Clinical trial Recruiting at 1 site Interventional Ages 18 to 45

Nomogram for Astigmatism Correction of KLEx

Official title: Nomogram Optimization for Astigmatism Precision Correction of Corneal Refractive Correction

Run by Tianjin Eye Hospital · NCT07605221 · Data updated 2026-11-12

This study tests whether using a nomogram can improve outcomes after astigmatism correction in adults who meet certain eye health criteria.

Quick facts

Study typeInterventional
Ages18 Years to 45 Years
SexAll
Enrollment100 (estimated)
SponsorTianjin Eye Hospital
Academic / other
Locations1 site (Tianjin, Tianjin Municipality)
StatusRecruiting
StartedFebruary 18, 2025
Main results expectedDecember 31, 2026
Study endsDecember 31, 2027
Registry record updatedMay 22, 2026
Trial IDNCT07605221 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18 and older with stable refractive error within the specified range, normal corneal topography, sufficient corneal thickness, and controlled intraocular pressure.

Probably not a fit

Individuals with ocular or systemic diseases or not meeting the corneal thickness or refractive criteria may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study investigates the use of a nomogram to guide astigmatism correction. Eligible participants are adults 18 years and older with specific refractive errors and healthy corneal measurements. Participants will be followed for 3 months with manifest refraction and visual acuity assessments to compare nomogram-guided treatment with non-nomogram approaches. The study aims to see if the nomogram can lead to acceptable, if not improved, treatment results. Additional details on methodology and outcomes are not provided in the available summary.

Why it matters

Potential benefit: If successful, participants could experience more accurate astigmatism correction and better postoperative vision.

How similar studies have gone: Previous studies have explored nomograms in refractive planning with mixed but potentially positive results; this trial explores a similar approach in KLEx without listed collaborators.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* age ≥18 years; preoperative sphere -0.50 D to -10.00 D; preoperative cylinder -1.50 D to -5.00 D; stable refraction (±0.50 D) for 1 year; normal corneal topography; central corneal thickness \>500 μm or predicted residual stromal bed \>280 μm; intraocular pressure \<21 mmHg

Exclusion Criteria:

* ocular or systematic disease

Where it's running

  • Tianjin Eye Hospital
    Tianjin, Tianjin Municipality, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.