Analyzing corneal astigmatism measurements in different regions
Official title: Accuracy of Corneal Astigmatism in Different Region Modes
Run by Wenzhou Medical University · NCT03299530 · Data updated 2026-11-12
This study is testing how different ways of measuring corneal astigmatism can help improve accuracy for patients who have had cataract surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 70 (estimated) |
| Sponsor | Wenzhou Medical University Academic / other |
| Locations | 1 site (Wenzhou, Zhejiang) |
| Status | Recruiting |
| Started | October 10, 2017 |
| Main results expected | June 10, 2027 |
| Study ends | October 28, 2027 |
| Registry record updated | August 19, 2026 |
| Trial ID | NCT03299530 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older who have undergone cataract surgery and have a certain level of corneal astigmatism.
✕Probably not a fit
Patients with severe irregular astigmatism, corneal diseases, or other ocular conditions that may affect visual acuity are unlikely to benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to evaluate the differences between measured total corneal astigmatism and actual corneal astigmatism using various regional modes. The goal is to optimize the region settings for more accurate assessments. Patients with corneal astigmatism who have undergone phacoemulsification surgery will be included in the analysis. The study will focus on understanding how pupil size and other factors influence astigmatism measurements.
Why it matters
Potential benefit: If successful, this study could lead to improved accuracy in diagnosing and treating corneal astigmatism, enhancing visual outcomes for patients.
How similar studies have gone: While there may be studies on corneal astigmatism, this specific approach to analyzing measurements under different regional modes is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years * Patients who had received phacoemulsification surgery with or without implantation of toric IOL are with a certain amount of corneal astigmatism. * Best corrected visual acuity ≥ 0.66 (20/30 Snellen) Exclusion Criteria: * Corneal diseases or severe irregular astigmatism (e.g., pterygium, keratoconus), existence of corneal opacification; * Ocular disease which may affect visual acuity (e.g., glaucoma, uveitis, retinal disease, pathologic myopia); * History of ocular surgery or ocular trauma before this cataract surgery; * Decentration of IOL \> 0.3mm or tilt \> 5° * Implantation of multifocal IOL * history of wearing of rigid contact lens within the past 4 weeks or soft contact lens within 1 week;
Where it's running
-
Eye Hispital of Wenzhou Medical University
Wenzhou, Zhejiang, China Recruiting
Study contacts
- Principal investigator: AYong Yu, MD.PhD. — Wenzhou Medical University
- Study coordinator: AYong Yu, MD.PhD.
- Email: yaybetter@hotmail.com
- Phone: +86-0577-88068880
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Two monthly silicone hydrogel multifocal toric contact lenses in wearers with astigmatism and myopia
This study tests whether two popular soft multifocal toric contact lenses perform differently in adults who need vision correction for astigmatism and myopia.
-
Seeing clearly in low light after Ray-Tracing guided LASIK
A trial tests how well WaveLight Plus LASIK works for people with myopia and astigmatism and whether patients are satisfied after the procedure.
-
Orthokeratology contact lenses with a 5 mm optic zone diameter
This study tests Paragon CRT lenses with a 5 mm optic zone in kids and young adults to see how well they fit, how well they vision, and how comfortable they are at night.
-
Corneal Biomechanics and Surgical Astigmatism after Cataract Surgery in Pseudoexfoliation
This study tests how the cornea's biomechanical properties before cataract surgery relate to the amount of blinking surgically induced astigmatism, comparing people with pseudoexfoliation to those without.
-
SMILE in one eye vs Ray tracing-guided LASIK in the fellow eye
This study tests two laser vision correction methods—SMILE in one eye and ray-tracing guided LASIK in the other eye—to see which provides better vision and quality of life for adults with myopia and astigmatism.
-
GLP-1 receptor agonists and dry eye in adults with type 2 diabetes and obesity
This study tests whether GLP-1 receptor agonists affect dry eye disease in adults with type 2 diabetes and obesity.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.