Combined Mulligan Mobilization, Pain Neuroscience Education, and Core Stabilization for Frozen Shoulder
Official title: The Combined Effect of Mulligan Mobilization, Pain Neuroscience-Based Training, and Core Stabilization Exercises in Frozen Shoulder Patients
Run by Yeditepe University · NCT07667556 · Data updated 2026-11-12
This study tests whether a rehab program with Mulligan mobilization, pain education, and core stabilization helps people with frozen shoulder more than standard physical therapy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 36 (estimated) |
| Sponsor | Yeditepe University Academic / other |
| Locations | 1 site (Istanbul) |
| Status | Recruiting |
| Started | April 21, 2026 |
| Main results expected | January 2027 |
| Study ends | January 2027 |
| Registry record updated | August 4, 2026 |
| Trial ID | NCT07667556 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–65 with a clinical diagnosis of adhesive capsulitis and the ability to participate in education and exercise sessions.
✕Probably not a fit
Individuals who do not respond to the combined approach or who have contraindications to the interventions may not experience additional benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized trial compares a combined rehabilitation program—Mulligan Mobilization with Movement, Pain Neuroscience Education, and core stabilization exercises—to conventional physical therapy in adults with adhesive capsulitis. Outcomes include pain, shoulder range of motion, function, quality of life, scapular movement, and pain catastrophizing. Participants are adults 18–65 diagnosed with adhesive capsulitis and able to consent and attend sessions. The trial aims to determine if the combined approach offers added benefits over standard therapy, with evaluations at planned time points. The study is led by Yeditepe University with sites in Istanbul, Turkey.
Why it matters
Potential benefit: If successful, participants may experience greater pain relief and improved shoulder mobility and function compared with standard therapy.
How similar studies have gone: Previous work supports Mulligan mobilization for pain and function in frozen shoulder, but evidence for Pain Neuroscience Education and DNS-based core stabilization in this condition is limited, making this approach novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18 to 65 years * Diagnosis of adhesive capsulitis confirmed by an orthopedic surgeon or a physical medicine and rehabilitation physician * Presence of shoulder pain and limitation of shoulder range of motion * Ability to communicate verbally * Ability to understand study procedures and educational content * Willingness to participate and provide written informed consent * Mini-Mental State Examination (MMSE) score of 24 or higher * Ability to attend treatment and assessment sessions regularly Exclusion Criteria: * MMSE score below 24 * Severe cognitive impairment * Severe psychiatric disorders * Active infectious disease * Active malignancy * Uncontrolled cardiovascular disease * Presence of a cardiac pacemaker * Contraindications to transcutaneous electrical nerve stimulation (TENS) * Neurological disorders that may affect participation or outcomes * Systemic diseases that may interfere with the safe implementation of the intervention * Inability to comply with the study protocol or attend scheduled sessions
Where it's running
-
Life Med Tıp Merkezi
Istanbul, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Dilay Döner
- Email: dilay.doner@std.yeditepe.edu.tr
- Phone: +90 0535 019 58 83
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.