ENACT: Integrated hearing and cognitive training for people with mild cognitive impairment
Official title: The Effect of the "Empowerment Network for Auditory-Cognitive Training (ENACT) Program" on Auditory Perception and Function, Cognitive Function and Health-related Quality of Life of Persons Living With Mild Cognitive Impairment
Run by The University of Hong Kong · NCT06955494 · Data updated 2026-11-12
This program tests whether adding online auditory training to cognitive training helps people with mild cognitive impairment who also have hearing loss.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 60 Years and up |
| Sex | All |
| Enrollment | 62 (estimated) |
| Sponsor | The University of Hong Kong Academic / other |
| Locations | 1 site (Hong Kong) |
| Status | Recruiting |
| Started | June 4, 2025 |
| Main results expected | November 30, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | November 2, 2026 |
| Trial ID | NCT06955494 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are people with mild cognitive impairment who have at least one-sided hearing impairment, own a smartphone, have an available primary caregiver, and have not had formal cognitive or auditory training in the past six months.
✕Probably not a fit
Patients with moderate or severe cognitive impairment, other significant sensory impairments, no smartphone access, or recent formal cognitive/auditory training are unlikely to receive benefit from this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
ENACT integrates auditory training into a standard cognitive-training program, delivered via smartphone-based modules with caregiver involvement and peer/goal-oriented supports to optimize engagement. Participants are adults with mild cognitive impairment by Petersen's criteria and at least one-sided hearing impairment on the integrated Digit-in-Noise (iDIN) test, while those with moderate/severe impairment or other sensory limitations are excluded. The intervention arm receives the ENACT program and the comparator receives usual care, with outcomes focused on auditory perception, cognitive function, and health-related quality of life. The program is administered through The University of Hong Kong and uses remote materials to facilitate participation.
Why it matters
Potential benefit: If successful, the program could improve everyday communication, strengthen attention and working memory, and help slow cognitive decline by jointly addressing hearing and cognitive deficits.
How similar studies have gone: Prior research indicates treating hearing loss can have secondary cognitive benefits, but combining structured auditory training directly into cognitive training as ENACT proposes is relatively novel and unproven.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Mild cognitive impairment accordingly to the Petersen's criteria * With at least one-side hearing impairment as defined by a score of 2- or 3- digit test greater than the norm value on the integrated Digit-in-Noise (iDIN test) * Has a smartphone to access the online training materials * Not received formal cognitive and auditory training in the past 6 months. * Available of primary caregiver in the family * give consent to participate Exclusion Criteria: * moderate and severe cognitive impairment * Other sensory impairment
Where it's running
-
The University of Hong Kong
Hong Kong, Hong Kong Recruiting
Study contacts
- Principal investigator: SAU FUNG DORIS YU, PhD — HKU School of Nursing
- Study coordinator: SAU FUNG DORIS YU, PhD
- Email: dyu1@hku.hk
- Phone: 852-39176319
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.