Condition

Cardiometabolic Risk Factors clinical trials and research

• 12Clinical trials
• 7NIH research projects
• 10Countries

Newest Cardiometabolic Risk Factors clinical trials

All recruiting trials (12)

• Cardiorespiratory and muscular fitness in children with obesity and autism

  This study tests whether cardiorespiratory fitness and handgrip strength differ between children with obesity who have autism and those who do not, and how these fitness measures relate to body size, composition, and cardiometabolic health.

  Recruiting University of Virginia · Charlottesville, Virginia · NCT07804680

• Muscle features linked to insulin resistance and cardiometabolic risk

  This study tests whether specific muscle traits and activity patterns can help explain insulin resistance and related cardiometabolic risk in healthy adults.

  Recruiting University Ghent · Ghent, East Flanders · NCT07678736

• Health effects of ultra-processed foods on appetite and cardiometabolic health

  This study tests whether a high ultra-processed food diet affects appetite and cardiometabolic health compared with a nutrient-matched low ultra-processed diet in adults who keep their weight stable.

  Recruiting Göteborg University · Gothenburg · NCT07634159

• Low-dose semaglutide for weight loss in obese Pakistani adults

  This study will see if once-weekly low-dose semaglutide plus lifestyle counseling helps obese Pakistani adults without diabetes lose weight over 24 weeks.

  Recruiting Phase 4 Asian Institute Of Medical Sciences · Hyderābād, Sindh · NCT07513168

• Ginger capsules for inflammation, oxidative stress, and blood vessel health

  This trial will test whether taking a daily ginger capsule for 60 days can lower inflammation and oxidative stress and improve blood vessel function in adults with excess body fat.

  Recruiting Universidad Católica San Antonio de Murcia · Murcia, Murcia · NCT07437222

• Probiotic supplement plus lifestyle changes for fatty liver (MASLD)

  This trial will test whether taking a probiotic supplement alongside lifestyle changes can reduce liver fat, improve liver tests, and improve metabolic health in adults with MASLD.

  Recruiting Fu Jen Catholic University Hospital · New Taipei City and 1 other locations · NCT07400367

• Five weight‑neutral online programs to support healthy eating, activity, and body appreciation for adults with higher body weight

  This project will test five different online group programs that combine Mediterranean‑style eating, physical activity guidance, mindful eating, body acceptance, and enjoyable exercise for adults with BMI 25–40 to see which programs people like and stick with.

  Recruiting The Miriam Hospital · Providence, Rhode Island · NCT07363616

• Diastolic improvement with carvedilol and empagliflozin for people with cirrhosis

  This test will see if adding empagliflozin to carvedilol improves diastolic heart function and reduces decompensation events in adults with cirrhosis and left ventricular diastolic dysfunction.

  Recruiting Phase 4 Post Graduate Institute of Medical Education and Research, Chandigarh · Chandigarh · NCT07322237

• Whey protein–enriched milk fat globule membrane added to a high‑fat meal to see short‑term heart and brain effects in postmenopausal women

  This trial will test whether adding a whey protein–enriched milk fat globule membrane powder to a high‑fat meal changes short‑term heart and brain health markers in postmenopausal women with overweight and moderate cardiovascular risk.

  Recruiting Loughborough University · Loughborough, Leicestershire · NCT06953232

• Exploring the Asian-Mediterranean diet's impact on women's health

  This study is testing whether a Mediterranean-style diet designed for Asian women can improve heart and metabolic health in women aged 21-50 in Singapore.

  Recruiting Global Centre for Asian Women's Health · Singapore, Singapore · NCT06825936

• Short post-meal activity and spread-out exercise for breast cancer survivors

  We will test whether short bouts of activity after meals or spreading activity through the day better lower blood sugar than no activity or a standard 30‑minute workout in sedentary, postmenopausal breast cancer survivors on aromatase inhibitors and similar women without cancer.

  Recruiting University of Toronto · Toronto, Ontario · NCT06633380

• Breaking up long periods of sitting to improve heart and metabolic health

  This study is testing how often and how long people should take breaks from sitting to see if it can help improve their heart and metabolic health.

  Recruiting Columbia University · New York, New York · NCT05353322

NIH-funded research (7)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Obesity and GLP-1 treatment in young people with type 1 diabetes

  A study in teens and young adults with type 1 diabetes and obesity will look at how a GLP-1–based obesity medicine affects body fat distribution, insulin resistance, and lipids.

  NIH research Yale University · New Haven, United States · NIH-11370619

• Understanding and treating obesity in young people with type 1 diabetes

  This research explores how a medication for obesity, called a GLP-1 analogue, helps young people with type 1 diabetes manage their weight and reduce heart-related health risks.

  NIH research Yale University · New Haven, United States · NIH-11126759

• Investigating the impact of fat around the heart on diabetes and heart health in young people undergoing weight loss surgery

  This study is looking at how the fat around the heart affects heart health in teenagers with type 2 diabetes who are having weight loss surgery, using special heart scans to find out more about it and see how different diabetes treatments might help.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11061185

• How pre-pregnancy health affects pregnancy complications and heart health later on

  This study is looking at how health issues like being overweight or having high blood pressure before pregnancy might lead to preeclampsia, a serious condition during pregnancy, and it aims to find out how these factors can affect heart health for women after they give birth, so we can improve care and prevention for t

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11014058

• Investigating the effects of a medication for obesity on heart and metabolic health in young people with type 1 diabetes

  This study is looking at how a special medication can help young people with type 1 diabetes manage their weight and improve their health, by checking things like body fat and how their bodies use insulin.

  NIH research Yale University · New Haven, United States · NIH-10898805

• Improving sleep to reduce heart and metabolic health risks in people with high blood pressure

  This study is looking at how getting more sleep can help improve heart and metabolic health for adults with high blood pressure, and it involves using sleep trackers, helpful emails, and phone coaching over a year to support participants in extending their sleep.

  NIH research University of Utah · Salt Lake City, United States · NIH-10853108

• Improving health care for cardiometabolic diseases in low- and middle-income countries

  This study is all about helping people in Nepal and Kenya who are dealing with heart and metabolic health issues, like high blood pressure and insulin problems, by providing training and support to local healthcare workers so they can better care for their communities.

  NIH research University of Washington · Seattle, United States · NIH-10842399

Related topics

Quick answers

How many Cardiometabolic Risk Factors clinical trials are recruiting right now?

12, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in United States (3 trials), Canada (1 trial), Sweden (1 trial), Belgium (1 trial), India (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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