How pre-pregnancy health affects pregnancy complications and heart health later on

Intersections of pre-pregnancy cardiometabolic risk factors, preeclampsia and cardiovascular disease in a lifecourse framework

NIH-funded research Johns Hopkins University · NIH-11014058

This study is looking at how health issues like being overweight or having high blood pressure before pregnancy might lead to preeclampsia, a serious condition during pregnancy, and it aims to find out how these factors can affect heart health for women after they give birth, so we can improve care and prevention for those who experience it.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11014058 on NIH RePORTER

What this research studies

This research investigates the connections between pre-pregnancy cardiometabolic risk factors, such as obesity and hypertension, and the development of preeclampsia, a serious pregnancy complication. It aims to identify different types of preeclampsia using advanced machine learning techniques and to assess how these risk factors influence heart health in women after pregnancy. By analyzing clinical measures and biomarkers, the study seeks to understand long-term cardiovascular risks associated with preeclampsia. This research will provide valuable insights that could lead to better prevention and treatment strategies for affected women.

Who could benefit from this research

Good fit: Ideal candidates for this research are women who are pregnant or planning to become pregnant and have pre-existing cardiometabolic risk factors.

Not a fit: Patients who are not pregnant or do not have any cardiometabolic risk factors may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing preeclampsia and reducing long-term cardiovascular risks in women.

How similar studies have performed: Previous research has shown promising results in understanding the links between pregnancy complications and long-term health outcomes, suggesting that this approach could yield valuable insights.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Atherosclerotic Cardiovascular Diseaseatherosclerotic diseaseatherosclerotic vascular disease
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.