Air filters at home to see if breathing cleaner air helps heart health in obesity

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot interventional study examines if lowering PM2.5 exposure with portable air filtration systems improves cardiovascular risk markers in people with obesity and hypertension. It also explores whether antioxidant levels influence the link between PM2.5 exposure and blood pressure. The intervention uses sham devices as a control to assess any true physiological benefit. The study aims to provide evidence on the feasibility and potential impact of using home air filtration to reduce CV risk in obesity. If successful, results could support broader adoption of personal air filtration strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* ≥21 years old
* diagnosis of hypertension (BP ≥140/90 mm Hg)
* obesity (BMI\>30)

Exclusion Criteria:

* any CV event (myocardial infarction, stroke, heart failure) in the past 3 months
* unstable CV condition (class 3-4 angina or heart failure) or any medical condition that would place the subject at risk from participation or jeopardize study integrity (per investigators)
* expected overnight travel outside their home during the 9-week study period
* unable to comprehend/sign informed consent
* lung disease requiring oxygen
* cancer receiving active treatment or chemotherapy
* CPAP use for sleep apnea
* CV medication change in the prior month

Where it's running

• Michigan State University
  East Lansing, Michigan, United States Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.