AI-driven genetic discovery for age-related hearing loss
Official title: AI-based genetic discovery for hearing loss
Funded at Stanford University · NIH-11337542 · Data updated 2026-11-12
A Stanford-led project uses artificial intelligence to find genetic factors that contribute to age-related hearing loss and to understand how they cause it.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | June 16, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $607,953 |
| NIH project number | 5R01DC021133-04 |
| Project ID | NIH-11337542 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are adults experiencing or at risk for age-related hearing loss, or individuals with specific genetic profiles related to auditory function who may participate in future translational studies.
✕Less likely to help
People without age-related hearing loss or with unrelated hearing conditions may not benefit from this research.
What this research studies
This project uses an advanced AI pipeline to study mouse and human genes linked to hearing loss, aiming to identify genetic factors that contribute to aging of the auditory system. It will expand the AI’s capabilities to analyze structural genetic variations and to prioritize likely candidate genes for further study. The goal is to accelerate discoveries that could eventually lead to prevention or reversal options for age-related hearing loss in people. The research builds on well-established mouse models and looks for connections to human genes involved in hearing.
Why it matters
Potential benefit: If successful, the work could reveal new genetic targets and pathways to prevent or treat age-related hearing loss in humans.
How similar studies have gone: Prior mouse studies have linked genetic factors to hearing loss, and AI-based approaches are increasingly effective at prioritizing candidate genes.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Peltz, Gary a — Stanford University
- Study coordinator: Peltz, Gary a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.