Condition

Dilated Cardiomyopathy (DCM) clinical trials and research

• 13Clinical trials
• 6Countries

Newest Dilated Cardiomyopathy (DCM) clinical trials

All recruiting trials (13)

• Second infusion of FAP-targeted iCDC for end-stage dilated cardiomyopathy

  This study tests whether a second dose of FAP-targeted immunosuppressive CAR-DC therapy can safely improve heart function in adults with end-stage dilated cardiomyopathy who previously had a partial response.

  Recruiting Phase 1 Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou, Zhejiang / 浙江 · NCT07516288

• AAV Gene Therapy for BAG3-Related Dilated Cardiomyopathy in Adults

  This Phase 1/2 trial tests a single IV dose of AFTX-201 to see if it is safe and potentially helps adults with BAG3-related dilated cardiomyopathy.

  Recruiting at 5 sites Phase 1/2 Affinia Therapeutics · Miami, Florida and 4 other locations · NCT07426419

• Monitoring progression of chronic cardiovascular conditions

  This project will collect wearable physiologic data from adults with cardiovascular conditions to see how their heart disease changes over time.

  Recruiting Prolaio · Chicago, Illinois · NCT07420907

• Multimodal analysis of heart biopsy samples

  This project will take one extra small heart biopsy during a clinically needed procedure to test whether detailed molecular and immune analyses can find disease-specific signatures in adults with cardiomyopathies, myocarditis, cardiac amyloidosis, or after heart transplant.

  Recruiting University Hospital, Essen · Essen, North Rhine-Westphalia · NCT07359690

• T1 mapping to characterize heart tissue in common heart diseases

  This project tests whether T1 mapping MRI scans, including dye-free native T1, can define normal and disease-specific heart tissue values for adults with various heart conditions.

  Recruiting Chinese Academy of Medical Sciences, Fuwai Hospital · Beijing, Beijing Municipality · NCT07354646

• Endocardial delivery of stem-cell derived heart cells to help severe heart failure

  This study tests endocardial delivery of HS-001 cell sheets made from iPSC-derived cardiomyocytes in adults with severe heart failure and reduced ejection fraction to see if it is safe and may improve heart function over 26 weeks.

  Recruiting at 5 sites Phase 1/2 Heartseed Inc. · Tsukuba, Ibaraki and 4 other locations · NCT07347197

• Do tiny coronary blood vessel problems affect outcomes in dilated cardiomyopathy?

  This project will test whether coronary microvascular dysfunction changes long-term outcomes for people with dilated cardiomyopathy.

  Recruiting Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou, Zhejiang · NCT07293338

• UIC multi-ethnic dilated cardiomyopathy registry

  This project will collect genetic and social data from adults with dilated cardiomyopathy, especially African American and Hispanic/Latino patients, to see if certain genes and social factors explain worse outcomes.

  Recruiting University of Illinois Chicago · Chicago, Illinois · NCT07145138

• RP-A701 gene therapy for BAG3-related dilated cardiomyopathy

  This Phase 1 study will try a one-time intravenous RP-A701 gene therapy in adults with BAG3-related dilated cardiomyopathy to see if it is safe and may improve heart function.

  Recruiting at 3 sites Phase 1 Rocket Pharmaceuticals Inc. · San Diego, California and 2 other locations · NCT07137338

• Protein A immunoadsorption for dilated cardiomyopathy with anti–β1-adrenergic receptor antibodies

  This trial tests whether Protein A immunoadsorption can improve heart function and outcomes in adults with dilated cardiomyopathy who have anti–β1-adrenergic receptor antibodies.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06922851

• FAP-targeted immunosuppressive CAR-DC therapy for end-stage dilated cardiomyopathy

  Researchers are testing a new immune-cell therapy to see if it’s safe and helps people with end-stage dilated cardiomyopathy.

  Recruiting Phase 1/2 Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou, Zhejiang · NCT06902896

• Evaluating the impact of specific antibodies in patients with dilated cardiomyopathy

  This study is trying to see if certain antibodies in people with dilated cardiomyopathy can help predict their heart health and outcomes over three years.

  Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Wuhan, Hubei · NCT06741995

• Registry for patients with non-ischemic cardiomyopathies

  This study is collecting information from people with non-ischemic cardiomyopathies to see how to better diagnose and manage their condition and predict potential heart rhythm problems.

  Recruiting Scientific Institute San Raffaele · Milan, Milano · NCT06607471

Related topics

Quick answers

How many Dilated Cardiomyopathy (DCM) clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in China (6 trials), United States (4 trials), Germany (1 trial), Italy (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 3, Phase 1: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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