trials
- 155NIH research projects
- 15Countries
Newest Hearing Loss clinical trials
All recruiting trials (51)
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WhatsApp AI support vs paper support for first-time hearing aid users
This study tests whether a WhatsApp-based AI support program helps adults with new hearing aids in LMIC communities use and feel confident about their devices better than a paper pamphlet.
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Hearing and Brain Development in Children and Teens
This observational study tests how hearing care paths (like hearing aids, cochlear implants, brainstem implants, gene therapy, or no intervention) relate to hearing, speech, language, and brain development in kids and teens, with a normal-hearing group for comparison.
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Web-based auditory training with easy versus hard task settings to improve speech and listening
This project will test whether easy or hard versions of a web-based auditory training program help adults with hearing loss improve speech understanding and everyday listening.
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Long-term hearing and speech outcomes after cochlear implants
This project will see if cochlear implants improve hearing, speech understanding, and quality of life in Mandarin-speaking patients of all ages before and after surgery.
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Clemastine plus engineered sound to improve hearing in noisy environments for age-related central auditory processing disorder
This trial will test whether taking clemastine while listening to engineered sounds helps people aged 45–65 with age-related central auditory processing disorder hear better in noisy places.
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Add Pedmark to cisplatin chemotherapy to prevent hearing loss in men with stage II–III metastatic testicular germ cell tumors
We will test whether adding Pedmark to cisplatin chemotherapy reduces hearing damage in men with stage II–III metastatic testicular germ cell tumors.
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Noninvasive ear stimulation to improve hearing speech in noisy places
This will test whether gentle electrical stimulation of the ear can help people with traumatic brain injury hear speech more clearly in noisy environments.
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Adapting the Mainzer Audiometric Test for Children (MATCH) into another language
This project tries to adapt and standardize a children's speech hearing test (MATCH) into another language so clinicians can measure how well 3–6-year-olds with and without hearing loss understand speech.
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Text-message support to help new NHS hearing aid users keep using their hearing aids
This trial will test whether sending standardised NHS text messages to adults starting hearing aids helps them use their devices more regularly.
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Placing the cochlear implant ground electrode near the post-auricular vagus nerve
This will test whether placing the cochlear implant's ground electrode near the post-auricular vagus nerve works as well as placing it under the temporalis muscle for people getting a Cochlear Americas implant.
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Community-based hearing aid fittings by community healthcare workers using smartphone-guided and pre-set devices in low- and middle-income communities.
This project will test whether community healthcare workers using smartphone-guided and pre-set hearing aid fittings help adults with mild-to-severe hearing loss in low- and middle-income communities hear better than minimal amplification.
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ENACT: Integrated hearing and cognitive training for people with mild cognitive impairment
This program tests whether adding online auditory training to cognitive training helps people with mild cognitive impairment who also have hearing loss.
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Evaluating outcomes of Ponto procedures done outside the main operating room
This study looks at how well Ponto implant surgeries done outside the main operating room work for patients and whether they have any complications.
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Hearing care to reduce neuropsychiatric symptoms in people with Alzheimer's and related dementias
This trial will try a tailored, community-delivered hearing care program using HEARS devices to see if it improves communication, reduces neuropsychiatric symptoms, and eases caregiver distress in English-speaking older adults with Alzheimer's disease or related dementias who have untreated hearing loss.
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Cisplatin-related (Ear) Hearing Loss and Balance Issues in Head and Neck Cancer Patients
This observational study tests whether hearing loss, tinnitus, and balance problems occur in head and neck cancer patients treated with cisplatin chemoradiotherapy compared with those receiving only radiotherapy, including optional genetic tests for susceptibility.
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Impact of vestibular function on daily activities of deaf infants
This study tests how vestibular problems affect daily tasks in deaf children aged 0–2 years.
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Sentio system safety and performance for adolescents 12–17
This project will test how safe and well the Sentio hearing system works for adolescents aged 12–17 with conductive or mixed hearing loss, single-sided deafness, or who need an AC CROS device.
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Improving hearing with AI noise reduction in hearing aids
This study is testing a new AI noise reduction feature in Phonak hearing aids to see if it helps people with hearing loss hear and understand speech better.
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Comparing over-the-counter and prescription hearing aids for better hearing access
This study tests whether over-the-counter hearing aids work as well as prescription ones for people with mild to moderate hearing loss and looks at how they affect hearing experiences and costs.
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Understanding listening effort in cochlear implant users
This study tests how much effort people with cochlear implants need to understand speech compared to those with normal hearing, using speech tests and measuring pupil size to see how hard they are working to listen.
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Investigating auditory nerve activity in patients with hearing loss
This study is testing how well the nerves that help us hear work in people with hearing loss, especially in noisy situations, to better understand their hearing challenges.
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Understanding how context affects speech perception in people with normal and impaired hearing
This study tests how background sounds affect the ability of people with normal and impaired hearing to understand speech.
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Investigation of Automatic Technologies for Children with Hearing Loss
This study tests a new technology to see if it helps children with hearing loss understand speech better in noisy places like classrooms and playgrounds.
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Using mild cooling during cochlear implant surgery to preserve hearing
This study tests if using mild cooling during cochlear implant surgery can help people with severe hearing loss keep some of their natural hearing.
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SPI-1005 to help preserve hearing during cochlear implant surgery
This trial will test whether taking SPI-1005 (ebselen) around the time of surgery is safe and helps preserve hearing and reduce tinnitus or vertigo in adults receiving a MED‑EL long‑array cochlear implant.
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Collection of biological samples for research on head and neck disorders
This study is collecting biological samples from people with head and neck disorders to see how these conditions develop and find better ways to diagnose and treat them.
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Comparing speech perception in cochlear implant patients and those receiving gene therapy for hearing loss
This study is trying to see how well people with cochlear implants hear and understand speech compared to those who have received gene therapy for hearing loss.
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Investigating the impact of hearing aids on cognitive decline in older adults
This study is testing if using hearing aids can help older adults with early hearing loss and mild memory problems think better and stay socially active compared to those who only get health education.
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Using OTC hearing aids to improve communication in older adults with mild cognitive impairment
This study is testing if Over-the-Counter hearing aids can help older adults with mild cognitive impairment communicate better compared to just using communication tips.
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Improving speech clarity for adults with cochlear implants
This study is testing new ways to improve how well adults with cochlear implants can understand speech in noisy environments.
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Hearing screening for preschool children
This study is testing two different ways to check hearing in preschool children to see which method works better for finding hearing loss early and helping kids who might struggle with speech and language.
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Combining electric and acoustic hearing for better outcomes in children and adults
This study tests if combining electric and acoustic hearing helps children and adults with cochlear implants understand speech better and hear sounds around them more clearly.
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BEARS directional-listening training to improve hearing in older children and teens with two cochlear implants
This trial tests whether 3 months of the BEARS virtual-reality directional listening training, added to usual care, helps 8–16 year olds with two cochlear implants hear better in noisy places, reduce listening effort, and improve vocabulary and quality of life.
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Cochlear implants for young children with single-sided deafness
This study is testing if cochlear implants can help young children with single-sided deafness hear better and develop language skills as they grow.
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Collecting data and samples for research on hearing and communication disorders
This study is collecting health information and samples from people aged 2 and up with hearing and communication disorders to help with future research on these issues.
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Observational registry for MED-EL hearing devices
This study collects information from children and adults using MED-EL hearing devices to see how well they work and how they improve people's lives.
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Screening and telemedicine for childhood hearing loss in rural Alaska
This study is testing a telemedicine program to see if it can help improve follow-up care for children with hearing loss in rural Alaska after they are screened at school.
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Hearing diagnostics using Sound Ear Check in young children
This study is testing a new tablet-based hearing test called Sound Ear Check to see if it can help find hearing problems in healthy children aged 3 to 10 who are getting ear tubes.
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Screening and telemedicine referral for childhood hearing loss in rural Kentucky
This study is testing a new way to check for hearing problems in kids at rural Kentucky schools using mobile health tools and telemedicine to make sure they get the care they need.
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Using smart hearing aids to assess and reduce fall risk while improving speech clarity
This study is testing smart hearing aids that can help older adults not only hear better but also see if they can reduce the risk of falls by tracking their movements and activities.
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Improving hearing performance for cochlear implant users
This study is testing new ways to help people with cochlear implants, especially those with some hearing in their other ear, improve their ability to understand speech.
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Improving hearing in noisy environments for hearing aid users
This study is testing different ways to help hearing aid users understand speech better in noisy places and see how different hearing aid styles affect their ability to hear sounds around them.
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Measuring brain responses to visual stimuli in people with hearing loss
This study is testing how the brain responds to visual images in people with hearing loss to see if it can help improve treatments for their condition.
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Improving hearing for Veterans in emergency departments
This study is testing whether personal amplifiers can help Veterans with hearing difficulties understand discharge instructions better in emergency departments and reduce their chances of going back to the hospital.
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Using atorvastatin to prevent hearing loss in head and neck cancer patients receiving cisplatin
This study is testing if atorvastatin can help prevent hearing loss in adults with head and neck cancer who are getting chemotherapy with cisplatin.
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Improving music and speech perception for cochlear implant users
This study is testing a new way to help cochlear implant users hear music and speech better by improving how they perceive sound details that are usually missed.
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Evaluating hearing aid effectiveness in children using brain imaging
This study is testing how well hearing aids work for young children with hearing loss by looking at their brain activity when they hear speech.
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Understanding the genetics of hereditary hearing loss
This study is trying to find out more about the genetics of a type of hearing loss that runs in families by looking at people with the condition and their relatives to help guide future treatments.
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Effects of Radiotherapy and Chemotherapy on Hearing in Head and Neck Cancer Patients
This study is trying to see how treatments for head and neck cancer, like radiotherapy and chemotherapy, affect hearing in patients and which parts of the ear are most at risk of damage.
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Using eABR to improve hearing outcomes after vestibular schwannoma surgery
This study is testing if measuring brain responses during vestibular schwannoma surgery can help predict how well patients will hear after getting cochlear implants.
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Cochlear implantation after gamma knife radiosurgery for vestibular schwannoma
This study is testing if cochlear implants can help people who have hearing loss after treatment for vestibular schwannoma with gamma knife radiosurgery.
NIH-funded research (newest 40 of 155)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Noise-related hearing loss and its link to Alzheimer's progression
Researchers are looking at whether hearing damage from loud noise speeds memory loss and dementia in people at risk for Alzheimer's.
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Audiological rehabilitation for children with unilateral hearing loss
A research project aims to help children who hear with one ear by testing ways to improve their hearing and communication through targeted audiology interventions.
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Choosing the right hearing device for kids with moderate-to-severe hearing loss
This grant explores which hearing device—hearing aids or cochlear implants—works best for children aged 0-11 with moderate-to-severe hearing loss.
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Noise-related hearing loss and brain-to-ear feedback in hearing protection
A small, patient-friendly study will look at how loud noise changes the brain’s control over hearing and whether this affects conditions like tinnitus or sensitivity to sound.
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How loud noise can change the brain's sound decisions
This project looks at how loud noise-related hearing loss may affect how people process sounds and make quick decisions about what they hear.
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Understanding how tactile language and wearable tech can help DeafBlind children learn and use language
A study at Gallaudet University tests a new tactile language and wearable haptic devices to help DeafBlind children build early language and everyday life skills.
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Understanding why age-related hearing loss and tinnitus happen in diverse groups
A study aims to find genetic reasons behind age-related hearing loss and tinnitus in African ancestry and Latino populations.
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Macrophages and hearing loss from cisplatin
This study looks at how immune cells in the ear called macrophages affect and may protect against hearing loss caused by the cancer drug cisplatin.
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Understanding residual hearing after unilateral hearing loss
This NIH grant explores how the remaining hearing in one ear is affected and what this means for balance and brain processing in adults with unilateral hearing loss.
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Peptide-guided delivery to the inner ear to prevent hearing loss
A study exploring a new peptide-based method to deliver treatments directly into the cochlea to prevent or slow hearing loss in patients with cochlear conditions.
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Understanding why phantom sounds and intolerance to sounds happen after hearing loss
This grant investigates why some adults with hearing loss experience tinnitus, hyperacusis, and trouble ignoring background noise, and how brain changes relate to these symptoms.
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Biomarkers linked to cochlear nerve damage in adults with sensorineural hearing loss
A project to find biological markers of cochlear nerve damage and see how they relate to hearing problems like difficulty hearing in noise and tinnitus in adults with hearing loss.
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Cochlear nerve connections and hearing loss in human temporal bones
A large, patient-facing research effort analyzes how nerve connections in the inner ear deteriorate in people with sensorineural hearing loss by studying post-mortem human temporal bones.
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Cochlear nerve disease and how it affects hearing in models of hearing loss
This grant studies how damage to the nerves of the ear happens and how it affects hearing in noisy places, using animal models to inform future human therapies.
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Hearing loss as a window into how language develops from infancy to school age
A study using hearing loss as a natural guide to understand why some children develop language skills while others don’t, with a focus on kids from infancy to school entry.
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Ear health and memory: can hearing aids help prevent cognitive decline in adults at risk for Alzheimer's
A focused study will test whether using hearing aids can help 55-75 year olds with early hearing loss keep their thinking sharper and reduce risk for Alzheimer’s-related changes.
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Smartphone middle‑ear tester to spot preventable childhood hearing problems
This project builds a low-cost smartphone-based middle‑ear tester with smart software to find treatable hearing problems in children in low- and middle-income countries.
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Enhanced delivery of hearing-restore therapeutics to the inner ear using nanovesicles in a pig model
Aims to test a safe, non-surgical way to deliver regenerative therapies into the inner ear of pigs using tiny vesicles to help prevent or treat hearing loss.
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Understanding why hearing loss affects women differently
This project looks at why hearing loss happens more in women and how menopause and immune factors might play a role, with the goal of better tools to identify and treat it.
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Hearing loss and lung health in World Trade Center responders
This grant looks at how exposure to loud noise and dust from the World Trade Center disaster may be linked to hearing loss and lung problems in FDNY responders over time.
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AAV-based gene editing to treat inherited hearing loss (DFNA41 and DFNA2)
A gene-editing therapy delivered by AAV aims to treat certain inherited forms of hearing loss in adults and children.
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Understanding how Zfp719 mutations cause adult hearing loss
Researchers are studying why changes in the Zfp719 gene lead to adult-onset hearing loss and what that could mean for people who start losing hearing later in life.
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Gene and Variant Curation Panels for Hearing Loss
A team is building and refining a global resource to accurately connect hearing loss genes and genetic variants with their clinical impact to improve diagnosis and care.
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A drug to protect hearing during antibiotic treatment
A company-sponsored project is testing a drug to help prevent hearing loss in adults who must take aminoglycoside antibiotics.
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Neural dynamics of sensory processing in children with hearing loss
This study explores how the brains of children with mild-to-severe hearing loss process sounds and other sensations, aiming to understand why listening and learning can be harder for them.
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Hearing care for older adults with dementia to ease neuropsychiatric symptoms
A Johns Hopkins study tests whether using new hearing care tools can reduce behavioral and mood symptoms in people 65 and older with Alzheimer’s or related dementias.
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Cochlear implants and hearing aids in older adults with hearing loss to understand links to memory and thinking
This study follows adults 65+ with age-related hearing loss to see how real-world use of cochlear implants or hearing aids relates to thinking skills and progression toward dementia.
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Multisensory decision-making with hearing loss in adults
A study in adults with and without hearing loss will look at how seeing lips and hearing sounds together influence decision-making, using animal models and brain measurements to understand the brain mechanisms involved.
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Genes behind age-related hearing loss
Researchers are looking at a specific genetic change to learn how it leads to hearing loss in older adults.
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Better ways to find what causes hearing loss
This project will create improved tools that combine hearing test patterns and people’s reports of their hearing to better understand hearing loss in adults.
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Targeted mild cooling to prevent hearing loss
This project develops a non-invasive, targeted mild cooling approach to help adults at risk of hearing loss from loud noise or certain medical treatments.
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Auditory nerve and brain pathways in noise-related hearing loss
A study to understand how loud noises damage the auditory nerve and central brain pathways, with the goal of informing better ways to prevent or treat noise-related hearing loss.
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How middle-ear fluid affects children's hearing and development
The team will compare children with middle-ear fluid who have little or no hearing loss to those with larger hearing losses to find which kids need treatment to protect speech, language, and listening skills.
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AI-driven genetic discovery for age-related hearing loss
A Stanford-led project uses artificial intelligence to find genetic factors that contribute to age-related hearing loss and to understand how they cause it.
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Cx26 Gap Junctions and Early Deafness: How Connexin 26 Deficiency Shapes Cochlear Development
Researchers are studying how lack of Connexin 26 affects the developing ear and leads to congenital or early hearing loss in children.
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Understanding how hearing loss contributes to falls in older adults
A Duke University study looks at why people with hearing loss may fall more, with the aim of guiding better ways to reduce falls.
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Understanding how Ménière’s disease progresses using an inner-ear model
This grant studies how hearing loss from Ménière’s disease develops in an animal model to uncover the biology of the inner ear.
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Sensorineural hearing loss and how it affects understanding speech
This project explores why people with similar hearing loss have different abilities to understand speech, especially in noisy places, and aims to uncover the brain and ear mechanisms behind these differences.
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Plasticity in the brain’s hearing network after hearing loss
This grant studies how the brain’s hearing centers change after loud noise or hearing loss, focusing on specific cells and protective structures to understand conditions like hyperacusis.
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Understanding why some people with hearing loss can’t understand speech in noise
This grant studies why some people with hearing loss can’t understand speech in noisy environments, even when they can hear it, to identify new ways to help them hear and understand better.
Related topics
Quick answers
How many Hearing Loss clinical trials are recruiting right now?
51, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 15 countries. The most sites are in United States (29 trials), France (5 trials), United Kingdom (4 trials), China (3 trials), Germany (2 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 2, Phase 1: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.