Clinical trial Recruiting at 1 site Observational Ages 18 and up

Risk of malignant arrhythmias after acute coronary syndrome

Official title: Current Relevance of Malignant Cardiac Arrhythmia in Patients Admitted for Acute Coronary Syndrome

Run by Catharina Ziekenhuis Eindhoven · NCT07824050 · Data updated 2026-11-12

This study tracks how often dangerous heart rhythms occur in adults admitted for ACS and looks for patterns that might predict them.

More Cardiac Arrest (CA) trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment2775 (estimated)
SponsorCatharina Ziekenhuis Eindhoven
Academic / other
Locations1 site (Eindhoven, North Brabant)
StatusRecruiting
StartedJuly 14, 2026
Main results expectedApril 1, 2029
Study endsApril 1, 2029
Registry record updatedOctober 13, 2026
Trial IDNCT07824050 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18 years or older admitted with ACS (STEMI, NSTEMI, unstable angina) or out-of-hospital cardiac arrest due to ACS, admitted to relevant hospital units.

Probably not a fit

Patients without malignant arrhythmias or those not at risk for such events may not benefit from this observational analysis.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study analyzes the incidence of malignant arrhythmias, specifically sustained VT and VF, in adults admitted with acute coronary syndromes. It aims to identify timing and predictors of these events during initial hospitalization across STEMI, NSTEMI, and unstable angina. Secondary questions examine the distribution of arrhythmias, differences between polymorphic and monomorphic VT, associated in-hospital mortality, and the occurrence of asystole/PEA. The research uses existing hospital data from ICSU units to characterize risk and inform monitoring practices. Interventions are not being tested; the study observes real-world care as it occurs.

Why it matters

Potential benefit: Findings could improve risk stratification and monitoring decisions for ACS patients, potentially reducing arrhythmia-related complications and deaths.

How similar studies have gone: Previous observational work in ACS has shown that certain factors predict arrhythmic risk, supporting the value of this approach but the exact risk patterns may vary by center.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion criteria Patients

* Aged 18 years or older
* With acute coronary syndrome (ST-elevation myocardial infarction, non-ST-elevation myocardial infarction, and unstable angina pectoris) or out-of-hospital cardiac arrest (OHCA) due to ACS
* Admitted to the emergency cardiac care unit, emergency department, coronary care unit (CCU), intensive care unit (ICU), or cardiology ward.

Exclusion criteria

\- Patients who have indicated that their data may not be used for scientific research or for improving the quality of care.

Where it's running

  • Catharina Hospital Eindhoven
    Eindhoven, North Brabant, Netherlands
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.