Clareon TruPlus IOLs in Bilateral Cataract Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study implants Clareon TruPlus Monofocal intraocular lenses (IOLs) during cataract surgery to gather safety and performance data. Participants may receive either non-toric or toric IOLs based on an IOL calculator recommendation. The study involves eight visits over about 13 months, including preoperative, two surgical, and five postoperative visits, with the second-eye surgery typically 0–14 days after the first. Key eligibility targets adults with bilateral cataracts and acceptable best-corrected vision, while excluding eyes with certain retinal or ocular conditions that could affect measurements. Phacoemulsification is the surgical method used, and all procedures are conducted at multiple clinical sites under the lead sponsor Alcon Research.

Why it matters

Who can join: the full rules

Key Inclusion Criteria:

* Diagnosed with bilateral cataracts and planned bilateral cataract extraction by routine phacoemulsification.
* Potential postoperative BCDVA of 0.2 logMAR or better in each eye in the expert medical opinion of the investigator.
* Astigmatism suitable for correction with available toric IOL models.
* Other protocol-specified inclusion criteria may apply.

Key Exclusion Criteria:

* Age-related macular degeneration (AMD), glaucoma, diabetic retinopathy, and other eye conditions as specified in the protocol.
* Moderate to severe dry eye that would affect study measurements.
* Other protocol-specified exclusion criteria may apply.

Where it's running

• Eye Doctors of Arizona
  Phoenix, Arizona, United States Recruiting
• Cleveland Eye Clinic
  Brecksville, Ohio, United States Recruiting
• Carolina Eyecare Physicians LLC
  Mt. Pleasant, South Carolina, United States Recruiting
• Berkeley Eye Center
  Sugar Land, Texas, United States Recruiting
• The Eye Institute of Utah
  Salt Lake City, Utah, United States Recruiting

Study contacts

• Study coordinator: Alcon Call Center
• Email: alcon.medinfo@alcon.com
• Phone: 1-888-451-3937

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Two monthly silicone hydrogel multifocal toric contact lenses in wearers with astigmatism and myopia

  This study tests whether two popular soft multifocal toric contact lenses perform differently in adults who need vision correction for astigmatism and myopia.

  Recruiting CooperVision International Limited (CVIL) · New York, New York and 2 other locations · NCT07829419

• Seeing clearly in low light after Ray-Tracing guided LASIK

  A trial tests how well WaveLight Plus LASIK works for people with myopia and astigmatism and whether patients are satisfied after the procedure.

  Recruiting Phase 4 Vance Thompson Vision · Sioux Falls, South Dakota · NCT07790185

• Orthokeratology contact lenses with a 5 mm optic zone diameter

  This study tests Paragon CRT lenses with a 5 mm optic zone in kids and young adults to see how well they fit, how well they vision, and how comfortable they are at night.

  Recruiting at 2 sites CooperVision International Limited (CVIL) · Pleasanton, California and 2 other locations · NCT07751172

• Corneal Biomechanics and Surgical Astigmatism after Cataract Surgery in Pseudoexfoliation

  This study tests how the cornea's biomechanical properties before cataract surgery relate to the amount of blinking surgically induced astigmatism, comparing people with pseudoexfoliation to those without.

  Recruiting Eye Clinic Medic Zuljan Jukic · Split, Splitsko-dalmatinska County · NCT07722247

• SMILE in one eye vs Ray tracing-guided LASIK in the fellow eye

  This study tests two laser vision correction methods—SMILE in one eye and ray-tracing guided LASIK in the other eye—to see which provides better vision and quality of life for adults with myopia and astigmatism.

  Recruiting Phase 4 Stanford University · Palo Alto, California · NCT07721714

• Nomogram for Astigmatism Correction of KLEx

  This study tests whether using a nomogram can improve outcomes after astigmatism correction in adults who meet certain eye health criteria.

  Recruiting Tianjin Eye Hospital · Tianjin, Tianjin Municipality · NCT07605221

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.