Assessing genetic and molecular profiles in health and disease in the Czech population
Official title: Assesment of Multiomics Profiles in Health and Disease - Corelation With the Disease Phenotype.
Run by The Institute of Molecular and Translational Medicine, Czech Republic · NCT04427163 · Data updated 2026-11-12
This study is trying to gather genetic and health information from 10,000 people in the Czech Republic, both healthy and those with diseases, to help better understand health issues in the region.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 68 Years |
| Sex | All |
| Enrollment | 1100 (estimated) |
| Sponsor | The Institute of Molecular and Translational Medicine, Czech Republic Academic / other |
| Locations | 1 site (Olomouc) |
| Status | Recruiting |
| Started | September 1, 2018 |
| Main results expected | September 1, 2028 |
| Study ends | March 30, 2029 |
| Registry record updated | February 13, 2026 |
| Trial ID | NCT04427163 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are healthy individuals aged 18 to 68 without a genetic predisposition to disease or significant health issues.
✕Probably not a fit
Patients with existing genetically dependent diseases or significant health conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to establish reference genomic, transcriptomic, proteomic, and metabolomic profiles within the Czech population. Initially involving 1,000 healthy volunteers, the study plans to expand to 10,000 participants, including both healthy individuals and patients with various diseases. By creating a comprehensive reference database, the study seeks to enhance the interpretation of pathological findings in patients, particularly in the context of the unique genetic and environmental factors present in Central Europe. Participants will also have the opportunity to contribute biological samples for future research.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into disease predisposition and improve disease diagnosis and management for patients.
How similar studies have gone: While similar studies have been conducted in other populations, this approach is novel for the Czech and Slavic populations, making it a unique contribution to the field.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * age 18 - 68 years * (for the first 1100 subjects): * healthy volunteers without genetically dependent disease and without such a disease in a family * healthy volunteer without the preliminary evidence of civilizational diseases such as hypertension, diabetes, autoimmune and tumor diseases or acute infectional diseases; clinically manifesting cardiovascular or pulmonary disability. * subject without permanent of long-term medication in the time of biological sampling. Exclusion Criteria: * not complying with inclusion criteria
Where it's running
-
University Hospital Olomouc
Olomouc, Czechia Recruiting
Study contacts
- Study coordinator: Marian Hajduch, MD, PhD.
- Email: marian.hajduch@upol.cz
- Phone: +420585632083
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.