Nomogram for Astigmatism Correction of KLEx
Official title: Nomogram Optimization for Astigmatism Precision Correction of Corneal Refractive Correction
Run by Tianjin Eye Hospital · NCT07605221 · Data updated 2026-11-12
This study tests whether using a nomogram can improve outcomes after astigmatism correction in adults who meet certain eye health criteria.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 45 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Tianjin Eye Hospital Academic / other |
| Locations | 1 site (Tianjin, Tianjin Municipality) |
| Status | Recruiting |
| Started | February 18, 2025 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2027 |
| Registry record updated | May 22, 2026 |
| Trial ID | NCT07605221 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 and older with stable refractive error within the specified range, normal corneal topography, sufficient corneal thickness, and controlled intraocular pressure.
✕Probably not a fit
Individuals with ocular or systemic diseases or not meeting the corneal thickness or refractive criteria may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study investigates the use of a nomogram to guide astigmatism correction. Eligible participants are adults 18 years and older with specific refractive errors and healthy corneal measurements. Participants will be followed for 3 months with manifest refraction and visual acuity assessments to compare nomogram-guided treatment with non-nomogram approaches. The study aims to see if the nomogram can lead to acceptable, if not improved, treatment results. Additional details on methodology and outcomes are not provided in the available summary.
Why it matters
Potential benefit: If successful, participants could experience more accurate astigmatism correction and better postoperative vision.
How similar studies have gone: Previous studies have explored nomograms in refractive planning with mixed but potentially positive results; this trial explores a similar approach in KLEx without listed collaborators.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * age ≥18 years; preoperative sphere -0.50 D to -10.00 D; preoperative cylinder -1.50 D to -5.00 D; stable refraction (±0.50 D) for 1 year; normal corneal topography; central corneal thickness \>500 μm or predicted residual stromal bed \>280 μm; intraocular pressure \<21 mmHg Exclusion Criteria: * ocular or systematic disease
Where it's running
-
Tianjin Eye Hospital
Tianjin, Tianjin Municipality, China Recruiting
Study contacts
- Study coordinator: Jiamei Zhang
- Email: jiamei3536@163.com
- Phone: 022-27305083
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.