Condition
Chronic Respiratory Failure clinical trials and research
As of November 12, 2026, Find a Trial lists 7 Chronic Respiratory Failure clinical trials that are recruiting, at sites in 5 countries (most in Italy (2), Turkey (Türkiye) (2), United States (1)). By phase: Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 7Clinical trials
- 5Countries
Newest Chronic Respiratory Failure clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Turkish version of the S3-NIV questionnaire: testing its reliability for home NIV patients | — | Istanbul | Recruiting | May 27, 2026 |
| Extra oxygen during the 6-minute walk for people with chronic respiratory failure or exercise-related low oxygen | — | Lumezzane, Brescia and 5 other locations | Recruiting | Mar 5, 2026 |
| Machine learning to detect inspiratory leak in long-term non-invasive ventilation | — | Oslo | Recruiting | Feb 24, 2026 |
| Home oxygen with high-flow therapy vs standard oxygen for chronic lung and heart disease | — | Ferrara, Italy | Recruiting | Sep 5, 2025 |
| Early Non-Invasive Ventilation in ALS | Phase 2 | Hershey, Pennsylvania and 2 other locations | Recruiting | Jul 17, 2025 |
| Comparing closed-loop synchronization to conventional synchronization in noninvasive ventilation for breathing patients | — | Izmir | Recruiting | Apr 10, 2024 |
| Improving home ventilation for chronic respiratory failure patients | — | Groningen | Recruiting | Mar 6, 2023 |
All recruiting trials (7)
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Turkish version of the S3-NIV questionnaire: testing its reliability for home NIV patients
We’re testing whether the Turkish S3-NIV questionnaire reliably measures how well patients on home non-invasive ventilation can manage daily use and comfort.
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Extra oxygen during the 6-minute walk for people with chronic respiratory failure or exercise-related low oxygen
This trial will test whether giving extra oxygen during a 6-minute walk helps people with chronic respiratory failure or exertional low oxygen from COPD or interstitial lung disease walk farther, breathe better, and feel easier during the test.
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Machine learning to detect inspiratory leak in long-term non-invasive ventilation
This project tries to use a machine-learning program to detect inspiratory leaks in people with chronic respiratory failure who use long-term non-invasive ventilation.
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Home oxygen with high-flow therapy vs standard oxygen for chronic lung and heart disease
In people with long-term lung or heart conditions who need oxygen after leaving the hospital, the study tests whether a high-flow nasal cannula (HFNC) can improve breathing comfort and quality of life compared with standard oxygen therapy.
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Early Non-Invasive Ventilation in ALS
This study tests whether starting non-invasive ventilation earlier in adults with ALS can help improve breathing and quality of life.
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Comparing closed-loop synchronization to conventional synchronization in noninvasive ventilation for breathing patients
This study is testing if a new automatic breathing device helps adults using noninvasive ventilation breathe better compared to standard methods.
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Improving home ventilation for chronic respiratory failure patients
This study is testing a new way to monitor patients with chronic respiratory failure who use home ventilation to see if it improves their breathing comfort and effectiveness.
Related topics
Quick answers
How many Chronic Respiratory Failure clinical trials are recruiting right now?
7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 5 countries. The most sites are in Italy (2 trials), Turkey (Türkiye) (2 trials), United States (1 trial), Norway (1 trial), Netherlands (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.