Improving home ventilation for chronic respiratory failure patients

Improving Chronic Nocturnal Noninvasive Ventilation: a Multimodality Approach

Observational University Medical Center Groningen · NCT05756387

This study is testing a new way to monitor patients with chronic respiratory failure who use home ventilation to see if it improves their breathing comfort and effectiveness.

Quick facts

Study typeObservational
Enrollment100 (estimated)
SexAll
SponsorUniversity Medical Center Groningen Academic / other
Locations1 site (Groningen)
Trial IDNCT05756387 on ClinicalTrials.gov

What this trial studies

This observational study aims to develop a reliable method for remotely monitoring patients on chronic home non-invasive ventilation (NIV). It will assess ventilatory efficacy and patient comfort by collecting data on gas exchange, lung mechanics, and patient-ventilator interaction. The study will create a databank of synchronously acquired datasets from standard care monitored parameters and newly acquired non-invasive data on patient effort and lung inflation during NIV setup and follow-up.

Who should consider this trial

Good fit: Ideal candidates for this study are COPD patients who require chronic home non-invasive ventilation.

Not a fit: Patients who are unable to read the consent form or cannot perform measurements at home may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance the management of chronic respiratory failure, leading to improved patient outcomes and comfort.

How similar studies have performed: Other studies have shown promise in improving patient outcomes with similar monitoring approaches, indicating potential for success in this study.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* COPD patients indicated for chronic home NIV

Exclusion Criteria:

* not able to read the written information and/or sign the informed consent form
* no possibility to perfrom measurements at home

Where this trial is running

Groningen

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic Respiratory FailureNon-invasive VentilationMonitoring
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.