Understanding and treating obesity in young people with type 1 diabetes
Obesity complicating type 1 diabetes in young people: Physiology and Impact of GLP-1 analogue anti-obesity treatment on cardiometabolic risk factors
This research explores how a medication for obesity, called a GLP-1 analogue, helps young people with type 1 diabetes manage their weight and reduce heart-related health risks.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11126759 on NIH RePORTER |
What this research studies
We want to understand how obesity affects young people who also have type 1 diabetes, especially regarding their heart health. Our team will use special scans, like MRI and DEXA, to look at body fat distribution and overall body composition. We will also perform tests to see how the body handles sugar and fats. The goal is to see if a GLP-1 analogue medication can improve these health markers and reduce future risks for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are young people, including adolescents and young adults, who have type 1 diabetes and are also experiencing obesity or overweight.
Not a fit: Patients who do not have type 1 diabetes or who are not in the adolescent and young adult age range may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to better ways to manage obesity and reduce the risk of heart disease in young people living with type 1 diabetes.
How similar studies have performed: Preliminary data suggests that young people with type 1 diabetes often have high visceral fat, and GLP-1 analogues are already used for obesity treatment, indicating this builds on existing knowledge.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Van Name, Michelle — Yale University
- Study coordinator: Van Name, Michelle
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.