NIH-funded research R01 grant

How middle-ear fluid affects children's hearing and development

Official title: Hearing Loss, Prognosis, and Long-Term Impact of Otitis Media with Effusion in Children

Funded at Father Flanagan's Boys' Home · NIH-11342182 · Data updated 2026-11-12

The team will compare children with middle-ear fluid who have little or no hearing loss to those with larger hearing losses to find which kids need treatment to protect speech, language, and listening skills.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionFather Flanagan's Boys' Home
NIH-funded
Lab location1 site (Boys Town, United States)
Project startMay 4, 2026
Project endApril 30, 2030
Funding year2026
Award (this year)$707,126
NIH project number1R01DC023582-01
Project IDNIH-11342182 on NIH RePORTER

Who could benefit from this research

Could help

Children from infancy through about 11 years old who have middle-ear fluid (otitis media with effusion), especially those with persistent fluid or measurable hearing loss, would be good candidates.

Less likely to help

Children without middle-ear fluid, or those whose fluid causes no measurable or only very brief hearing loss, are unlikely to benefit directly from this work.

What this research studies

If your child joins, clinicians will measure their hearing with standard audiology tests and document how long middle-ear fluid (OME) lasts. They will track children over months to years to see how the degree and whether one or both ears are affected relate to later speech, language, and auditory processing. The researchers will look at the total amount of hearing loss over time (cumulative auditory deprivation) rather than just whether fluid was present. The goal is to identify which patterns of hearing loss put children at risk so care can be focused on those who need it most.

Why it matters

Potential benefit: Could help doctors target ear tube surgery and other care to the children most likely to develop speech, language, or learning problems.

How similar studies have gone: Previous studies have shown mixed results about long-term effects of middle-ear fluid, and this project is relatively novel in focusing on the cumulative amount and symmetry of hearing loss as the key risk factor.

Where this research is happening

  • Father Flanagan's Boys' Home
    Boys Town, United States
    Active

Researchers

  • Principal investigator: Merchant, Gabrielle Ryan — Father Flanagan's Boys' Home
  • Study coordinator: Merchant, Gabrielle Ryan

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.