Evaluating imaging methods for diagnosing Giant Cell Arteritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients diagnosed with Giant Cell Arteritis (GCA), also known as Horton's disease, which can lead to serious complications if not diagnosed and treated promptly. The study aims to assess the effectiveness of non-invasive imaging techniques, such as MRI and ultrasound, as alternatives to the traditional temporal artery biopsy for diagnosing GCA. By utilizing these imaging methods, the study seeks to improve diagnostic accuracy and reduce the need for invasive procedures. Participants will be monitored to evaluate the outcomes of these imaging evaluations in the context of their GCA diagnosis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient aged 50 and over
* Having received informed consent to participate in the study
* Affiliated or beneficiary of a social insurance scheme
* Patients with giant cell arteritis according to ACR/EULAR 2022 criteria
* Diagnosed with MRI and ultrasound.

Exclusion Criteria:

* Absolute or relative contraindication to MRI (incompatible implantable device, claustrophobia, etc.)
* Hypersensitivity to gadobutrol
* Patient under legal protection
* Pregnant or breast-feeding women

Where it's running

• Hopital Fondation Adolphe de Rothschild
  Paris, France Recruiting

Study contacts

• Study coordinator: Amélie Yavchitz, PhD
• Email: ayavchitz@for.paris
• Phone: 0148036454

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• How optic nerve swelling changes after starting steroids in giant cell arteritis

  This study tests how quickly the optic nerve sheath swelling decreases after starting glucocorticoids in people with newly diagnosed giant cell arteritis.

  Recruiting Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal · Montreal, Quebec · NCT07508514

• Precision care for giant cell arteritis and polymyalgia rheumatica

  This long-term observational project will follow adults with giant cell arteritis or polymyalgia rheumatica to see if regular imaging, eye exams, blood tests, and immune cell profiling can better predict aortic complications and steroid side effects over 5–10 years.

  Recruiting Wuerzburg University Hospital · Würzburg · NCT07084480

• Ultrasound lesions in temporal and axillary arteries and relapse risk in giant cell arteritis.

  We will test whether lesions seen on ultrasound of the temporal and axillary arteries can predict relapse in people with giant cell arteritis.

  Recruiting at 2 sites University Hospital, Brest · Brest and 1 other locations · NCT06894602

• Understanding how Giant Cell Arteritis affects vision

  This study is trying to understand how Giant Cell Arteritis affects vision in adults by comparing eye health in those with GCA-related vision problems to those with other causes of vision loss.

  Recruiting ASST Fatebenefratelli Sacco · Milan, Lombardy · NCT06500728

• Understanding biomarkers in giant cell arteritis and polymyalgia rheumatica

  This study is trying to find specific markers in the blood of people newly diagnosed with giant cell arteritis and polymyalgia rheumatica to help doctors understand their disease better and create personalized treatment plans.

  Recruiting University of Bonn · Bonn, North Rhine-Westphalia · NCT06460142

• Investigating a new imaging tracer for diagnosing giant cell arteritis

  This study is testing a new imaging method called AzaFol-PET/CT to see if it can better diagnose giant cell arteritis in people aged 50 and older compared to the current standard method.

  Recruiting Phase 2 Insel Gruppe AG, University Hospital Bern · Bern · NCT06335888

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.