Condition

Deafness clinical trials and research

• 12Clinical trials
• 13NIH research projects
• 5Countries

Newest Deafness clinical trials

All recruiting trials (12)

• Customizing cochlear implant programming based on inner ear nerve health

  This study tests whether tailoring cochlear implant programming to how healthy different parts of the hearing nerve are can improve understanding of speech in noisy environments.

  Recruiting Massachusetts Eye and Ear Infirmary · Boston, Massachusetts · NCT07683689

• Long-term hearing and speech outcomes after cochlear implants

  This project will see if cochlear implants improve hearing, speech understanding, and quality of life in Mandarin-speaking patients of all ages before and after surgery.

  Recruiting Eye & ENT Hospital of Fudan University · Shanghai · NCT07380269

• Reducing follow-up visits for cochlear implant patients using a new mapping strategy

  This study is testing a new way to program cochlear implants to see if adults can have fewer follow-up visits while still feeling satisfied and hearing well.

  Recruiting Massachusetts Eye and Ear Infirmary · Boston, Massachusetts · NCT06960616

• Cisplatin-related (Ear) Hearing Loss and Balance Issues in Head and Neck Cancer Patients

  This observational study tests whether hearing loss, tinnitus, and balance problems occur in head and neck cancer patients treated with cisplatin chemoradiotherapy compared with those receiving only radiotherapy, including optional genetic tests for susceptibility.

  Recruiting Paracelsus Medical University · Nuremberg, Bavaria · NCT06929468

• Early hearing loss detection in a memory clinic

  This project uses a VRB speech-in-noise test to try to detect hearing problems in people with mild to moderate cognitive impairment seen at a memory clinic.

  Recruiting University Hospital, Lille · Lille · NCT06088953

• Understanding how cochlear implants affect hearing in children and adults

  This study is trying to see how cochlear implants help both children and adults hear better and how they adjust to the changes over time.

  Recruiting at 2 sites Massachusetts Eye and Ear Infirmary · Boston, Massachusetts and 1 other locations · NCT05867173

• Investigating how cochlear and auditory brainstem implants affect hearing processing

  This study is testing how cochlear and auditory brainstem implants affect hearing and sound processing in both adults and children with hearing impairments.

  Recruiting NYU Langone Health · New York, New York · NCT05810220

• BEARS directional-listening training to improve hearing in older children and teens with two cochlear implants

  This trial tests whether 3 months of the BEARS virtual-reality directional listening training, added to usual care, helps 8–16 year olds with two cochlear implants hear better in noisy places, reduce listening effort, and improve vocabulary and quality of life.

  Recruiting at 12 sites Guy's and St Thomas' NHS Foundation Trust · Birmingham, Birmingham and 12 other locations · NCT05808543

• Collecting data and samples for research on hearing and communication disorders

  This study is collecting health information and samples from people aged 2 and up with hearing and communication disorders to help with future research on these issues.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT05670496

• Improving sound perception for children with cochlear implants

  This study is testing different ways to improve how children with cochlear implants hear sounds to see if it can help them hear better compared to kids with normal hearing.

  Recruiting NYU Langone Health · New York, New York · NCT05203302

• Evaluating auditory and cognitive functions in deaf children with cochlear implants

  This study tests how cochlear implants help young deaf children develop their hearing and thinking skills compared to children who can hear normally.

  Recruiting University Hospital, Toulouse · Toulouse · NCT04495660

• Registry and clinical study for Wolfram syndrome and related disorders

  This study is trying to gather information from people with Wolfram syndrome to better understand the condition and its effects, while also looking for specific gene mutations.

  Recruiting Washington University School of Medicine · St Louis, Missouri · NCT02841553

NIH-funded research (13)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• How microtubules help inner-ear hair cells develop and prevent deafness

  Researchers are looking at how a gene called Cep85l helps inner-ear hair cells build the tiny bundles needed for hearing, which could explain some inherited hearing loss.

  NIH research University of Virginia · Charlottesville, United States · NIH-11390842

• Gene therapy approach to Usher syndrome type 1F using compact PCDH15 in the inner ear

  A researcher team is developing a compact gene therapy using specially designed PCDH15 pieces delivered by AAV to the inner ear to help people with Usher syndrome type 1F.

  NIH research Massachusetts Eye and Ear Infirmary · Boston, United States · NIH-11370142

• New genes for early-onset hearing loss and precision medicine

  Researchers are trying to identify genetic causes of hearing loss present at birth or in early childhood to enable earlier, DNA-based diagnoses and future gene-based therapies.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11366340

• Optimizing how CI users hear in busy real-world environments

  This grant studies how to improve speech understanding and spatial hearing for people using cochlear implants, especially those with implants in both ears or with single-sided deafness.

  NIH research Univ of Maryland, College Park · College Park, United States · NIH-11336385

• Improving genetic testing for hearing loss

  This project works to make genetic test results clearer and more useful for people with inherited hearing loss.

  NIH research University of Iowa · Iowa City, United States · NIH-11287856

• How Usher-1 proteins in inner-ear hair cells affect hearing

  This project looks at how key Usher-1 proteins help tiny hair cells in the inner ear work and how problems in these proteins lead to inherited hearing and vision loss for people with Usher syndrome.

  NIH research West Virginia University · Morgantown, United States · NIH-11233313

• CRISPR-based exon-skipping to treat Usher syndrome deafness

  A gene-editing approach using CRISPR techniques to fix faulty exon regions in Usher syndrome patients to protect hearing and balance functions.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11125786

• Gene Therapy for Inherited Deafness and Blindness

  This work explores a new gene therapy to help people with Usher syndrome type 1F, a condition that causes profound deafness and progressive blindness.

  NIH research Massachusetts Eye and Ear Infirmary · Boston, United States · NIH-11105969

• Improving cochlear implants for better hearing in complex sound environments

  This study is looking to help people with hearing loss who use cochlear implants by figuring out how to make it easier for them to hear and understand speech in noisy places, so if you have trouble hearing in those situations, you might be able to join in and share your experiences!

  NIH research Univ of Maryland, College Park · College Park, United States · NIH-11099947

• Finding New Genetic Causes for Deafness Not Linked to Other Conditions

  This research aims to discover new genetic causes for hearing loss that is present at birth or develops early in life and is not part of a larger syndrome.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11097372

• Understanding how Usher proteins affect hearing and deafness

  This study is looking at how certain proteins in the tiny hair cells in our ears work together and how problems with them can lead to hearing loss, which could help us find new ways to treat deafness.

  NIH research West Virginia University · Morgantown, United States · NIH-11049994

• Cochlear implants for children with uneven hearing loss

  This study is looking at how cochlear implants can help children with uneven hearing or deafness in one ear, making it easier for them to hear and understand speech in busy places like schools and playgrounds.

  NIH research Washington University · Saint Louis, United States · NIH-10900721

• New treatments for inherited deaf-blindness caused by Usher syndrome

  This study is exploring new ways to help people with Usher syndrome, which causes both hearing and vision loss, by using a special technology to fix the genes that are causing these issues, and patients might even get a chance to be part of this exciting research that could lead to better treatments.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-10876488

Related topics

Quick answers

How many Deafness clinical trials are recruiting right now?

12, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (7 trials), France (2 trials), Germany (1 trial), United Kingdom (1 trial), China (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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