Testing for cancer risk genes in children with newly diagnosed cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study assesses the effectiveness of family-based whole-genome sequencing (WGS) to identify cancer predisposition syndromes in children and adolescents newly diagnosed with cancer. By analyzing the genetic information of the patient and their family, the study aims to uncover germline mutations that may increase cancer risk. The research will evaluate the clinical benefits of this approach compared to traditional predictive methods, focusing on its impact on patient care and genetic counseling. The study also aims to explore the psychosocial effects of genetic testing on patients and their families.

Why it matters

Who can join: the full rules

* New diagnosis of malignancy
* Age ≤ 21 years
* Written informed consent

Psychosocial component:

* Participants (≥ 12 years)
* Parent/caregiver(s) of participants
* Healthcare professionals involved in the care of patients enrolled in the study

Where it's running

• John Hunter Children's Hospital
  Newcastle, New South Wales, Australia Recruiting
• Sydney Children's Hospital
  Sydney, New South Wales, Australia Recruiting
• The Children's Hospital at Westmead
  Sydney, New South Wales, Australia Recruiting

Study contacts

• Study coordinator: Clinical Trials Manager
• Email: SCHN-PREDICT@health.nsw.gov.au
• Phone: +61 2 9382 3122

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.