Better ways to find what causes hearing loss

What Causes Hearing Loss: Advancing the Methods

NIH-funded research Harvard University D/b/a Harvard School of Public Health · NIH-11370204

This project will create improved tools that combine hearing test patterns and people’s reports of their hearing to better understand hearing loss in adults.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHarvard University D/b/a Harvard School of Public Health NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11370204 on NIH RePORTER

What this research studies

From a patient perspective, researchers will look at the full shape of your audiogram across all frequencies instead of just an average hearing number. They will combine those audiogram patterns with self-reported hearing trouble and use new statistical and machine‑learning methods to find meaningful hearing phenotypes. The team will apply these methods to large existing US datasets (including NHS II, MUSC Hearing Study, and NHANES). They will also make user-friendly software so clinicians and researchers can use the new tools.

Who could benefit from this research

Good fit: Adults with measured audiograms or who report hearing problems—especially those enrolled in large health or hearing cohorts—are the kinds of people whose data this work focuses on.

Not a fit: People without audiometric testing or without any hearing complaints are unlikely to see direct benefit from this specific project.

Why it matters

Potential benefit: If successful, this work could let clinicians identify different types and causes of hearing loss more precisely, which could improve prevention and treatment choices.

How similar studies have performed: This builds on prior statistical work in hearing data, but integrating audiogram-shape analysis with self-report data and providing public software is a relatively new and novel approach.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.