Condition

Giant Cell Arteritis clinical trials and research

• 21Clinical trials
• 4NIH research projects
• 10Countries

Newest Giant Cell Arteritis clinical trials

All recruiting trials (21)

• How optic nerve swelling changes after starting steroids in giant cell arteritis

  This study tests how quickly the optic nerve sheath swelling decreases after starting glucocorticoids in people with newly diagnosed giant cell arteritis.

  Recruiting Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal · Montreal, Quebec · NCT07508514

• Precision care for giant cell arteritis and polymyalgia rheumatica

  This long-term observational project will follow adults with giant cell arteritis or polymyalgia rheumatica to see if regular imaging, eye exams, blood tests, and immune cell profiling can better predict aortic complications and steroid side effects over 5–10 years.

  Recruiting Wuerzburg University Hospital · Würzburg · NCT07084480

• Ultrasound lesions in temporal and axillary arteries and relapse risk in giant cell arteritis.

  We will test whether lesions seen on ultrasound of the temporal and axillary arteries can predict relapse in people with giant cell arteritis.

  Recruiting at 2 sites University Hospital, Brest · Brest and 1 other locations · NCT06894602

• Understanding how Giant Cell Arteritis affects vision

  This study is trying to understand how Giant Cell Arteritis affects vision in adults by comparing eye health in those with GCA-related vision problems to those with other causes of vision loss.

  Recruiting ASST Fatebenefratelli Sacco · Milan, Lombardy · NCT06500728

• Understanding biomarkers in giant cell arteritis and polymyalgia rheumatica

  This study is trying to find specific markers in the blood of people newly diagnosed with giant cell arteritis and polymyalgia rheumatica to help doctors understand their disease better and create personalized treatment plans.

  Recruiting University of Bonn · Bonn, North Rhine-Westphalia · NCT06460142

• Investigating a new imaging tracer for diagnosing giant cell arteritis

  This study is testing a new imaging method called AzaFol-PET/CT to see if it can better diagnose giant cell arteritis in people aged 50 and older compared to the current standard method.

  Recruiting Phase 2 Insel Gruppe AG, University Hospital Bern · Bern · NCT06335888

• Exploring how the gut microbiome affects giant cell arteritis

  This study looks at how the bacteria in the gut might affect people with giant cell arteritis to see if they can find clues for better treatments.

  Recruiting at 2 sites University of Bonn · Bonn, North Rhine-Westphalia and 1 other locations · NCT06279065

• Evaluating imaging methods for diagnosing Giant Cell Arteritis

  This study is testing whether non-invasive imaging methods like MRI and ultrasound can help diagnose Giant Cell Arteritis better than the usual biopsy.

  Recruiting Fondation Ophtalmologique Adolphe de Rothschild · Paris · NCT06004154

• National database for Giant Cell Arteritis and Polymyalgia Rheumatica

  This study is trying to see how new imaging techniques can help doctors better manage Giant Cell Arteritis and Polymyalgia Rheumatica by looking at treatment responses and risks in patients.

  Recruiting at 2 sites University of Aarhus · Aarhus and 1 other locations · NCT05935709

• Nationwide registry for systemic autoimmune and autoinflammatory diseases in Armenia

  This study is trying to gather information about systemic autoimmune and autoinflammatory diseases in Armenia to better understand how these conditions progress and how they are treated.

  Recruiting at 4 sites Santé Arménie French-Armenian Research Center · Yerevan and 5 other locations · NCT05904301

• Using MRI to detect inflammation in giant cell arteritis

  This study is testing if MRI scans can help find inflammation in the arteries of people with giant cell arteritis.

  Recruiting at 2 sites University of Pennsylvania · Rochester, Minnesota and 3 other locations · NCT05865054

• How MRI spatial resolution affects detection of giant cell arteritis

  This project will test whether different contrast-enhanced 3D T1 MRI sequences with varied spatial resolution better detect giant cell arteritis in adults who are suspected of having it.

  Recruiting Fondation Ophtalmologique Adolphe de Rothschild · Paris · NCT05854927

• Optic nerve sheath ultrasound to diagnose and monitor giant cell arteritis

  This research will test whether measuring the optic nerve sheath diameter with ultrasound can help diagnose and monitor new-onset giant cell arteritis in people over 50 referred for suspected disease.

  Recruiting Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal · London, Ontario and 6 other locations · NCT05749094

• Supplemental hydrocortisone for adrenal insufficiency during stress

  This study is testing if adding hydrocortisone can help people with polymyalgia rheumatica or giant cell arteritis who have low adrenal function feel better during stressful times compared to a placebo.

  Recruiting at 3 sites Phase 4 Copenhagen University Hospital, Rigshospitalet · Aarhus and 2 other locations · NCT05435781

• Using abatacept to treat Giant Cell Arteritis

  This study is testing whether a medication called abatacept can help people with newly diagnosed or relapsing Giant Cell Arteritis feel better and achieve remission.

  Recruiting at 9 sites Phase 3 University of Pennsylvania · Rochester, Minnesota and 9 other locations · NCT04474847

• Registry and biorepository for rheumatic diseases

  This study is collecting samples and health information from adults with rheumatic diseases at Yale clinics to help researchers learn more about these conditions and improve future treatments.

  Recruiting Yale University · New Haven, Connecticut · NCT04402086

• Understanding genetic factors in Giant Cell Arteritis and Polymyalgia Rheumatica

  This study is trying to find out if certain genes make people more likely to get Giant Cell Arteritis or Polymyalgia Rheumatica, focusing on patients aged 50 and older who have these conditions.

  Recruiting at 61 sites University of Leeds · Canterbury, Kent and 75 other locations · NCT04102930

• Giant Cell Arteritis: Comparing a Shorter vs. Longer Corticosteroid Taper

  This study tests whether a shorter, lighter corticosteroid taper works as well as the standard longer taper for people with giant cell arteritis.

  Recruiting Phase 3 University Hospital, Caen · Caen · NCT04012905

• Collection of tissue samples for vasculitis research

  This study is collecting tissue samples from patients with vasculitis to see if they can help researchers understand the disease better and find new ways to diagnose and treat it.

  Recruiting at 3 sites University of Pennsylvania · Boston, Massachusetts and 7 other locations · NCT02967068

• Understanding the natural history and outcomes of systemic vasculitis

  This study is trying to understand how systemic vasculitis affects people over time and what signs can help predict how the disease will progress, involving both patients with vasculitis and healthy volunteers.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT02257866

• One-time DNA analysis for vasculitis

  This study is testing whether analyzing DNA from people with different types of vasculitis can help find genetic factors that increase the risk of these diseases and lead to better treatments.

  Recruiting at 4 sites University of Pennsylvania · Los Angeles, California and 13 other locations · NCT01241305

NIH-funded research (4)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• T Cell Immunity in Giant Cell Arteritis

  A study at Mayo Clinic Rochester is looking at how specific immune signals go wrong in giant cell arteritis to better understand why it damages the aorta and its vessels.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11327645

• MRI scans to detect artery and eye inflammation in giant cell arteritis

  This work uses combined orbital and cranial vessel-wall MRI to find artery and eye inflammation in people with giant cell arteritis.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11231724

• Using MRI to improve diagnosis and treatment of giant cell arteritis

  This study is testing a new type of MRI that looks closely at the blood vessels in your head to help doctors better understand and treat giant cell arteritis, which can cause vision problems, so you can get the right care without taking extra medications that might not be needed.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11048091

• Understanding T cell immunity in a type of blood vessel inflammation

  This study is looking at Giant Cell Arteritis (GCA) to understand why the immune system goes into overdrive and how that can cause serious problems, with the hope of finding new ways to help people with this condition.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-10992659

Related topics

Quick answers

How many Giant Cell Arteritis clinical trials are recruiting right now?

21, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in Canada (6 trials), United States (6 trials), Germany (5 trials), France (4 trials), Denmark (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Phase 4: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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