Precision care for giant cell arteritis and polymyalgia rheumatica

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a non-interventional cohort study enrolling adults with a primary diagnosis of giant cell arteritis (GCA) or polymyalgia rheumatica (PMR) for long-term follow-up. Participants will undergo standardized clinical exams, serial imaging (including MRI and orbital MRI with OCT), serologic testing, and immunophenotyping to identify prognostic factors and patient clusters. The protocol includes evaluation of a contrast-sparing MRI technique and focused searches for rare lymphocyte populations that might predict recurrence or treatment response. Outcomes of interest are aortic aneurysms/dissections and glucocorticoid-associated adverse events over a 5–10 year period.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age greater or similar to 18 years
* Primary diagnosis of GCA or PMR

Exclusion Criteria:

* Age under 18 years
* lack of capacity to consent

Where it's running

• Universitätsklinikum Würzburg
  Würzburg, Germany Recruiting

Study contacts

• Principal investigator: Michael Gernert — Wuerzburg University Hospital
• Study coordinator: Michael Gernert
• Email: gernert_m1@ukw.de
• Phone: +4993120140100

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Understanding biomarkers in giant cell arteritis and polymyalgia rheumatica

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• Investigating a new imaging tracer for diagnosing giant cell arteritis

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• Exploring how the gut microbiome affects giant cell arteritis

  This study looks at how the bacteria in the gut might affect people with giant cell arteritis to see if they can find clues for better treatments.

  Recruiting at 2 sites University of Bonn · Bonn, North Rhine-Westphalia and 1 other locations · NCT06279065

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.