Using relaxin to treat frozen shoulder
Enabling Studies for the Treatment of Frozen Shoulder Using Relaxin
['FUNDING_SBIR_2'] · ORTHOLEVO, INC. · NIH-10448418
This study is testing a new injection treatment for frozen shoulder that uses a natural hormone to help ease pain and stiffness, aiming to improve your shoulder movement and overall quality of life.
Quick facts
| Phase | ['FUNDING_SBIR_2'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ORTHOLEVO, INC. (nih funded) |
| Locations | 1 site (Lynnfield, UNITED STATES) |
| Trial ID | NIH-10448418 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a new treatment for frozen shoulder, a condition that causes painful stiffness and limited motion in the shoulder. The approach involves creating a local injectable formulation of relaxin-2, a naturally occurring hormone that helps reduce collagen production and promote tissue remodeling. By targeting the underlying cause of the condition, this therapy aims to provide more effective and lasting relief compared to current treatments. Patients will receive this innovative therapy through injections, which could significantly improve their shoulder mobility and quality of life.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with frozen shoulder who are experiencing significant pain and limited range of motion.
Not a fit: Patients with frozen shoulder who have already undergone surgical treatment or those with other underlying shoulder conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a novel and effective treatment option for patients suffering from frozen shoulder, potentially reducing the need for surgical interventions.
How similar studies have performed: While the use of relaxin for treating frozen shoulder is a novel approach, similar hormone-based therapies have shown promise in other fibrotic conditions, indicating potential for success.
Where this research is happening
Lynnfield, UNITED STATES
- ORTHOLEVO, INC. — Lynnfield, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: COOPER, BENJAMIN GOLDMAN — ORTHOLEVO, INC.
- Study coordinator: COOPER, BENJAMIN GOLDMAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.