Daily disposable toric contact lenses for long-day wear.
Official title: Wear Experience With Daily Disposable Contact Lenses for Astigmatism Over a Long-Wear Day
Run by Ohio State University · NCT07303920 · Data updated 2026-11-12
This will test whether daily disposable toric contact lenses stay comfortable and provide clear vision for people with astigmatism who wear lenses for long days.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 40 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Ohio State University Academic / other |
| Locations | 1 site (Columbus, Ohio) |
| Status | Recruiting |
| Started | March 4, 2026 |
| Main results expected | December 30, 2026 |
| Study ends | December 30, 2026 |
| Registry record updated | September 25, 2026 |
| Trial ID | NCT07303920 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults with astigmatism who currently wear soft toric lenses for long hours, have 20/25 vision or better with those lenses, and can attend the Columbus, Ohio site.
✕Probably not a fit
Patients with dry eye, active ocular inflammation or infection, prior corneal/ocular surgery, corneal dystrophies, systemic conditions that alter tear film, past rigid lens wear, or who are pregnant or breastfeeding are unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study enrolls current soft toric contact lens wearers who routinely have long hours of wear. Participants will wear a daily disposable toric lens through extended waking hours and report on comfort and vision throughout the day. Eligible participants must have 20/25 vision or better with their current toric lenses and a comprehensive eye exam within the past two years, while those with ocular surface disease, prior corneal surgery, or systemic conditions affecting tear film are excluded. The trial is conducted at The Ohio State University College of Optometry in Columbus, Ohio in collaboration with a contact lens manufacturer.
Why it matters
Potential benefit: If successful, this could provide people with astigmatism a comfortable single-use lens option that maintains clear vision during long wearing days.
How similar studies have gone: Previous research on daily disposable toric lenses has generally shown good comfort and stable vision, though results can vary by individual fit and lens design.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Current soft toric contact lens wearer with long hours of wear * Willing to follow the contact lens wearing schedule required by the study * Vision 20/25 or better with current soft toric contact lenses * Self-report completion of a comprehensive eye examination in the past two years Exclusion Criteria: * Have a history of corneal ocular surgery * Have current ocular inflammation or infection as assessed by the study investigator who will complete the study * Are past rigid contact lens wearers * Have a history of being diagnosed with dry eye or ocular allergies * Have known systemic health conditions that are thought to alter tear film physiology * Have a history of viral eye disease * Have a history of ocular surgery * Have a history of severe ocular trauma * Have a history of corneal dystrophies or degenerations * Have active ocular infection or inflammation * Are currently using isotretinoin-derivatives or ocular medications * Are pregnant or breast feeding
Where it's running
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The Ohio State University College of Optometry
Columbus, Ohio, United States Recruiting
Study contacts
- Study coordinator: Study Coordinators
- Email: OPT-EyeStudies@osu.edu
- Phone: 614-292-8858
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.